nitrocatechol

catechol-O-methyltransferase ; Homo sapiens







19 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 32108308 Design, synthesis and evaluation of 3-hydroxypyridin-4-ones as inhibitors of catechol-O-methyltransferase. 2021 May 3
2 33220276 Opicapone enhances the reversal of MPTP-induced Parkinson-like syndrome by levodopa in cynomolgus monkeys. 2021 Feb 5 1
3 34225162 The inhibition of catechol O-methyltransferase and monoamine oxidase by tetralone and indanone derivatives substituted with the nitrocatechol moiety. 2021 Sep 5
4 32299731 Evaluation of nitrocatechol chalcone and pyrazoline derivatives as inhibitors of catechol-O-methyltransferase and monoamine oxidase. 2020 Jun 15 5
5 32378542 Crystal Structure of Catechol O-Methyltransferase Complexed with Nitecapone. 2020 1
6 29697034 Nitrocatechol Derivatives of Chalcone as Inhibitors of Monoamine Oxidase and Catechol-O-Methyltransferase. 2018 5
7 23713800 Structure-based drug design of catechol-O-methyltransferase inhibitors for CNS disorders. 2014 Mar 1
8 24148818 Synergistic inhibition of lung cancer cell lines by (-)-epigallocatechin-3-gallate in combination with clinically used nitrocatechol inhibitors of catechol-O-methyltransferase. 2014 Feb 1
9 22860182 Characterization of non-nitrocatechol pan and isoform specific catechol-O-methyltransferase inhibitors and substrates. 2012 Feb 15 3
10 20334432 Discovery of a long-acting, peripherally selective inhibitor of catechol-O-methyltransferase. 2010 Apr 22 2
11 16618795 Comparative study of ortho- and meta-nitrated inhibitors of catechol-O-methyltransferase: interactions with the active site and regioselectivity of O-methylation. 2006 Jul 1
12 16335931 Synthesis and biological evaluation of a novel series of "ortho-nitrated" inhibitors of catechol-O-methyltransferase. 2005 Dec 15 1
13 12584150 Molecular modeling and metabolic studies of the interaction of catechol-O-methyltransferase and a new nitrocatechol inhibitor. 2003 Mar 4
14 12236793 Chemical synthesis and characterization of conjugates of a novel catechol-O-methyltransferase inhibitor. 2002 Sep-Oct 1
15 10882160 Clinical pharmacology, therapeutic use and potential of COMT inhibitors in Parkinson's disease. 2000 Jun 1
16 9633684 Extending levodopa action: COMT inhibition. 1998 Jun 3
17 8674740 Nitrocatechol derivatives as inhibitors of catechol-O-methyltransferase. 1996 Feb 1
18 7835624 General properties and clinical possibilities of new selective inhibitors of catechol O-methyltransferase. 1994 Sep 1
19 27520516 Clinical Potential of Catechol-OMethyltransferase (COMT) Inhibitors as Adjuvants in Parkinson's Disease. 1994 Mar 1