Prostaglandins

carbonyl reductase 1 ; Homo sapiens







68 Article(s)
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1 32917645 Inflammation Modulation by Vitamin D and Calcium in the Morphologically Normal Colorectal Mucosa of Patients with Colorectal Adenoma in a Clinical Trial. 2021 Jan 1
2 34655851 Recent advances in studies of 15-PGDH as a key enzyme for the degradation of prostaglandins. 2021 Dec 5
3 34876851 Overexpression of 15-Hydroxyprostaglandin Dehydrogenase Inhibits A549 Lung Adenocarcinoma Cell Growth via Inducing Cell Cycle Arrest and Inhibiting Epithelial-Mesenchymal Transition. 2021 2
4 30931980 miR-21-mediated regulation of 15-hydroxyprostaglandin dehydrogenase in colon cancer. 2019 Apr 1 1
5 29224225 Downregulation of 15-hydroxyprostaglandin dehydrogenase by interleukin-1β from activated macrophages leads to poor prognosis in pancreatic cancer. 2018 Feb 2
6 29249255 Reduced Expression of Hydrogen Sulfide-Generating Enzymes Down-Regulates 15-Hydroxyprostaglandin Dehydrogenase in Chorion during Term and Preterm Labor. 2018 Jan 1
7 29414038 Investigation of 15-hydroxyprostaglandin dehydrogenase catalytic reaction mechanism by molecular dynamics simulations. 2018 Mar 1
8 29796776 Role of dihydroartemisinin in regulating prostaglandin E2 synthesis cascade and inflammation in endothelial cells. 2018 Nov 1
9 30248390 Smoking alters hydroxyprostaglandin dehydrogenase expression in fetal membranes. 2018 Dec 1
10 25450232 15-Oxoeicosatetraenoic acid is a 15-hydroxyprostaglandin dehydrogenase-derived electrophilic mediator of inflammatory signaling pathways. 2015 Jun 5 2
11 24838973 Inactivating mutation in the prostaglandin transporter gene, SLCO2A1, associated with familial digital clubbing, colon neoplasia, and NSAID resistance. 2014 Aug 1
12 25773924 15-Deoxy-Δ12,14-prostaglandin J2 induces expression of 15-hydroxyprostaglandin dehydrogenase through Elk-1 activation in human breast cancer MDA-MB-231 cells. 2014 Oct 1
13 23247010 Regulation of human carbonyl reductase 1 (CBR1, SDR21C1) gene by transcription factor Nrf2. 2013 Feb 25 3
14 23717544 Genetic variation in 15-hydroxyprostaglandin dehydrogenase and colon cancer susceptibility. 2013 2
15 22213326 Correlation of prostaglandin metabolizing enzymes and serum PGE2 levels with vitamin D receptor and serum 25(OH)2D3 levels in breast and ovarian cancer. 2012 Jan 2
16 22553128 Prostaglandin transporter mutations cause pachydermoperiostosis with myelofibrosis. 2012 Aug 2
17 21178489 ERG oncogene modulates prostaglandin signaling in prostate cancer cells. 2011 Feb 15 2
18 21426412 Primary hypertrophic osteoarthropathy with digital clubbing and palmoplantar hyperhidrosis caused by 15-PGHD/HPGD loss-of-function mutations. 2011 Jun 1
19 21763448 Regulation of 15-hydroxyprostaglandin dehydrogenase (15-PGDH) by non-steroidal anti-inflammatory drugs (NSAIDs). 2011 Nov 1
20 22020925 Prostaglandin catabolic enzymes as tumor suppressors. 2011 Dec 1
21 20304053 Expression of vitamin D receptor (VDR), cyclooxygenase-2 (COX-2) and 15-hydroxyprostaglandin dehydrogenase (15-PGDH) in benign and malignant ovarian tissue and 25-hydroxycholecalciferol (25(OH2)D3) and prostaglandin E2 (PGE2) serum level in ovarian cancer patients. 2010 Jul 2
22 20615530 Seminal plasma affects prostaglandin synthesis in the porcine oviduct. 2010 Oct 15 2
23 21072165 High-affinity inhibitors of human NAD-dependent 15-hydroxyprostaglandin dehydrogenase: mechanisms of inhibition and structure-activity relationships. 2010 Nov 2 2
24 21735612 Potent and selective inhibitors of NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (HPGD) 2010 3
