Paliperidone Palmitate

cytochrome P450 family 2 subfamily D member 6 ; Homo sapiens







46 Article(s)
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1 32682874 ABCB1, ABCG2 and CYP2D6 polymorphism effects on disposition and response to long-acting risperidone. 2021 Jan 10 1
2 33400943 Effects of CYP2D6, CYP3A5, and ABCB1 gene polymorphisms on the pharmacokinetics of two risperidone long-acting injection microsphere formulations. 2021 Jul 13 1
3 31359271 Physiologically Based Pharmacokinetic Modelling to Describe the Pharmacokinetics of Risperidone and 9-Hydroxyrisperidone According to Cytochrome P450 2D6 Phenotypes. 2020 Jan 2
4 32476097 Modelling Age-Related Changes in the Pharmacokinetics of Risperidone and 9-Hydroxyrisperidone in Different CYP2D6 Phenotypes Using a Physiologically Based Pharmacokinetic Approach. 2020 May 31 2
5 32519344 CYP2D6 Genetic Polymorphisms and Risperidone Pharmacokinetics: A Systematic Review and Meta-analysis. 2020 Jul 3
6 31000417 Effect of CYP2D6 genotype on exposure and efficacy of risperidone and aripiprazole: a retrospective, cohort study. 2019 May 1
7 30093744 A Prospective Study to Evaluate the Effect of CYP2D6 Polymorphism on Plasma level of Risperidone and its Metabolite in North Indian Patients with Schizophrenia. 2018 Jul-Aug 1
8 26780783 Impact of CYP2D6 Polymorphism on Steady-State Plasma Levels of Risperidone and 9-Hydroxyrisperidone in Thai Children and Adolescents with Autism Spectrum Disorder. 2017 Mar 3
9 27738718 Erratum to: Genotype and co-medication dependent CYP2D6 metabolic activity: effects on serum concentrations of aripiprazole, haloperidol, risperidone, paliperidone and zuclopenthixol. 2017 Jan 1
10 28133766 Exposure-response analysis after subcutaneous administration of RBP-7000, a once-a-month long-acting Atrigel formulation of risperidone. 2017 Jul 1
11 26418700 Risperidone and Venlafaxine Metabolic Ratios Strongly Predict a CYP2D6 Poor Metabolizing Genotype. 2016 Feb 1
12 26514968 Genotype and co-medication dependent CYP2D6 metabolic activity: effects on serum concentrations of aripiprazole, haloperidol, risperidone, paliperidone and zuclopenthixol. 2016 Feb 2
13 26944100 Detection of CYP2D6 polymorphism using Luminex xTAG technology in autism spectrum disorder: CYP2D6 activity score and its association with risperidone levels. 2016 Apr 2
14 27145399 Impact of Ageing on Serum Concentrations of Risperidone and Its Active Metabolite in Patients with Known CYP2D6 Genotype. 2016 Nov 1
15 27942231 CYP2D6 polymorphisms and their influence on risperidone treatment. 2016 1
16 26129906 Genetics-Based Population Pharmacokinetics and Pharmacodynamics of Risperidone in a Psychiatric Cohort. 2015 Dec 1
17 26387027 Evaluation of potential pharmacokinetic drug-drug interaction between armodafinil and risperidone in healthy adults. 2015 Nov 1
18 22623266 Population pharmacokinetic analysis of risperidone and 9-hydroxyrisperidone with genetic polymorphisms of CYP2D6 and ABCB1. 2012 Aug 6
19 22929407 Population pharmacokinetic modeling of risperidone and 9-hydroxyrisperidone to estimate CYP2D6 subpopulations in children and adolescents. 2012 Oct 2
20 28520384 Risperidone Therapy and CYP2D6 Genotype 2012 1
21 21387786 [The review of acute risperidone poisoning]. 2010 2
22 19387994 Effects of the CYP2D6*10 alleles and co-medication with CYP2D6-dependent drugs on risperidone metabolism in patients with schizophrenia. 2009 Jun 1
