Haloperidol

cytochrome P450 family 2 subfamily D member 6 ; Homo sapiens







53 Article(s)
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1 33118660 Impact of CYP2D6 on serum concentrations of flupentixol, haloperidol, perphenazine and zuclopenthixol. 2021 May 2
2 31648367 Propranolol is a mechanism-based inhibitor of CYP2D and CYP2D6 in humanized CYP2D6-transgenic mice: Effects on activity and drug responses. 2020 Feb 1
3 32208328 Pharmacogenomic response of low dose haloperidol in critically ill adults with delirium. 2020 Jun 2
4 29343979 The influence of CYP3A5 polymorphisms on haloperidol treatment in patients with alcohol addiction. 2018 1
5 29737183 Clozapine toxicity in a CYP2D6 poor metaboliser: Additive effects of haloperidol and valproate on clozapine metabolism. 2018 Dec 1
6 27738718 Erratum to: Genotype and co-medication dependent CYP2D6 metabolic activity: effects on serum concentrations of aripiprazole, haloperidol, risperidone, paliperidone and zuclopenthixol. 2017 Jan 1
7 28787271 Genotyping and phenotyping of CYP2D6 and CYP3A isoenzymes in patients with alcohol use disorder: correlation with haloperidol plasma concentration. 2017 Sep 26 4
8 26514968 Genotype and co-medication dependent CYP2D6 metabolic activity: effects on serum concentrations of aripiprazole, haloperidol, risperidone, paliperidone and zuclopenthixol. 2016 Feb 2
9 27469576 CYP2D6 *6/*6 genotype and drug interactions as cause of haloperidol-induced extrapyramidal symptoms. 2016 Aug 4
10 27695358 The correlation between CYP2D6 isoenzyme activity and haloperidol efficacy and safety profile in patients with alcohol addiction during the exacerbation of the addiction. 2016 4
11 25868121 The Influence of the CYP3A4*22 Polymorphism and CYP2D6 Polymorphisms on Serum Concentrations of Aripiprazole, Haloperidol, Pimozide, and Risperidone in Psychiatric Patients. 2015 Jun 1
12 26639694 CYP3A4 activity and haloperidol effects in alcohol addicts. 2015 4
13 24739668 Lack of correlation between the steady-state plasma concentrations of aripiprazole and haloperidol in Japanese patients with schizophrenia. 2014 Dec 1
14 24088126 Relationship between CYP2D6 genotype and haloperidol pharmacokinetics and extrapyramidal symptoms in healthy volunteers. 2013 Oct 3
15 20491279 [Clinical pharmacogenetics in the treatment of schizophrenia]. 2010 Apr 1
16 19817501 Polymorphism of human cytochrome P450 2D6 and its clinical significance: Part I. 2009 1
17 19902987 Polymorphism of human cytochrome P450 2D6 and its clinical significance: part II. 2009 2
18 17667795 Depot haloperidol treatment in outpatients with schizophrenia on monotherapy: impact of CYP2D6 polymorphism on pharmacokinetics and treatment outcome. 2007 Aug 3
19 16633141 Combined effects of itraconazole and CYP2D6*10 genetic polymorphism on the pharmacokinetics and pharmacodynamics of haloperidol in healthy subjects. 2006 Apr 6
20 16805946 Role of CYP pharmacogenetics and drug-drug interactions in the efficacy and safety of atypical and other antipsychotic agents. 2006 Jul 1
21 16910628 [Use of antidepressant drugs in schizophrenic patients with depression]. 2006 Mar-Apr 1
22 15572279 Inhibition of rat liver CYP2D in vitro and after 1-day and long-term exposure to neuroleptics in vivo-possible involvement of different mechanisms. 2005 Jan 1
23 16045195 [Clinical pharmacogenetics in the treatment of schizophrenia]. 2005 Jun 1
24 15048614 Relationship between haloperidol plasma concentration, debrisoquine metabolic ratio, CYP2D6 and CYP2C9 genotypes in psychiatric patients. 2004 Mar 6
