290 Article(s)Download |
PMID | Title | Pub. Year | #Total Relationships |
51 | 26295926 | Development of a physiologically based pharmacokinetic/pharmacodynamic model to identify mechanisms contributing to entacapone low bioavailability. | 2015 Dec | 2 |
52 | 24008922 | Influence of single nucleotide polymorphisms in COMT, MAO-A and BDNF genes on dyskinesias and levodopa use in Parkinson's disease. | 2014 | 1 |
53 | 24148813 | Brain and peripheral pharmacokinetics of levodopa in the cynomolgus monkey following administration of opicapone, a third generation nitrocatechol COMT inhibitor. | 2014 Feb | 1 |
54 | 24271646 | Effect of moderate liver impairment on the pharmacokinetics of opicapone. | 2014 Mar | 1 |
55 | 24716406 | Inhibition of catechol-o-methyltransferase (COMT) by myricetin, dihydromyricetin, and myricitrin. | 2014 Mar | 5 |
56 | 24770794 | Fewer fluctuations, higher maximum concentration and better motor response of levodopa with catechol-O-methyltransferase inhibition. | 2014 Nov | 8 |
57 | 24830331 | Entacapone reduces cortical activation in Parkinson's disease with wearing-off: a f-MRI study. | 2014 | 2 |
58 | 24925090 | Effect of opicapone and entacapone upon levodopa pharmacokinetics during three daily levodopa administrations. | 2014 Sep | 3 |
59 | 25154960 | Endothelial dysfunction and hyperhomocysteinemia in Parkinson's disease: flow-mediated dilation study. | 2014 Oct | 2 |
60 | 23206800 | Beneficial effects of natural phenolics on levodopa methylation and oxidative neurodegeneration. | 2013 Feb 25 | 3 |
61 | 23237479 | Effects of transcranial direct current stimulation (tDCS) on executive functions: influence of COMT Val/Met polymorphism. | 2013 Jul-Aug | 1 |
62 | 23948989 | Levodopa in the treatment of Parkinson's disease: current status and new developments. | 2013 Jan 1 | 1 |
63 | 23994933 | [Influence of levodopa, stalevo on dyskinesia in Parkinson's disease: STRIDE-PD study]. | 2013 | 1 |
64 | 24234932 | Association Between Catechol-O-Methyltransferase (COMT) Gene Polymorphisms, Parkinson's Disease, and Levodopa Efficacy. | 2013 Nov 15 | 3 |
65 | 24532988 | Pharmacogenetics of Parkinson's disease - through mechanisms of drug actions. | 2013 Dec | 1 |
66 | 22123108 | Bioanalytical chromatographic methods for the determination of catechol-O-methyltransferase inhibitors in rodents and human samples: a review. | 2012 Jan 13 | 2 |
67 | 22136069 | Intestinal levodopa infusion and COMT inhibition - a promising link. | 2012 Jun | 1 |
68 | 22136163 | Levodopa infusion combined with entacapone or tolcapone in Parkinson disease: a pilot trial. | 2012 Jun | 3 |
69 | 22483291 | Role of catechol-O-methyltransferase (COMT)-dependent processes in Parkinson's disease and L-DOPA treatment. | 2012 May | 4 |
70 | 22863920 | Effects of 3-O-methyldopa, L-3,4-dihydroxyphenylalanine metabolite, on locomotor activity and dopamine turnover in rats. | 2012 | 4 |
71 | 23020119 | Protective effects of L-dopa and carbidopa combined treatments on human catecholaminergic cells. | 2012 Nov | 4 |
72 | 23093014 | The catechol-O-methyltransferase and monoamine oxidase B polymorphisms and levodopa therapy in the Iranian patients with sporadic Parkinson's disease. | 2012 | 2 |
73 | 21164341 | Erythrocytes catechol-o-methyl transferase activity is up-regulated after a 3-month treatment by entacapone in parkinsonian patients. | 2011 Jan-Feb | 2 |
74 | 21280081 | The COMT Val158Met polymorphism affects the response to entacapone in Parkinson's disease: a randomized crossover clinical trial. | 2011 Jan | 5 |
