20 Article(s)Download |
PMID | Title | Pub. Year | #Total Relationships |
1 | 27632988 | Computational Analysis of Physicochemical Factors Driving CYP2D6 Ligand Interaction. | 2017 | 1 |
2 | 27440861 | The Use of In Vitro Data and Physiologically-Based Pharmacokinetic Modeling to Predict Drug Metabolite Exposure: Desipramine Exposure in Cytochrome P4502D6 Extensive and Poor Metabolizers Following Administration of Imipramine. | 2016 Oct | 3 |
3 | 25719307 | Pharmacogenetics of drug oxidation via cytochrome P450 (CYP) in the populations of Denmark, Faroe Islands and Greenland. | 2015 Sep | 1 |
4 | 22764579 | Comparison of catalytical activity and stereoselectivity between the recombinant human cytochrome P450 2D6.1 and 2D6.10. | 2012 May | 2 |
5 | 28520379 | Imipramine Therapy and CYP2D6 and CYP2C19 Genotype | 2012 | 1 |
6 | 19884907 | The CYP2C19*17 genotype is associated with lower imipramine plasma concentrations in a large group of depressed patients. | 2010 Jun | 1 |
7 | 17667959 | Association of graded allele-specific changes in CYP2D6 function with imipramine dose requirement in a large group of depressed patients. | 2008 Jun | 9 |
8 | 18310890 | Effect of psychotropic drugs on the 21-hydroxylation of neurosteroids, progesterone and allopregnanolone, catalyzed by rat CYP2D4 and human CYP2D6 in the brain. | 2008 Mar | 3 |
9 | 15687478 | QTc prolongation associated with combination therapy of levofloxacin, imipramine, and fluoxetine. | 2005 Mar | 1 |
10 | 16141545 | Contribution of human hepatic cytochrome p450 isoforms to the metabolism of psychotropic drugs. | 2005 Sep | 2 |
11 | 12695349 | Impact of nonspecific binding to microsomes and phospholipid on the inhibition of cytochrome P4502D6: implications for relating in vitro inhibition data to in vivo drug interactions. | 2003 May | 1 |
12 | 12065442 | Measurement of Michaelis constants for cytochrome P450-mediated biotransformation reactions using a substrate depletion approach. | 2002 Jul | 1 |
13 | 9205822 | Venlafaxine: in vitro inhibition of CYP2D6 dependent imipramine and desipramine metabolism; comparative studies with selected SSRIs, and effects on human hepatic CYP3A4, CYP2C9 and CYP1A2. | 1997 Jun | 4 |
14 | 9256169 | Specific binding of 1-[2-(diphenylmethoxy)ethyl]-4-(3-phenyl propyl) piperazine (GBR-12935), an inhibitor of the dopamine transporter, to human CYP2D6. | 1997 Jun 15 | 2 |
15 | 9505989 | Olanzapine: interaction study with imipramine. | 1997 Oct | 1 |
16 | 9512923 | Synthetic strategies to lower affinity for CYP2D6. | 1997 Oct-Dec | 3 |
17 | 8835703 | Steady-state plasma concentrations of imipramine and desipramine in relation to S-mephenytoin 4'-hydroxylation status in Japanese depressive patients. | 1996 Aug | 1 |
18 | 8521680 | Geographical/interracial differences in polymorphic drug oxidation. Current state of knowledge of cytochromes P450 (CYP) 2D6 and 2C19. | 1995 Sep | 1 |
19 | 8310712 | Analysis of imipramine and three metabolites produced by isozyme CYP2D6 expressed in a human cell line. | 1993 Nov | 3 |
20 | 8335704 | Metabolism of imipramine in vitro by isozyme CYP2D6 expressed in a human cell line, and observations on metabolite stability. | 1993 Jun 2 | 3 |