Daunorubicin

carbonyl reductase 1 ; Homo sapiens







15 Article(s)
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1 32588086 Interactions of antileukemic drugs with daunorubicin reductases: could reductases affect the clinical efficacy of daunorubicin chemoregimens? 2020 Sep 2
2 32621953 The epigallocatechin gallate derivative Y6 reduces the cardiotoxicity and enhances the efficacy of daunorubicin against human hepatocellular carcinoma by inhibiting carbonyl reductase 1 expression. 2020 Oct 28 2
3 30849340 Potent inhibition of human carbonyl reductase 1 (CBR1) by the prenylated chalconoid xanthohumol and its related prenylflavonoids isoxanthohumol and 8-prenylnaringenin. 2019 May 25 1
4 25541467 Curcumin is a tight-binding inhibitor of the most efficient human daunorubicin reductase--Carbonyl reductase 1. 2015 Jun 5 2
5 23295225 S-nitrosoglutathione covalently modifies cysteine residues of human carbonyl reductase 1 and affects its activity. 2013 Feb 25 1
6 22562609 Carbonyl reductase 1 expression influences daunorubicin metabolism in acute myeloid leukemia. 2012 Dec 13
7 22982121 Understanding the binding of daunorubicin and doxorubicin to NADPH-dependent cytosolic reductases by computational methods. 2012 Oct 2
8 20670211 Daunorubicin metabolism in leukemic cells isolated from patients with acute myeloid leukemia. 2010 Dec 1
9 20683966 Carbonyl reductase 1 as a novel target of (-)-epigallocatechin gallate against hepatocellular carcinoma. 2010 Aug 2
10 20729274 Expression of the anthracycline-metabolizing enzyme carbonyl reductase 1 in hearts from donors with Down syndrome. 2010 Dec 1
11 19204081 Two nonsynonymous single nucleotide polymorphisms of human carbonyl reductase 1 demonstrate reduced in vitro metabolism of daunorubicin and doxorubicin. 2009 May 1
12 18449627 Inhibition of polymorphic human carbonyl reductase 1 (CBR1) by the cardioprotectant flavonoid 7-monohydroxyethyl rutoside (monoHER). 2008 Jul 3
13 18579125 Flavonoids as inhibitors of human carbonyl reductase 1. 2008 Jul 30 2
14 17344335 A functional genetic polymorphism on human carbonyl reductase 1 (CBR1 V88I) impacts on catalytic activity and NADPH binding affinity. 2007 Jun 6
15 7553643 Protection against daunorubicin cytotoxicity by expression of a cloned human carbonyl reductase cDNA in K562 leukemia cells. 1995 Oct 15 7