75 | 21533995 | Inhibition of catechol-O-methyltransferase modifies acute homocysteine rise during repeated levodopa application in patients with Parkinson's disease. | 2011 Jun | 4 |
76 | 21538606 | Molecular recognition at the active site of catechol-O-methyltransferase (COMT): adenine replacements in bisubstrate inhibitors. | 2011 May 27 | 3 |
77 | 21738693 | Comparison of endothelial progenitor cells in Parkinson's disease patients treated with levodopa and levodopa/COMT inhibitor. | 2011 | 1 |
78 | 22053701 | Relationship between 3-O-methyldopa and the clinical effects of entacapone in advanced Parkinson's disease. | 2011 Sep | 2 |
79 | 22093536 | Pharmacological treatment and the prospect of pharmacogenetics in Parkinson's disease. | 2011 Dec | 1 |
80 | 25205926 | Cell based therapies in Parkinson's Disease. | 2011 Apr | 1 |
81 | 19676096 | Reduced 3-O-methyl-dopa levels in OCD patients and their unaffected parents is associated with the low activity M158 COMT allele. | 2010 Mar 5 | 1 |
82 | 19879254 | Entacapone, a catechol-O-methyltransferase inhibitor, improves the motor activity and dopamine content of basal ganglia in a rat model of Parkinson's disease induced by Japanese encephalitis virus. | 2010 Jan 14 | 1 |
83 | 19909787 | Impaired transmethylation potential in Parkinson's disease patients treated with L-Dopa. | 2010 Jan 14 | 2 |
84 | 20077469 | The effect of peripheral enzyme inhibitors on levodopa concentrations in blood and CSF. | 2010 Feb 15 | 1 |
85 | 20464572 | Effect of entacapone on plasma homocysteine levels in Parkinson's disease patients. | 2010 Oct | 2 |
86 | 20582993 | Initiating levodopa/carbidopa therapy with and without entacapone in early Parkinson disease: the STRIDE-PD study. | 2010 Jul | 1 |
87 | 20700524 | Dual beneficial effects of (-)-epigallocatechin-3-gallate on levodopa methylation and hippocampal neurodegeneration: in vitro and in vivo studies. | 2010 Aug 5 | 2 |
88 | 20812452 | [The effect of Stalevo-dosing on quality of life of Parkinsonian patients with wearing-off]. | 2010 Jul 30 | 1 |
89 | 20856911 | Therapeutic interventions and adjustments in the management of Parkinson disease: role of combined carbidopa/levodopa/entacapone (Stalevo). | 2010 Sep 7 | 2 |
90 | 21095456 | Introductory remarks: Catechol-O-methyltransferase inhibition--an innovative approach to enhance L-dopa therapy in Parkinson's disease with dual enzyme inhibition. | 2010 | 11 |
91 | 21095459 | Catechol-O-methyltransferase enzyme: cofactor S-adenosyl-L-methionine and related mechanisms. | 2010 | 1 |
92 | 21095461 | The chemistry of catechol-O-methyltransferase inhibitors. | 2010 | 2 |
93 | 21095462 | Toxicology and safety of COMT inhibitors. | 2010 | 2 |
94 | 21095464 | Problems with the present inhibitors and a relevance of new and improved COMT inhibitors in Parkinson's disease. | 2010 | 1 |
95 | 19056347 | Crystal structures of rat catechol-O-methyltransferase complexed with coumarine-based inhibitor. | 2009 Jan 16 | 2 |
96 | 19131039 | L-dopa therapy for Parkinson's disease: past, present, and future. | 2009 Jan | 2 |
97 | 19167259 | Pharmacologic treatment of advanced Parkinson's disease: a meta-analysis of COMT inhibitors and MAO-B inhibitors. | 2009 Aug | 1 |
98 | 19407449 | Levodopa: past, present, and future. | 2009 | 2 |
99 | 19538218 | Levodopa in the treatment of Parkinson's disease. | 2009 Sep | 1 |
100 | 19589043 | Levodopa/carbidopa/entacapone in Parkinson's disease. | 2009 Jul | 4 |