Morphine

catechol-O-methyltransferase ; Homo sapiens







32 Article(s)
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1 34015137 Innate Immune and Neuronal Genetic Markers Are Highly Predictive of Postoperative Pain and Morphine Patient-Controlled Analgesia Requirements in Indian but Not Chinese or Malay Hysterectomy Patients. 2021 Nov 26 1
2 31967515 OPRM1 and COMT polymorphisms: implications on postoperative acute, chronic and experimental pain after cardiac surgery. 2020 Feb 1
3 30709768 Morphine biotransformation genes and neonatal clinical factors predicted behaviour problems in very preterm children at 18 months. 2019 Feb 1
4 29870475 Severe and persistent morphine-induced respiratory depression associated with ATP-Binding Cassette Subfamily B Member 1 and catechol-O-methyltransferase genetic defects: A case report. 2018 Jul 1
5 28084056 Genetic Influences of OPRM1, OPRD1 and COMT on Morphine Analgesia in a Multi-Modal, Multi-Tissue Human Experimental Pain Model. 2017 Jul 4
6 28928973 Prospective replication study implicates the catechol-O-methyltransferase Val158Met polymorphism as a biomarker for the response to morphine in patients with cancer. 2017 Oct 5
7 28985716 Selection of opioids for cancer-related pain using a biomarker: a randomized, multi-institutional, open-label trial (RELIEF study). 2017 Oct 6 5
8 29259946 Genetic Analysis of Mu and Kappa Opioid Receptor and COMT Enzyme in Cancer Pain Tunisian Patients Under Opioid Treatment. 2017 Dec 1
9 25963335 Common variants of catechol-O-methyltransferase influence patient-controlled analgesia usage and postoperative pain in patients undergoing total hysterectomy. 2016 Apr 1
10 26902643 Human Genetic Variability Contributes to Postoperative Morphine Consumption. 2016 May 1
11 27288213 Association of the OPRM1 and COMT genes' polymorphisms with the efficacy of morphine in Tunisian cancer patients: Impact of the high genetic heterogeneity in Tunisia? 2016 Oct 1
12 26678969 Clinical Implications of Opioid Pharmacogenomics in Patients With Cancer. 2015 Oct 1
13 24533707 Genetics of pain perception, COMT and postoperative pain management in children. 2014 Feb 1
14 25155931 Rescue morphine in mechanically ventilated newborns associated with combined OPRM1 and COMT genotype. 2014 Jul 4
15 23210659 The Val158Met polymorphism of the COMT gene is associated with increased pain sensitivity in morphine-treated patients undergoing a painful procedure after cardiac surgery. 2013 Jun 3
16 23686330 Genetic variability at COMT but not at OPRM1 and UGT2B7 loci modulates morphine analgesic response in acute postoperative pain. 2013 Sep 4
17 23773341 An opposite-direction modulation of the COMT Val158Met polymorphism on the clinical response to intrathecal morphine and triptans. 2013 Oct 3
18 22293824 Expression changes in arrestin β 1 and genetic variation in catechol-O-methyltransferase are biomarkers for the response to morphine treatment in cancer patients. 2012 May 5
19 21127283 Combined catechol-O-methyltransferase and mu-opioid receptor gene polymorphisms affect morphine postoperative analgesia and central side effects. 2011 Feb 3
20 19912274 Dopamine, morphine, and nitric oxide: an evolutionary signaling triad. 2010 Jun 1
21 20150871 Variations in critical morphine biosynthesis genes and their potential to influence human health. 2010 1
22 22371762 Catechol-O-methyltransferase: potential relationship to idiopathic hypertension. 2010 Jun 30 2
23 17573783 Endogenous morphine signaling via nitric oxide regulates the expression of CYP2D6 and COMT: autocrine/paracrine feedback inhibition. 2008 Mar 4
24 17722074 Pharmacogenetics of morphine: Potential implications in sickle cell disease. 2008 Mar 1
25 18257092 Genetic variation and response to morphine in cancer patients: catechol-O-methyltransferase and multidrug resistance-1 gene polymorphisms are associated with central side effects. 2008 Mar 15 2
26 18370847 Genetic mutations that prevent pain: implications for future pain medication. 2008 Feb 1
27 19094200 Genetic variation in the catechol-O-methyltransferase (COMT) gene and morphine requirements in cancer patients with pain. 2008 Dec 18 3
28 17156920 Exploring joint effects of genes and the clinical efficacy of morphine for cancer pain: OPRM1 and COMT gene. 2007 Jul 5
29 17982691 Endogenous morphine synthetic pathway preceded and gave rise to catecholamine synthesis in evolution (Review). 2007 Dec 1
30 15927391 The Val158Met polymorphism of the human catechol-O-methyltransferase (COMT) gene may influence morphine requirements in cancer pain patients. 2005 Jul 4
31 16045647 Genetic variability and clinical efficacy of morphine. 2005 Aug 2
32 16215614 [Genetic variation-- important for the clinical effect of opioids?]. 2005 Oct 6 1