entacapone

catechol-O-methyltransferase ; Homo sapiens







168 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
101 11440283 Entacapone: a catechol-O-methyltransferase inhibitor for the adjunctive treatment of Parkinson's disease. 2001 Jun 2
102 11498717 L-dopa induces dyskinesia in normal monkeys: behavioural and pharmacokinetic observations. 2001 Aug 2
103 11586115 Long-term comparative experience with tolcapone and entacapone in advanced Parkinson's disease. 2001 Sep-Oct 1
104 10703007 [Inhibition of catechol-O-methyltransferase. Optimizing dopaminergic therapy in idiopathic Parkinson syndrome with entacapone]. 2000 Feb 1
105 10733264 Comparative tolerability of the newer generation antiparkinsonian agents. 2000 Jan 1
106 10766888 The catechol-O-methyltransferase (COMT) inhibitor entacapone enhances the pharmacokinetic and clinical response to Sinemet CR in Parkinson's disease. 2000 May 4
107 10858804 The role of entacapone in the management of Parkinson's disease. 2000 Apr 1
108 10882160 Clinical pharmacology, therapeutic use and potential of COMT inhibitors in Parkinson's disease. 2000 Jun 2
109 10900396 Entacapone and selegiline with L-dopa in patients with Parkinson's disease: an interaction study. 2000 Oct 1 2
110 10981253 Entacapone. 2000 Sep 2
111 11038168 The specificity of glucuronidation of entacapone and tolcapone by recombinant human UDP-glucuronosyltransferases. 2000 Nov 1
112 11147507 Issues important for rational COMT inhibition. 2000 1
113 11147508 Effect of COMT inhibition on the pharmacokinetics and pharmacodynamics of levodopa in parkinsonian patients. 2000 1
114 11147509 Benefits of COMT inhibitors in levodopa-treated parkinsonian patients: results of clinical trials. 2000 2
115 11147510 COMT inhibitors and liver toxicity. 2000 1
116 11147511 Practical issues with COMT inhibitors in Parkinson's disease. 2000 2
117 11147512 The place of COMT inhibitors in the armamentarium of drugs for the treatment of Parkinson's disease. 2000 1
118 10027643 Separation of the glucuronides of entacapone and its (Z)-isomer in urine by micellar electrokinetic capillary chromatography. 1999 Jan 8 2
119 10220913 Micellar electrokinetic capillary chromatography method for direct determination of glucuronides of entacapone and its (Z)-isomer in human urine. 1999 Mar 19 2
120 10229966 [Entacapone++ : a new catechol-O-methyltransferase inhibitor which improves the response to levodopa in patients with Parkinson disease and fluctuating motor function]. 1999 Mar 1-15 1
121 10363328 [Entacapone: is it useful as complimentary treatment with levodopa?]. 1999 Apr 16-30 4
122 10410761 COMT inhibition with entacapone in the treatment of Parkinson's disease. 1999 1
123 10439935 Entacapone. A review of its use in Parkinson's disease. 1999 Jul 2
124 10451758 COMT inhibitors in Parkinson's disease. 1999 Aug 1
125 10492060 Pharmacokinetics of oral entacapone after frequent multiple dosing and effects on levodopa disposition. 1999 Aug 3
126 10555945 Interventions to achieve tonic exposure to levodopa: delaying or preventing the onset of motor complications. 1999 Nov 1
127 10570622 [Inhibition of the COMPT with entacapone in the treatment of motor fluctuations in Parkinson disease]. 1999 Aug-Sep 4
128 11503812 Entacapone: new preparation. Comparative data are lacking. 1999 Dec 1
129 12973467 Perspectives in the treatment of Parkinson's disease: COMT inhibitors open up new treatment strategies. 1999 Sep 1
130 15992091 Entacapone, a catechol-O-methyltransferase inhibitor for treating Parkinson's disease: review and current status. 1999 Apr 3
131 9591516 COMT inhibition: a new treatment strategy for Parkinson's disease. 1998 May 2
132 9591519 Influence of COMT inhibition on levodopa pharmacology and therapy. 1998 May 1
133 9633684 Extending levodopa action: COMT inhibition. 1998 Jun 3
134 9681662 Catechol-O-methyltransferase: variation in enzyme activity and inhibition by entacapone and tolcapone. 1998 May 4
135 9808337 COMT inhibition in the treatment of Parkinson's disease. 1998 Nov 3
136 9818851 Entacapone enhances the response to levodopa in parkinsonian patients with motor fluctuations. Nomecomt Study Group. 1998 Nov 2
137 9232524 Iron(III)-chelating properties of the novel catechol O-methyltransferase inhibitor entacapone in aqueous solution. 1997 Jul 3
138 9251066 Simultaneous MAO-B and COMT inhibition in L-Dopa-treated patients with Parkinson's disease. 1997 Jul 1
139 9337447 New pharmacotherapy for Parkinson's disease. 1997 Oct 2
140 9372556 Striatal 6-[18F]fluorodopa accumulation after combined inhibition of peripheral catechol-O-methyltransferase and monoamine oxidase type B: differing response in relation to presynaptic dopaminergic dysfunction. 1997 Dec 1
141 9392574 Entacapone improves motor fluctuations in levodopa-treated Parkinson's disease patients. Parkinson Study Group. 1997 Nov 1
142 8558148 Entacapone prolongs levodopa response in a one month double blind study in parkinsonian patients with levodopa related fluctuations. 1996 Jan 1
143 8612391 Simultaneous inhibition of catechol-O-methyltransferase and monoamine oxidase A: effects on hemodynamics and catecholamine metabolism in healthy volunteers. 1996 Apr 2
144 8726541 Effect of one month's treatment with peripherally acting catechol-O-methyltransferase inhibitor, entacapone, on pharmacokinetics and motor response to levodopa in advanced parkinsonian patients. 1996 Jun 1
145 8738181 Validation of assay of catechol-O-methyltransferase activity in human erythrocytes. 1996 Mar 2
146 8784230 Fluorodopa positron emission tomography with an inhibitor of catechol-O-methyltransferase: effect of the plasma 3-O-methyldopa fraction on data analysis. 1996 Sep 2
147 8836934 COMT inhibition by entacapone does not affect growth hormone or prolactin secretion in healthy volunteers. 1996 3
148 9010698 Simultaneous inhibition of catecholamine-O-methylation by entacapone and neuronal uptake by imipramine: lack of interactions. 1996 2
149 7648772 The effect of entacapone on the disposition and hemodynamic effects of intravenous isoproterenol and epinephrine. 1995 Aug 3
150 8665534 Effect of entacapone, a COMT inhibitor, on the pharmacokinetics and metabolism of levodopa after administration of controlled-release levodopa-carbidopa in volunteers. 1995 Feb 4