Phosphatidylcholines

phosphate cytidylyltransferase 1A, choline ; Homo sapiens







26 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 33521992 Methylome and transcriptome profiling revealed epigenetic silencing of LPCAT1 and PCYT1A associated with lipidome alterations in polycystic ovary syndrome. 2021 Sep 1
2 32186954 Differential dephosphorylation of CTP:phosphocholine cytidylyltransferase upon translocation to nuclear membranes and lipid droplets. 2020 May 1 4
3 32703435 PCYT1A suppresses proliferation and migration via inhibiting mTORC1 pathway in lung adenocarcinoma. 2020 Aug 20 1
4 30559292 Disease-linked mutations in the phosphatidylcholine regulatory enzyme CCTα impair enzymatic activity and fold stability. 2019 Feb 1 3
5 30629659 KDM2B regulates choline kinase expression and neuronal differentiation of neuroblastoma cells. 2019 2
6 30692541 Nuclear lipid droplets derive from a lipoprotein precursor and regulate phosphatidylcholine synthesis. 2019 Jan 28 2
7 31418690 Accelerated phosphatidylcholine turnover in macrophages promotes adipose tissue inflammation in obesity. 2019 Aug 16 1
8 29411327 Gene variants of the phosphatidylcholine synthesis pathway do not contribute to RDS in the Chinese population. 2018 Feb 1
9 29728535 How CCTα puts a leash on phospholipid synthesis. 2018 May 4 4
10 30115754 Phosphatidylcholine synthesis regulates triglyceride storage and chylomicron secretion by Caco2 cells. 2018 Oct 1
11 30148882 Phospholipid synthesis fueled by lipid droplets drives the structural development of poliovirus replication organelles. 2018 Aug 1
12 28686226 MYC is a positive regulator of choline metabolism and impedes mitophagy-dependent necroptosis in diffuse large B-cell lymphoma. 2017 Jul 7 1
13 26108622 Nuclear-localized CTP:phosphocholine cytidylyltransferase α regulates phosphatidylcholine synthesis required for lipid droplet biogenesis. 2015 Aug 15 7
14 24387990 Mutations in PCYT1A, encoding a key regulator of phosphatidylcholine metabolism, cause spondylometaphyseal dysplasia with cone-rod dystrophy. 2014 Jan 2 1
15 24440820 Choline kinase alpha expression during RA-induced neuronal differentiation: role of C/EBPβ. 2014 Apr 4 2
16 20096375 Specific interaction between E2F1 and Sp1 regulates the expression of murine CTP:phosphocholine cytidylyltransferase alpha during the S phase. 2010 Apr 2
17 18559668 Cytokine secretion requires phosphatidylcholine synthesis. 2008 Jun 16 1
18 18614529 15-deoxy-Delta12,14-prostaglandin J2 impairs phosphatidylcholine synthesis and induces nuclear accumulation of thiol-modified cytidylyltransferase. 2008 Sep 5 1
19 18930839 Novel function of the human presqualene diphosphate phosphatase as a type II phosphatidate phosphatase in phosphatidylcholine and triacylglyceride biosynthesis pathways. 2008 Nov-Dec 1
20 17804406 Calmodulin binds and stabilizes the regulatory enzyme, CTP: phosphocholine cytidylyltransferase. 2007 Nov 16 1
21 15788406 Oxysterols inhibit phosphatidylcholine synthesis via ERK docking and phosphorylation of CTP:phosphocholine cytidylyltransferase. 2005 Jun 3 2
22 15982005 CTP:phosphocholine cytidylyltransferase binds anionic phospholipid vesicles in a cross-bridging mode. 2005 Jul 5 2
23 15210848 Upregulation of surfactant synthesis triggers ABCA1-mediated basolateral phospholipid efflux. 2004 Sep 2
24 15569411 Effect of vasoactive intestinal peptide on pulmonary surfactants phospholipid synthesis in lung explants. 2004 Dec 1
25 12221122 The major sites of cellular phospholipid synthesis and molecular determinants of Fatty Acid and lipid head group specificity. 2002 Sep 2
26 9593753 Cloning and characterization of a second human CTP:phosphocholine cytidylyltransferase. 1998 May 29 1