nebicapone

catechol-O-methyltransferase ; Homo sapiens







17 Article(s)
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PMID
Title
Pub. Year
#Total Relationships
1 22805229 A systematic review of catechol-0-methyltransferase inhibitors: efficacy and safety in clinical practice. 2012 Jul-Aug 1
2 20225994 Chronopharmacology of nebicapone, a new catechol-O-methyltransferase inhibitor. 2010 May 6
3 20642448 Pharmacokinetics, disposition, and metabolism of [14C]-nebicapone in humans. 2010 Aug 2
4 21095464 Problems with the present inhibitors and a relevance of new and improved COMT inhibitors in Parkinson's disease. 2010 1
5 19922897 Pharmacokinetic-pharmacodynamic interaction between nebicapone and controlled-release levodopa/benserazide: a single-center, Phase I, double-blind, randomized, placebo-controlled, four-way crossover study in healthy subjects. 2009 Oct 4
6 18303486 Effects of nebicapone on levodopa pharmacokinetics, catechol-O-methyltransferase activity, and motor fluctuations in patients with Parkinson disease. 2008 Jan-Feb 5
7 18679669 Effect of nebicapone on the pharmacokinetics and pharmacodynamics of warfarin in healthy subjects. 2008 Oct 1
8 18989992 Pharmacokinetic-pharmacodynamic interaction between nebicapone, a novel catechol-o-methyltransferase inhibitor, and controlled-release levodopa/carbidopa 200 mg/50 mg : randomized, double-blind, placebo-controlled, crossover study in healthy subjects. 2008 6
9 17894650 Catechol-O-methyltransferase and its inhibitors in Parkinson's disease. 2007 Fall 1
10 16790555 Human metabolism of nebicapone (BIA 3-202), a novel catechol-o-methyltransferase inhibitor: characterization of in vitro glucuronidation. 2006 Nov 3
11 15090932 Pharmacokinetic-pharmacodynamic interaction between BIA 3-202, a novel COMT inhibitor, and levodopa/carbidopa. 2004 Jan-Feb 1
12 12584150 Molecular modeling and metabolic studies of the interaction of catechol-O-methyltransferase and a new nitrocatechol inhibitor. 2003 Mar 1
13 12787259 Catechol-O-methyltransferase inhibition in erythrocytes and liver by BIA 3-202 (1-[3,4-dibydroxy-5-nitrophenyl]-2-phenyl-ethanone). 2003 Jun 2
14 12848585 Pharmacokinetics and pharmacodynamics of BIA 3-202, a novel COMT inhibitor, during first administration to humans. 2003 2
15 14517707 Pharmacokinetic-pharmacodynamic interaction between BIA 3-202, a novel COMT inhibitor, and levodopa/benserazide. 2003 Nov 3
16 14615471 Pharmacokinetic and pharmacodynamic profiles of BIA 3-202, a novel catechol-O-methyltransferase (COMT) inhibitor, during multiple-dose administration to healthy subjects. 2003 Dec 1
17 12236793 Chemical synthesis and characterization of conjugates of a novel catechol-O-methyltransferase inhibitor. 2002 Sep-Oct 4