Phenacetin

cytochrome P450, family 1, subfamily a, polypeptide 2 ; Rattus norvegicus







28 Article(s)
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1 34881402 In Vitro and In Vivo Assessment of Atemoya Fruit (Annona atemoya) for Food-Drug Interactions. 2022 Mar 3
2 28893642 Enzyme-inducing effects of berberine on cytochrome P450 1A2 in vitro and in vivo. 2017 Nov 15 2
3 26226765 [Effect of Fuzheng Huayu recipe on CYP450 isozymes in normal and liver fibrosis rats]. 2015 Mar 1
4 24587011 Inhibition of baicalin on metabolism of phenacetin, a probe of CYP1A2, in human liver microsomes and in rats. 2014 1
5 25464097 Evaluation of the effect of apatinib (YN968D1) on cytochrome P450 enzymes with cocktail probe drugs in rats by UPLC-MS/MS. 2014 Dec 15 1
6 23215698 Astragaloside IV inhibited the activity of CYP1A2 in liver microsomes and influenced theophylline pharmacokinetics in rats. 2013 Jan 1
7 23802435 Effects of repeated allopurinol administration on rat cytochrome P450 activity. 2013 May 1
8 23975028 Identification and characterization of psoralen and isopsoralen as potent CYP1A2 reversible and time-dependent inhibitors in human and rat preclinical studies. 2013 Nov 1
9 24076258 Pharmacokinetic changes of unbound theophylline are due to plasma protein binding displacement and CYP1A2 activity inhibition by baicalin in rats. 2013 Nov 25 1
10 21899995 Tanshinone I increases CYP1A2 protein expression and enzyme activity in primary rat hepatocytes. 2012 Jan 15 1
11 22341342 Phenacetin O-deethylation is a useful tool for evaluation of hepatic functional reserve in rats with CCl(4)-induced chronic liver injury. 2012 Jun 15 2
12 22693911 [Influence of jinlingzi powder with different compatibility on activity of cytochrome P1 A2 from rat liver microsomes]. 2012 Mar 1
13 23235327 Effects of schizonepetin on activity and mRNA expression of cytochrome p450 enzymes in rats. 2012 Dec 12 1
14 22007516 [Effects of Schisandra chinensis (Wuweizi) constituents on the activity of hepatic microsomal CYP450 isozymes in rats detected by using a cocktail probe substrates method]. 2011 Aug 1
15 19350452 Mechanism-based inhibition of CYP1A2 by antofloxacin, an 8-NH2 derivative of levofloxacin in rats. 2009 Apr 2
16 19403289 Effects of major tanshinones isolated from Danshen (Salvia miltiorrhiza) on rat CYP1A2 expression and metabolism of model CYP1A2 probe substrates. 2009 Aug 1
17 20027151 Evaluation of the activity of P450 enzymes in rats: use of the single marker or combined drug administration. 2009 1
18 17418998 Effect of berberine on hepatocyte proliferation, inducible nitric oxide synthase expression, cytochrome P450 2E1 and 1A2 activities in diethylnitrosamine- and phenobarbital-treated rats. 2008 Nov 1
19 17881659 Evaluation of the assumptions of an ontogeny model of rat hepatic cytochrome P450 activity. 2007 Dec 1
20 12586202 Identification of cytochrome P450 1A2 as enzyme involved in the microsomal metabolism of Huperzine A. 2003 Feb 14 1
21 11911841 Substrate specificity for rat cytochrome P450 (CYP) isoforms: screening with cDNA-expressed systems of the rat. 2002 Mar 1 1
22 12222751 Decreased hepatic drug metabolising enzyme activity in rats with nitrosamine-induced tumours. 2002 1
23 15618674 Identification of inhibitory component in cinnamon--O-methoxycinnamaldehyde inhibits CYP1A2 and CYP2E1-. 2002 2
24 8905919 Intermolecular interactions of antimicrobial fluoroquinolones with purified rat liver CYP1A2 studied by proton nuclear magnetic resonance spectroscopy. 1996 Oct 2
25 8373445 Methoxyresorufin and benzyloxyresorufin: substrates preferentially metabolized by cytochromes P4501A2 and 2B, respectively, in the rat and mouse. 1993 Sep 1 1
26 8461047 Metabolism of phenacetin in V79 Chinese hamster cell cultures expressing rat liver cytochrome P4501A2 compared to isolated rat hepatocytes. 1993 Mar 9 1
27 2773513 Selective destruction of cytochrome P-450d and associated monooxygenase activity by carbon tetrachloride in the rat. 1989 Jul 1
28 3099430 The 3-methylcholanthrene-mimetic effect of 4,4'-dichlorobiphenyl-treatment on phenacetin-induced hepatic glutathione depletion and liver microsomal phenacetin O-deethylation in rats. 1986 Dec 15 1