Fluvoxamine

cytochrome P450 family 2 subfamily D member 6 ; Homo sapiens







53 Article(s)
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1 33897064 Impact of the Omics-Based Biomarkers on the Fluvoxamine's Steady-State Concentration, Efficacy and Safety in Patients with Affective Disorders Comorbid with Alcohol Use Disorder. 2021 Jan 12 1
2 34117140 Effect of Genetic Polymorphism of the CYP2D6 Gene on the Efficacy and Safety of Fluvoxamine in Major Depressive Disorder. 2021 Jun 3 8
3 34605737 Role of amino acids at positions 34, 296, and 486 of cytochrome P450 2D6 in the stimulatory and inhibitory effects of psychotropic agents on dopamine formation from p-tyramine. 2021 Nov 1
4 29988737 Effects of CYP2D6 genetic polymorphisms on the efficacy and safety of fluvoxamine in patients with depressive disorder and comorbid alcohol use disorder. 2018 5
5 28361099 A de novo splice site mutation in EHMT1 resulting in Kleefstra syndrome with pharmacogenomics screening and behavior therapy for regressive behaviors. 2017 Mar 1
6 21739267 The relationship between clinical pharmacokinetics of aripiprazole and CYP2D6 genetic polymorphism: effects of CYP enzyme inhibition by coadministration of paroxetine or fluvoxamine. 2012 Jan 6
7 20547595 CYP2D6 genotype and smoking influence fluvoxamine steady-state concentration in Japanese psychiatric patients: lessons for genotype-phenotype association study design in translational pharmacogenetics. 2011 Jul 6
8 21277363 Involvement of CYP3A4/5 and CYP2D6 in the metabolism of aconitine using human liver microsomes and recombinant CYP450 enzymes. 2011 Apr 10 1
9 20118554 Effects of cigarette smoking and cytochrome P450 2D6 genotype on fluvoxamine concentration in plasma of Japanese patients. 2010 2
10 18609433 A case with occurring adverse effects when cross-over titration from fluvoxamine to paroxetine associated with increasing the plasma fluvoxamine level in major depressive disorder. 2009 1
11 19225771 Effect of smoking and CYP2D6 polymorphisms on the extent of fluvoxamine-alprazolam interaction in patients with psychosomatic disease. 2009 Jul 3
12 18691982 Clinically relevant pharmacokinetic drug interactions with second-generation antidepressants: an update. 2008 Jul 1
13 18978520 Dose-dependent effect of the CYP2D6 genotype on the steady-state fluvoxamine concentration. 2008 Dec 4
14 17484519 Identification of human cytochrome P450 enzymes involved in the major metabolic pathway of fluvoxamine. 2007 Feb 2
15 17516189 Prolonged anticholinergic delirium following antihistamine overdose. 2007 Jun 1
16 16205777 Polymorphisms in the 5-hydroxytryptamine 2A receptor and CytochromeP4502D6 genes synergistically predict fluvoxamine-induced side effects in japanese depressed patients. 2006 Apr 6
17 16226034 Effect of fluvoxamine on plasma risperidone concentrations in patients with schizophrenia. 2005 Dec 2
18 15199661 Some aspects of genetic polymorphism in the biotransformation of antidepressants. 2004 Jan-Feb 1
19 12610741 CYP2D6*10 alleles do not determine plasma fluvoxamine concentration/dose ratio in Japanese subjects. 2003 Feb 1
20 12618595 Regeneration of serotonin from 5-methoxytryptamine by polymorphic human CYP2D6. 2003 Mar 1
21 12883230 Effects of the CYP 2D6 genotype and cigarette smoking on the steady-state plasma concentrations of fluvoxamine and its major metabolite fluvoxamino acid in Japanese depressed patients. 2003 Aug 1
22 14703714 Metabolic drug interactions with new psychotropic agents. 2003 Oct 1
23 11876575 Selective serotonin reuptake inhibitors and cytochrome P-450 mediated drug-drug interactions: an update. 2002 Feb 1
24 11907488 Low daily 10-mg and 20-mg doses of fluvoxamine inhibit the metabolism of both caffeine (cytochrome P4501A2) and omeprazole (cytochrome P4502C19). 2002 Mar 1
25 11519155 [Pharmacokinetics and drug interactions of antidepressive agents]. 2001 Aug 1
26 11791895 The major fluvoxamine metabolite in urine is formed by CYP2D6. 2001 Nov 5
27 10774624 Is therapeutic drug monitoring a case for optimizing clinical outcome and avoiding interactions of the selective serotonin reuptake inhibitors? 2000 Apr 1
28 10917404 Effect of selective serotonin reuptake inhibitors on the oxidative metabolism of propafenone: in vitro studies using human liver microsomes. 2000 Aug 1
29 10954064 Low dosage of levomepromazine did not increase plasma concentrations of fluvoxamine. 2000 Jul 2
30 11085201 Fluvoxamine. An updated review of its use in the management of adults with anxiety disorders. 2000 Oct 1
31 10051063 Therapeutic drug monitoring of risperidone using a new, rapid HPLC method: reappraisal of interindividual variability factors. 1999 Feb 1
32 10211917 CYP2D6 status of extensive metabolizers after multiple-dose fluoxetine, fluvoxamine, paroxetine, or sertraline. 1999 Apr 1
33 10471171 Metabolic interactions of central nervous system medications and selective serotonin reuptake inhibitors. 1999 May 1
34 9617978 Determinants of interindividual variability and extent of CYP2D6 and CYP1A2 inhibition by paroxetine and fluvoxamine in vivo. 1998 Jun 6
35 9757149 Effect of fluvoxamine therapy on the activities of CYP1A2, CYP2D6, and CYP3A as determined by phenotyping. 1998 Sep 4
36 9817620 Differences in interactions of SSRIs. 1998 Sep 1
37 9174682 Relationship between fluvoxamine pharmacokinetics and CYP2D6/CYP2C19 phenotype polymorphisms. 1997 3
38 9184622 Clinical pharmacokinetics of fluvoxamine: applications to dosage regimen design. 1997 1
39 10950475 Fluvoxamine and fluoxetine do not interact in the same way with the metabolism of the enantiomers of methadone. 1997 Apr 1
40 8823236 Disposition of fluvoxamine in humans is determined by the polymorphic CYP2D6 and also by the CYP1A2 activity. 1996 Aug 3
41 8838442 Venlafaxine oxidation in vitro is catalysed by CYP2D6. 1996 Feb 1
42 8880055 Dose-dependent inhibition of CYP1A2, CYP2C19 and CYP2D6 by citalopram, fluoxetine, fluvoxamine and paroxetine. 1996 3
43 8885123 Bupropion plasma levels and CYP2D6 phenotype. 1996 Oct 2
44 8968657 Pharmacokinetic-pharmacodynamic relationship of the selective serotonin reuptake inhibitors. 1996 Dec 2
45 8986013 Non-response to citalopram in depressive patients: pharmacokinetic and clinical consequences of a fluvoxamine augmentation. 1996 Dec 1
46 7622807 Comparative pharmacokinetics of selective serotonin reuptake inhibitors: a look behind the mirror. 1995 Mar 1
47 8567194 Cytochrome P450 monooxygenases and interactions of psychotropic drugs: a five-year update. 1995 1
48 8587855 Antidepressant drug interactions and the cytochrome P450 system: a critical appraisal. 1995 Nov-Dec 1
49 8685072 Fluvoxamine and fluoxetine: interaction studies with amitriptyline, clomipramine and neuroleptics in phenotyped patients. 1995 Jun 1
50 8846617 Overview of the pharmacokinetics of fluvoxamine. 1995 2