23 19440082 Effects of CYP2D6 and CYP3A5 genotypes on the plasma concentrations of risperidone and 9-hydroxyrisperidone in Korean schizophrenic patients. 2009 Jun 1
24 19910717 Impact of CYP2D6 genotype on steady-state serum concentrations of risperidone and 9-hydroxyrisperidone in patients using long-acting injectable risperidone. 2009 Dec 2
25 18708991 ABCB1 polymorphisms influence steady-state plasma levels of 9-hydroxyrisperidone and risperidone active moiety. 2008 Oct 2
26 18728628 Impact of multiple inhibitors or substrates of cytochrome P450 2D6 on plasma risperidone levels in patients on polypharmacy. 2008 Oct 3
27 17541883 A study of genetic (CYP2D6 and ABCB1) and environmental (drug inhibitors and inducers) variables that may influence plasma risperidone levels. 2007 May 1
28 17715206 Serum prolactin levels, plasma risperidone levels, polymorphism of cytochrome P450 2D6 and clinical response in patients with schizophrenia. 2007 Nov 1
29 16833023 Pharmacokinetics and bioequivalence evaluation of risperidone in healthy male subjects with different CYP2D6 genotypes. 2006 Jun 2
30 15565299 Risperidone plasma levels, clinical response and side-effects. 2005 Aug 2
31 16321618 Cytochrome P450 3A inhibitor itraconazole affects plasma concentrations of risperidone and 9-hydroxyrisperidone in schizophrenic patients. 2005 Nov 2
32 15089809 Effects of various factors on steady-state plasma concentrations of risperidone and 9-hydroxyrisperidone: lack of impact of MDR-1 genotypes. 2004 May 1
33 15260906 QTc interval, CYP2D6 and CYP2C9 genotypes and risperidone plasma concentrations. 2004 Jun 2
34 15270204 The role of cytochrome P450 enzymes in the metabolism of risperidone and its clinical relevance for drug interactions. 2004 Aug 5
35 12616663 Effects of CYP2D6 genotypes on plasma concentrations of risperidone and enantiomers of 9-hydroxyrisperidone in Japanese patients with schizophrenia. 2003 Feb 4
36 12107617 Significant pharmacokinetic interaction between risperidone and carbamazepine: its relationship with CYP2D6 genotypes. 2002 Jun 1
37 12518271 Relationship between risperidone and 9-hydroxy-risperidone plasma concentrations and CYP2D6 enzyme activity in psychiatric patients. 2002 Nov 1
38 11360029 Plasma concentrations of risperidone and 9-hydroxyrisperidone during combined treatment with paroxetine. 2001 Jun 1
39 11560868 Different enantioselective 9-hydroxylation of risperidone by the two human CYP2D6 and CYP3A4 enzymes. 2001 Oct 4
40 11791898 Risperidone metabolism in relation to CYP2D6*10 allele in Korean schizophrenic patients. 2001 Nov 2
41 10771452 Identification of the major human liver cytochrome P450 isoform(s) responsible for the formation of the primary metabolites of ziprasidone and prediction of possible drug interactions. 2000 2
42 10048600 Metabolism of risperidone to 9-hydroxyrisperidone by human cytochromes P450 2D6 and 3A4. 1999 Feb 2
43 10453802 A pilot study on risperidone metabolism: the role of cytochromes P450 2D6 and 3A. 1999 Jul 2
44 10639689 Cytochrome P450 2D6 genotype and steady state plasma levels of risperidone and 9-hydroxyrisperidone. 1999 Dec 8
45 7545821 A PET study of D2 and 5-HT2 receptor occupancy induced by risperidone in poor metabolizers of debrisoquin and risperidone. 1995 Jun 1
46 7690693 Pharmacokinetics of the novel antipsychotic agent risperidone and the prolactin response in healthy subjects. 1993 Sep 1