pyrimidine

uridine monophosphate synthetase ; Homo sapiens







23 Article(s)
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1 35169125 UBE2T-mediated Akt ubiquitination and Akt/β-catenin activation promotes hepatocellular carcinoma development by increasing pyrimidine metabolism. 2022 Feb 15 1
2 35356460 Case Report: A Novel Missense Mutation c.517G>C in the UMPS Gene Associated With Mild Orotic Aciduria. 2022 2
3 32661439 Metabolic engineering generates a transgene-free safety switch for cell therapy. 2020 Dec 2
4 28847964 Global metabolic reprogramming of colorectal cancer occurs at adenoma stage and is induced by MYC. 2017 Sep 12 1
5 25112781 Impact of the expression of thymidylate synthase and dihydropyrimidine dehydrogenase genes on survival in stage II/III gastric cancer. 2015 Jul 2
6 26700594 Orotate phosphoribosyltransferase localizes to the Golgi complex and its expression levels affect the sensitivity to anti-cancer drug 5-fluorouracil. 2015 2
7 24507637 A unique insertion of low complexity amino acid sequence underlies protein-protein interaction in human malaria parasite orotate phosphoribosyltransferase and orotidine 5'-monophosphate decarboxylase. 2014 Mar 2
8 23585020 Metabolomics identifies pyrimidine starvation as the mechanism of 5-aminoimidazole-4-carboxamide-1-β-riboside-induced apoptosis in multiple myeloma cells. 2013 Jul 2
9 21367966 Identification of the UMP synthase gene by establishment of uracil auxotrophic mutants and the phenotypic complementation system in the marine diatom Phaeodactylum tricornutum. 2011 May 1
10 21401501 Neurological disorders of purine and pyrimidine metabolism. 2011 1
11 21631301 Frequency of uridine monophosphate synthase Gly(213)Ala polymorphism in Caucasian gastrointestinal cancer patients and healthy subjects, investigated by means of new, rapid genotyping assays. 2011 Oct 2
12 21791367 Thymidylate synthase, dihydropyrimidine dehydrogenase, thymidine phosphorylase, orotate phosphoribosyltransferase mRNA expression in lung cancer metastatic lymph node samples obtained by endobronchial ultrasound-guided transbronchial needle aspiration: a pilot study. 2011 Sep 2
13 19292447 Transition states of Plasmodium falciparum and human orotate phosphoribosyltransferases. 2009 Apr 8 1
14 17513443 Orotic acid excretion and arginine metabolism. 2007 Jun 1
15 15683248 A novel enzyme complex of orotate phosphoribosyltransferase and orotidine 5'-monophosphate decarboxylase in human malaria parasite Plasmodium falciparum: physical association, kinetics, and inhibition characterization. 2005 Feb 8 1
16 15060742 Gene expression of 5-fluorouracil metabolic enzymes in primary colorectal cancer and corresponding liver metastasis. 2004 May 1
17 15162399 Control of pyrimidine biosynthesis in "Pseudomonas alkanolytica" ATCC 21034. 2004 2
18 10891536 Different mechanisms of acquired resistance to fluorinated pyrimidines in human colorectal cancer cells. 2000 Aug 1
19 9042911 Molecular cloning of the human UMP synthase gene and characterization of point mutations in two hereditary orotic aciduria families. 1997 Mar 1
20 1500593 Relationship between genetic merit of Holstein bulls and deficiency of uridine-5'-monophosphate synthase. 1992 Jul 1
21 2502942 [Immune deficiencies secondary to enzymopathies]. 1989 Jun 1
22 2996510 Human spleen dihydroorotate dehydrogenase: a study of inhibition of the enzyme. 1985 Aug 1
23 5032526 Mechanism of allopurinol-mediated increase in enzyme activity in man. 1972 Jul 2