Ticlopidine

cytochrome P450 family 2 subfamily D member 6 ; Homo sapiens







6 Article(s)
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1 23099620 Ticlopidine inhibits both O-demethylation and renal clearance of tramadol, increasing the exposure to it, but itraconazole has no marked effect on the ticlopidine-tramadol interaction. 2013 Apr 1
2 18474675 Cytochrome P450 2B6 catalyzes the formation of pharmacologically active sibutramine (N-{1-[1-(4-chlorophenyl)cyclobutyl]-3-methylbutyl}-N,N-dimethylamine) metabolites in human liver microsomes. 2008 Aug 1
3 19122335 Comparison of human cytochrome P450 inhibition by the thienopyridines prasugrel, clopidogrel, and ticlopidine. 2008 1
4 15155554 Selective inhibition of CYP2B6-catalyzed bupropion hydroxylation in human liver microsomes in vitro. 2004 Jun 1
5 10759690 In vitro inhibition of the cytochrome P450 (CYP450) system by the antiplatelet drug ticlopidine: potent effect on CYP2C19 and CYP2D6. 2000 Apr 3
6 10460802 The role of CYP2C19 in the metabolism of (+/-) bufuralol, the prototypic substrate of CYP2D6. 1999 Sep 1