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34287102 | Marked and prolonged serotonin toxicity in a tramadol-poisoned patient with a pharmacokinetic study. | 2022 Mar |
3 |
| 2 |
35586822 | Plasma Drug Concentration of Propranolol and Genetic Study in Chinese Han Patients With Infantile Haemangioma. | 2022 |
1 |
| 3 |
34581987 | Sex and Estrous Cycle Differences in Analgesia and Brain Oxycodone Levels. | 2021 Dec |
2 |
| 4 |
30604050 | Phenoconversion of CYP2D6 by inhibitors modifies aripiprazole exposure. | 2020 Feb |
1 |
| 5 |
31648367 | Propranolol is a mechanism-based inhibitor of CYP2D and CYP2D6 in humanized CYP2D6-transgenic mice: Effects on activity and drug responses. | 2020 Feb |
5 |
| 6 |
32189192 | Human CYP2D6 Is Functional in Brain In Vivo: Evidence from Humanized CYP2D6 Transgenic Mice. | 2020 Jun |
1 |
| 7 |
32219146 | Influence of Cytochrome P450 2D6 Polymorphisms on the Efficacy of Oral Propranolol in Treating Infantile Hemangioma. | 2020 |
5 |
| 8 |
32286940 | Clinical Pharmacokinetics of Propranolol Hydrochloride: A Review. | 2020 |
1 |
| 9 |
32761352 | Human CYP2D6 in the Brain Is Protective Against Harmine-Induced Neurotoxicity: Evidence from Humanized CYP2D6 Transgenic Mice. | 2020 Nov |
1 |
| 10 |
26489037 | Influence of CYP2D6 and β2-adrenergic receptor gene polymorphisms on the hemodynamic response to propranolol in Chinese Han patients with cirrhosis. | 2016 Apr |
4 |
| 11 |
24119207 | Possibility of decrease in CYP1A2 function in patients with end-stage renal disease. | 2014 Apr |
1 |
| 12 |
23287855 | Heterologous expression of CYP102A5 variant from Bacillus cereus CYPPB-1: Validation of model for predicting drug metabolism of human P450 probe substrates. | 2013 Sep |
1 |
| 13 |
22764579 | Comparison of catalytical activity and stereoselectivity between the recombinant human cytochrome P450 2D6.1 and 2D6.10. | 2012 May |
4 |
| 14 |
21110747 | Microbial production of phase I and phase II metabolites of propranolol. | 2011 Mar |
1 |
| 15 |
21184751 | Regio- and stereoselective oxidation of propranolol enantiomers by human CYP2D6, cynomolgus monkey CYP2D17 and marmoset CYP2D19. | 2011 Feb 1 |
5 |
| 16 |
20345925 | Cytochrome P450 2D6 enzyme neuroprotects against 1-methyl-4-phenylpyridinium toxicity in SH-SY5Y neuronal cells. | 2010 Apr |
1 |
| 17 |
20372009 | Estimating pediatric doses of drugs metabolized by cytochrome P450 (CYP) isozymes, based on physiological liver development and serum protein levels. | 2010 Apr |
1 |
| 18 |
19817501 | Polymorphism of human cytochrome P450 2D6 and its clinical significance: Part I. | 2009 |
1 |
| 19 |
18535530 | [Drug-induced pneumonitis in a patient treated with venlafaxine and propanolol]. | 2008 May |
1 |
| 20 |
17333164 | Free energies of binding of R- and S-propranolol to wild-type and F483A mutant cytochrome P450 2D6 from molecular dynamics simulations. | 2007 Jul |
3 |
| 21 |
12728976 | Dose-response relationships of propranolol in Chinese subjects with different CYP2D6 genotypes. | 2003 Jan |
7 |
| 22 |
11602512 | Importance of amine pKa and distribution coefficient in the metabolism of fluorinated propranolol derivatives. Preparation, identification of metabolite regioisomers, and metabolism by CYP2D6. | 2001 Nov |
1 |
| 23 |
10903420 | Species difference in enantioselectivity for the oxidation of propranolol by cytochrome P450 2D enzymes. | 2000 Jun 15 |
2 |
| 24 |
10945865 | CYP1A2 and CYP2D6 4-hydroxylate propranolol and both reactions exhibit racial differences. | 2000 Sep |
3 |
| 25 |
11038161 | Automated definition of the enzymology of drug oxidation by the major human drug metabolizing cytochrome P450s. | 2000 Nov |
1 |
| 26 |
9256169 | Specific binding of 1-[2-(diphenylmethoxy)ethyl]-4-(3-phenyl propyl) piperazine (GBR-12935), an inhibitor of the dopamine transporter, to human CYP2D6. | 1997 Jun 15 |
2 |
| 27 |
9399616 | Impact of CYP2D6 poor metabolizer phenotype on propranolol pharmacokinetics and response. | 1997 Nov-Dec |
3 |
| 28 |
8877032 | Variable contribution of CYP2D6 to the N-dealkylation of S-(-)-propranolol by human liver microsomes. | 1996 Sep |
3 |
| 29 |
8946477 | CYP2D6 is the principal cytochrome P450 responsible for metabolism of the histamine H1 antagonist promethazine in human liver microsomes. | 1996 Oct |
1 |
| 30 |
7554699 | Propranolol disposition in Chinese subjects of different CYP2D6 genotypes. | 1995 Sep |
3 |
| 31 |
7640150 | Identification of human CYP isoforms involved in the metabolism of propranolol enantiomers--N-desisopropylation is mediated mainly by CYP1A2. | 1995 Apr |
5 |
| 32 |
7895609 | Cytochrome P450 isozymes involved in propranolol metabolism in human liver microsomes. The role of CYP2D6 as ring-hydroxylase and CYP1A2 as N-desisopropylase. | 1994 Nov-Dec |
2 |
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7946944 | Inhibition of CYP2D6 activity by treatment with propranolol and the role of 4-hydroxy propranolol. | 1994 Jul |
4 |