25 12657913 Histamine H1-receptor antagonists, promethazine and homochlorcyclizine, increase the steady-state plasma concentrations of haloperidol and reduced haloperidol. 2003 Apr 3
26 12691769 Effects of age and the CYP2D6*10 allele on the plasma haloperidol concentration/dose ratio. 2003 May 4
27 12746736 Pharmacokinetics and QT interval pharmacodynamics of oral haloperidol in poor and extensive metabolizers of CYP2D6. 2003 1
28 12784098 Effect of CYP2D6 genotypes on the metabolism of haloperidol in a Japanese psychiatric population. 2003 Aug 18
29 12919180 Haloperidol plasma concentration in Japanese psychiatric subjects with gene duplication of CYP2D6. 2003 Sep 3
30 12960748 Cytochrome P450 II D6 gene polymorphisms and the neuroleptic-induced extrapyramidal symptoms in Japanese schizophrenic patients. 2003 Sep 2
31 14499311 Effects of smoking and cytochrome P450 2D6*10 allele on the plasma haloperidol concentration/dose ratio. 2003 Sep 3
32 12083975 Cytochrome p450 phenotyping/genotyping in patients receiving antipsychotics: useful aid to prescribing? 2002 2
33 12107857 Cytochrome P450 2D6 deficiency and its clinical relevance in a patient treated with risperidone. 2002 May 1
34 12362921 Lack of correlation between the steady-state plasma concentrations of haloperidol and risperidone. 2002 Oct 1
35 12386646 The impact of the CYP2D6 polymorphism on haloperidol pharmacokinetics and on the outcome of haloperidol treatment. 2002 Oct 5
36 11167668 Potent inhibition of CYP2D6 by haloperidol metabolites: stereoselective inhibition by reduced haloperidol. 2001 Jan 6
37 11477317 Importance of the cytochrome P450 2D6 genotype for the drug metabolic interaction between chlorpromazine and haloperidol. 2001 Aug 4
38 11560558 Plasma concentrations of haloperidol are related to CYP2D6 genotype at low, but not high doses of haloperidol in Korean schizophrenic patients. 2001 Sep 7
39 10688273 Pharmacogenetics of classical and new antipsychotic drugs. 2000 Feb 1
40 10850389 Effect of a genetic polymorphism of CYP1A2 inducibility on the steady state plasma concentrations of haloperidol and reduced haloperidol in Japanese patients with schizophrenia. 2000 Jun 1
41 10942177 CYP2D6*10 alleles are not the determinant of the plasma haloperidol concentrations in Asian patients. 2000 Aug 2
42 10096261 Effects of the CYP2D6*10 allele on the steady-state plasma concentrations of haloperidol and reduced haloperidol in Japanese patients with schizophrenia. 1999 Mar 2
43 10519444 Effects of smoking, CYP2D6 genotype, and concomitant drug intake on the steady state plasma concentrations of haloperidol and reduced haloperidol in schizophrenic inpatients. 1999 Oct 1
44 10541779 In vitro study on the involvement of CYP1A2, CYP2D6 and CYP3A4 in the metabolism of haloperidol and reduced haloperidol. 1999 Oct 6
45 10551545 Genetic association between cytochrome P-450 2D6 gene polymorphism and plasma concentration of haloperidol in Japanese schizophrenics. 1999 Sep 4
46 10595685 The effect of cytochrome P450 2D6 genotypes on haloperidol metabolism: a preliminary study in a psychiatric population. 1999 Oct 2
47 10628896 Pharmacokinetics of haloperidol: an update. 1999 Dec 3
48 9681669 Involvement of human cytochrome P450 3A4 in reduced haloperidol oxidation. 1998 May 7
49 9029745 Increases in plasma concentration of m-chlorophenylpiperazine, but not trazodone, with low-dose haloperidol. 1997 Feb 1
50 9140699 Involvement of CYP3A4 and CYP2D6 in the metabolism of haloperidol. 1997 Apr 2