| 1 |
35405267 | Reducing the off-target endocrinologic adverse effects of azole antifungals-can it be done? | 2022 May |
1 |
| 2 |
35471041 | The Set1 Histone H3K4 Methyltransferase Contributes to Azole Susceptibility in a Species-Specific Manner by Differentially Altering the Expression of Drug Efflux Pumps and the Ergosterol Gene Pathway. | 2022 May 17 |
4 |
| 3 |
32065093 | Design and Synthesis of New Antifungals Based on N-Un-substituted Azoles as 14α Demethylase Inhibitor. | 2021 |
1 |
| 4 |
32347094 | Discovery of Novel Fungal Lanosterol 14α-Demethylase (CYP51)/Histone Deacetylase Dual Inhibitors to Treat Azole-Resistant Candidiasis. | 2020 May 28 |
3 |
| 5 |
31310805 | Isavuconazole and voriconazole inhibition of sterol 14α-demethylases (CYP51) from Aspergillus fumigatus and Homo sapiens. | 2019 Oct |
1 |
| 6 |
29263059 | Impact of Homologous Resistance Mutations from Pathogenic Yeast on Saccharomyces cerevisiae Lanosterol 14α-Demethylase. | 2018 Mar |
2 |
| 7 |
28180188 | Imidazoles Induce Reactive Oxygen Species in Mycobacterium tuberculosis Which Is Not Associated with Cell Death. | 2017 Jan 31 |
1 |
| 8 |
26482310 | Activity of Isavuconazole and Other Azoles against Candida Clinical Isolates and Yeast Model Systems with Known Azole Resistance Mechanisms. | 2016 Jan |
1 |
| 9 |
27436465 | Amino acid substitutions in Erg11p of azole-resistant Candida glabrata: Possible effective substitutions and homology modelling. | 2016 Jun |
1 |
| 10 |
24298976 | Alterations in the predicted regulatory and coding regions of the sterol 14α-demethylase gene (CYP51) confer decreased azole sensitivity in the oilseed rape pathogen Pyrenopeziza brassicae. | 2014 Jun |
4 |
| 11 |
25512882 | Structural basis for heterogeneous phenotype of ERG11 dependent Azole resistance in C.albicans clinical isolates. | 2014 |
3 |
| 12 |
23221625 | Mechanisms of azole resistance in 52 clinical isolates of Candida tropicalis in China. | 2013 Apr |
5 |
| 13 |
23442154 | Characterization of the sterol 14α-demethylases of Fusarium graminearum identifies a novel genus-specific CYP51 function. | 2013 May |
1 |
| 14 |
23480635 | Erg11 mutations associated with azole resistance in clinical isolates of Candida albicans. | 2013 Jun |
3 |
| 15 |
23979758 | Azole resistance in Cryptococcus gattii from the Pacific Northwest: Investigation of the role of ERG11. | 2013 Nov |
7 |
| 16 |
22615293 | An integrated approach for identification and target validation of antifungal compounds active against Erg11p. | 2012 Aug |
4 |
| 17 |
21478305 | Impact of recently emerged sterol 14{alpha}-demethylase (CYP51) variants of Mycosphaerella graminicola on azole fungicide sensitivity. | 2011 Jun |
3 |
| 18 |
20305029 | Heterologous expression of mutated eburicol 14alpha-demethylase (CYP51) proteins of Mycosphaerella graminicola to assess effects on azole fungicide sensitivity and intrinsic protein function. | 2010 May |
3 |
| 19 |
19015352 | Abc1p is a multidrug efflux transporter that tips the balance in favor of innate azole resistance in Candida krusei. | 2009 Feb |
4 |
| 20 |
18694951 | Differential azole antifungal efficacies contrasted using a Saccharomyces cerevisiae strain humanized for sterol 14 alpha-demethylase at the homologous locus. | 2008 Oct |
2 |
| 21 |
18853217 | Expression and characterization of CYP51, the ancient sterol 14-demethylase activity for cytochromes P450 (CYP), in the white-rot fungus Phanerochaete chrysosporium. | 2008 Dec |
2 |
| 22 |
16964330 | Antifungal agents: mode of action in yeast cells. | 2006 Jun |
2 |
| 23 |
17073780 | CYP121, CYP51 and associated redox systems in Mycobacterium tuberculosis: towards deconvoluting enzymology of P450 systems in a human pathogen. | 2006 Dec |
2 |
| 24 |
15155210 | Application of real-time quantitative PCR to molecular analysis of Candida albicans strains exhibiting reduced susceptibility to azoles. | 2004 Jun |
1 |
| 25 |
15530358 | Estriol bound and ligand-free structures of sterol 14alpha-demethylase. | 2004 Nov |
2 |
| 26 |
12748589 | [Azole resistance in Candida spp]. | 2003 |
5 |
| 27 |
12366848 | Antifungal activity in Saccharomyces cerevisiae is modulated by calcium signalling. | 2002 Oct |
1 |
| 28 |
12477804 | ROX1 and ERG regulation in Saccharomyces cerevisiae: implications for antifungal susceptibility. | 2002 Dec |
1 |
| 29 |
11356139 | An old activity in the cytochrome P450 superfamily (CYP51) and a new story of drugs and resistance. | 2001 May |
1 |
| 30 |
11377375 | Azole-antifungal binding to a novel cytochrome P450 from Mycobacterium tuberculosis: implications for treatment of tuberculosis. | 2001 Jun 15 |
2 |
| 31 |
10445042 | Molecular modelling of lanosterol 14 alpha-demethylase (CYP51) from Saccharomyces cerevisiae via homology with CYP102, a unique bacterial cytochrome P450 isoform: quantitative structure-activity relationships (QSARs) within two related series of antifungal azole derivatives. | 1999 |
4 |
| 32 |
10592714 | [Adherence and invasion-two pathogenicity factors in bacterial and fungal pathogens]. | 1999 |
1 |