avasimibe

sterol O-acyltransferase 1 ; Homo sapiens







13 Article(s)
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PMID
Title
Pub. Year
#Total Relationships
1 34407453 Pharmacologic and genetic inhibition of cholesterol esterification enzymes reduces tumour burden: A systematic review and meta-analysis of preclinical models. 2022 Feb 1
2 34914638 Ceramide-mediated gut dysbiosis enhances cholesterol esterification and promotes colorectal tumorigenesis in mice. 2022 Feb 8 1
3 32451414 Avasimibe exerts anticancer effects on human glioblastoma cells via inducing cell apoptosis and cell cycle arrest. 2021 Jan 1
4 33637695 Cholesterol activates the Wnt/PCP-YAP signaling in SOAT1-targeted treatment of colon cancer. 2021 Feb 26 1
5 34052835 Simultaneously targeting SOAT1 and CPT1A ameliorates hepatocellular carcinoma by disrupting lipid homeostasis. 2021 May 29 1
6 34790132 SOAT1 Promotes Gastric Cancer Lymph Node Metastasis Through Lipid Synthesis. 2021 1
7 26982734 Potentiating the antitumour response of CD8(+) T cells by modulating cholesterol metabolism. 2016 Mar 31 1
8 19167888 Novel 1,4-diarylpiperidine-4-methylureas as anti-hyperlipidemic agents: dual effectors on acyl-CoA:cholesterol O-acyltransferase and low-density lipoprotein receptor expression. 2009 Feb 15 1
9 12595916 Pharmacology of the ACAT inhibitor avasimibe (CI-1011). 2003 Spring 3
10 11882316 Anti-atherogenic effects of the acyl-CoA:cholesterol acyltransferase inhibitor, avasimibe (CI-1011), in cultured primary human macrophages. 2002 Mar 2
11 12498009 Avasimibe Pfizer. 2002 Sep 3
12 10195921 ApoB100 secretion from HepG2 cells is decreased by the ACAT inhibitor CI-1011: an effect associated with enhanced intracellular degradation of ApoB. 1999 Apr 4
13 9568739 The ACAT inhibitor, CI-1011 is effective in the prevention and regression of aortic fatty streak area in hamsters. 1998 Mar 1