Deoxycytidine

deoxycytidine kinase ; Homo sapiens







28 Article(s)
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1 24048768 Metabolism, mechanism of action and sensitivity profile of fluorocyclopentenylcytosine (RX-3117; TV-1360). 2013 Dec 1
2 22571666 Recent advances in thymidine kinase 2 (TK2) inhibitors and new perspectives for potential applications. 2012 2
3 20066470 Antiproliferative activity, mechanism of action and oral antitumor activity of CP-4126, a fatty acid derivative of gemcitabine, in in vitro and in vivo tumor models. 2011 Jun 2
4 19959816 Novel potent inhibitors of deoxycytidine kinase identified and compared by multiple assays. 2010 Jan 1
5 20436341 Staurosporine increases toxicity of gemcitabine in non-small cell lung cancer cells: role of protein kinase C, deoxycytidine kinase and ribonucleotide reductase. 2010 Jul 1
6 18361501 Systematic exploration of active site mutations on human deoxycytidine kinase substrate specificity. 2008 Apr 22 1
7 18058539 Troxacitabine prodrugs for pancreatic cancer. 2007 1
8 17065050 Cellular resistance against troxacitabine in human cell lines and pediatric patient acute myeloid leukemia blast cells. 2006 1
9 15571257 Immunocytochemical detection of deoxycytidine kinase in pediatric malignancies in relation to in vitro cytarabine sensitivity. 2004 Oct 1
10 12799644 Increased sensitivity to gemcitabine of P-glycoprotein and multidrug resistance-associated protein-overexpressing human cancer cell lines. 2003 Jun 16 1
11 12808445 Structure of human dCK suggests strategies to improve anticancer and antiviral therapy. 2003 Jul 1
12 12127861 Determinants of resistance to 2',2'-difluorodeoxycytidine (gemcitabine). 2002 Feb 1
13 11562990 The NMR conformation study of the complexes of deoxycytidine kinase (dCK) and 2'-deoxycytidine/2'-deoxyadenosine. 2001 Apr-Jul 1
14 10673748 2-Chloro-2'-deoxyadenosine induces apoptosis through the Fas/Fas ligand pathway in human leukemia cell line MOLT-4. 2000 Feb 1
15 10961690 Cytostatic and cytotoxic effects of (E)-2'-deoxy-2'-(fluoromethylene)-cytidine on a solid tumor and a leukemia cell line. 2000 1
16 9658118 Human thymidine kinase can functionally replace herpes simplex virus type 1 thymidine kinase for viral replication in mouse sensory ganglia and reactivation from latency upon explant. 1998 Aug 1
17 9096697 Differential effect of GM-CSF pretreatment on intracellular Ara-C metabolism in normal bone marrow mononuclear cells vs acute myeloid leukemia (AML) blasts. 1997 Apr 1
18 9145844 Modulation of the metabolism of beta-L-(-)-2',3'-dideoxy-3'-thiacytidine by thymidine, fludarabine, and nitrobenzylthioinosine. 1997 May 1
19 7488121 Nucleoside triphosphate donors for nucleoside kinases: donor properties of UTP with human deoxycytidine kinase. 1995 Nov 2 1
20 7706474 Characterization of the deoxycytidine kinase promoter in human lymphoblast cell lines. 1995 Apr 1
21 7981228 Deoxycytidine kinase is phosphorylated in vitro by protein kinase C alpha. 1994 Nov 10 1
22 8095026 Effect of deoxycytidine on 2-chloro-deoxyadenosine-mediated growth inhibition of normal human erythroid and myeloid progenitor cells. 1993 Mar 2
23 8399394 Purification and characterization of deoxycytidine kinase from acute myeloid leukemia cell mitochondria. 1993 Oct 6 3
24 8422376 Binding of substrates to human deoxycytidine kinase studied with ligand-dependent quenching of enzyme intrinsic fluorescence. 1993 Jan 19 1
25 1406603 Nucleotide specificity of human deoxycytidine kinase. 1992 Sep 2
26 3019066 Pyrimidine salvage enzymes in human tonsil lymphocytes: II. Purification and properties of deoxycytidine kinase. 1985 1
27 51655 Deoxycytidine kinase: properties of the enzyme from human leukemic granulocytes. 1975 Nov 1
28 4762632 Phosphorylation of 5-halogenated deoxycytidine analogues by deoxycytidine kinase. 1973 Nov 1