25 19501039 15-Hydroxyprostaglandin dehydrogenase (15-PGDH) is up-regulated by flurbiprofen and other non-steroidal anti-inflammatory drugs in human colon cancer HT29 cells. 2009 Jul 15 1
26 19667157 Prostaglandin metabolizing enzymes in correlation with vitamin D receptor in benign and malignant breast cell lines. 2009 Sep 1
27 18212353 Opposite effect of phorbol ester PMA on PTGS2 and PGDH mRNA expression in human chorion trophoblast cells. 2008 Jan 1
28 18325997 Differential regulation of prostaglandin production mediated by corticotropin-releasing hormone receptor type 1 and type 2 in cultured human placental trophoblasts. 2008 Jun 1
29 18493841 Different functions between human monomeric carbonyl reductase 3 and carbonyl reductase 1. 2008 Aug 2
30 18639206 Effect of calcium ionophore A23187 on prostaglandin synthase type 2 and 15-hydroxy-prostaglandin dehydrogenase expression in human chorion trophoblast cells. 2008 Nov 1
31 18757412 Nonsteroidal anti-inflammatory drugs suppress glioma via 15-hydroxyprostaglandin dehydrogenase. 2008 Sep 1 1
32 18826943 Human carbonyl reductase 1 is an S-nitrosoglutathione reductase. 2008 Dec 19 2
33 19034772 Suppression of invasive properties of colorectal carcinoma SW480 cells by 15-hydroxyprostaglandin dehydrogenase gene. 2008 Nov 1
34 19108014 Decreased expression of 15-hydroxyprostaglandin dehydrogenase in gastric carcinomas. 2008 Dec 31 1
35 17182827 Calcitriol and genistein actions to inhibit the prostaglandin pathway: potential combination therapy to treat prostate cancer. 2007 Jan 1
36 17481556 15-hydroxyprostaglandin dehydrogenase (15-PGDH) and lung cancer. 2007 May 2
37 17546626 The cyclooxygenase-2-mediated prostaglandin signaling is causally related to epithelial carcinogenesis. 2007 Aug 1
38 17636240 15-Hydroxyprostaglandin dehydrogenase protein expression in human fetal membranes with and without subclinical inflammation. 2007 Apr 1
39 16533162 NAD+-linked 15-hydroxyprostaglandin dehydrogenase: structure and biological functions. 2006 3
40 16631754 Molecular pathology of breast apocrine carcinomas: a protein expression signature specific for benign apocrine metaplasia. 2006 May 22 1
41 16828555 Role of glutamine 148 of human 15-hydroxyprostaglandin dehydrogenase in catalytic oxidation of prostaglandin E2. 2006 Oct 1 1
42 16880406 15-Hydroxyprostaglandin dehydrogenase is an in vivo suppressor of colon tumorigenesis. 2006 Aug 8 2
43 16885386 15-hydroxyprostaglandin dehydrogenase is a tumor suppressor of human breast cancer. 2006 Aug 1 2
44 16997128 15-Hydroxyprostaglandin-dehydrogenase is involved in anti-proliferative effect of non-steroidal anti-inflammatory drugs COX-1 inhibitors on a human medullary thyroid carcinoma cell line. 2006 Oct 1
45 15581601 Key NAD+-binding residues in human 15-hydroxyprostaglandin dehydrogenase. 2005 Jan 15 1
46 16103446 Carbonyl reductase expression and its clinical significance in non-small-cell lung cancer. 2005 Aug 2
47 16140963 Regulation of prostaglandin metabolism by calcitriol attenuates growth stimulation in prostate cancer cells. 2005 Sep 1 1
48 14718596 Suppression of 15-hydroxyprostaglandin dehydrogenase messenger RNA concentration, protein expression, and enzymatic activity during human ureteral obstruction. 2004 Apr 1
49 14749354 Synergistic induction of the nicotinamide adenine dinucleotide-linked 15-hydroxyprostaglandin dehydrogenase by an androgen and interleukin-6 or forskolin in human prostate cancer cells. 2004 May 4
50 15531523 Regulation of 15-hydroxyprostaglandin dehydrogenase (PGDH) gene activity, messenger ribonucleic acid processing, and protein abundance in the human chorion in late gestation and labor. 2004 Nov 2