| 1 |
35034963 | Association of ITPA gene polymorphisms with adverse effects of AZA/6-MP administration: a systematic review and meta-analysis. | 2022 Feb |
2 |
| 2 |
35067667 | Inosine Triphosphate Pyrophosphatase and NUDT15 are Good Predictors of Clinical Outcomes in Thiopurine-Treated Chinese Patients with Inflammatory Bowel Disease. | 2022 Jun 1 |
1 |
| 3 |
35159194 | Inosine Triphosphate Pyrophosphatase (ITPase): Functions, Mutations, Polymorphisms and Its Impact on Cancer Therapies. | 2022 Jan 24 |
1 |
| 4 |
29327413 | ITPA Activity in Children Treated by Azathioprine: Relationship to the Occurrence of Adverse Drug Reactions and Inflammatory Response. | 2018 Jun |
4 |
| 5 |
30106365 | Neutropenia related to an azathioprine metabolic disorder induced by an inosine triphosphate pyrophosphohydrolase (ITPA) gene mutation in a patient with PR3-ANCA-positive microscopic polyangiitis
. | 2018 Nov |
4 |
| 6 |
28650902 | ITPA Activity in Adults and Children Treated With or Without Azathioprine: Relationship Between TPMT Activity, Thiopurine Metabolites, and Co-medications. | 2017 Oct |
6 |
| 7 |
26674571 | TPMT and ITPA genetic variants in Lithuanian inflammatory bowel disease patients: Prevalence and azathioprine-related side effects. | 2016 Mar |
5 |
| 8 |
27307154 | A Simple Method for TPMT and ITPA Genotyping Using Multiplex HRMA for Patients Treated with Thiopurine Drugs. | 2016 Oct |
2 |
| 9 |
23787247 | Deletion of glutathione-s-transferase m1 reduces azathioprine metabolite concentrations in young patients with inflammatory bowel disease. | 2014 Jan |
1 |
| 10 |
23770441 | Analysis of human ITPase nucleobase specificity by site-directed mutagenesis. | 2013 Sep |
1 |
| 11 |
22673202 | Determination of inosine triphosphate pyrophosphatase phenotype in human red blood cells using HPLC. | 2012 Aug |
1 |
| 12 |
21544018 | Association between adverse effects under azathioprine therapy and inosine triphosphate pyrophosphatase activity in patients with chronic inflammatory bowel disease. | 2011 Jun |
1 |
| 13 |
21961091 | A pharmacogenetics study of TPMT and ITPA genes detects a relationship with side effects and clinical response in patients with inflammatory bowel disease receiving Azathioprine. | 2011 Sep |
7 |
| 14 |
19682085 | Association between inosine triphosphate pyrophosphohydrolase deficiency and azathioprine-related adverse drug reactions in the Chinese kidney transplant recipients. | 2010 Jun |
4 |
| 15 |
19914375 | Quantitative in vitro and in vivo characterization of the human P32T mutant ITPase. | 2010 Feb |
1 |
| 16 |
20308917 | Influences of thiopurine methyltransferase genotype and activity on thiopurine-induced leukopenia in Korean patients with inflammatory bowel disease: a retrospective cohort study. | 2010 Nov-Dec |
1 |
| 17 |
20367526 | Inosine triphosphate pyrophosphatase 94C>A polymorphism: clinical implications for patients with systemic lupus erythematosus treated with azathioprine. | 2010 May |
5 |
| 18 |
19129747 | Pro32Thr polymorphism of inosine triphosphate pyrophosphatase gene predicts efficacy of low-dose azathioprine for patients with systemic lupus erythematosus. | 2009 May |
5 |
| 19 |
19214663 | Thiopurine S-methyltransferase and inosine triphosphate pyrophosphohydrolase genes in Japanese patients with inflammatory bowel disease in whom adverse drug reactions were induced by azathioprine/6-mercaptopurine treatment. | 2009 |
8 |
| 20 |
19229528 | TPMT but not ITPA gene polymorphism influences the risk of azathioprine intolerance in renal transplant recipients. | 2009 May |
2 |
| 21 |
18090994 | Thiopurine-methyltransferase and inosine triphosphate pyrophosphatase polymorphism in a liver transplant recipient developing nodular regenerative hyperplasia on low-dose azathioprine. | 2008 Jan |
1 |
| 22 |
17113761 | The ITPA c.94C>A and g.IVS2+21A>C sequence variants contribute to missplicing of the ITPA gene. | 2007 Jan |
1 |
| 23 |
17304144 | Analysis of ITPA phenotype-genotype correlation in the Bulgarian population revealed a novel gene variant in exon 6. | 2007 Feb |
2 |
| 24 |
17924837 | Pharmacogenetic significance of inosine triphosphatase. | 2007 Sep |
1 |
| 25 |
16431304 | Inosine triphosphate pyrophosphatase and thiopurine s-methyltransferase genotypes relationship to azathioprine-induced myelosuppression. | 2006 Jan |
5 |
| 26 |
16611274 | Pharmacogenetics of thiopurine therapy in paediatric IBD patients. | 2006 Apr 15 |
2 |
| 27 |
29783434 | Typing TPMT and ITPase to detect azathioprine toxicity. | 2006 Feb |
1 |
| 28 |
16214825 | Association of inosine triphosphatase 94C>A and thiopurine S-methyltransferase deficiency with adverse events and study drop-outs under azathioprine therapy in a prospective Crohn disease study. | 2005 Dec |
5 |
| 29 |
15167706 | Adverse drug reactions to azathioprine therapy are associated with polymorphism in the gene encoding inosine triphosphate pyrophosphatase (ITPase). | 2004 Mar |
4 |
| 30 |
15322947 | Distribution of ITPA P32T alleles in multiple world populations. | 2004 |
1 |
| 31 |
15564886 | Lack of association between the ITPA 94C>A polymorphism and adverse effects from azathioprine. | 2004 Nov |
1 |
| 32 |
15571265 | Mutation in the ITPA gene predicts intolerance to azathioprine. | 2004 Oct |
3 |
| 33 |
15571266 | Allele frequency of inosine triphosphate pyrophosphatase gene polymorphisms in a Japanese population. | 2004 Oct |
1 |