| 1 |
35109648 | Oxidation Enhances Binding of Extrahelical 5-Methyl-Cytosines by Thymine DNA Glycosylase. | 2022 Feb 17 |
1 |
| 2 |
35159032 | The Role of Thymine DNA Glycosylase in Transcription, Active DNA Demethylation, and Cancer. | 2022 Feb 1 |
2 |
| 3 |
33561435 | TET-TDG Active DNA Demethylation at CpG and Non-CpG Sites. | 2021 Apr 16 |
6 |
| 4 |
34567494 | Direct decarboxylation of ten-eleven translocation-produced 5-carboxylcytosine in mammalian genomes forms a new mechanism for active DNA demethylation. | 2021 Sep 1 |
1 |
| 5 |
34641273 | Interaction of Thymine DNA Glycosylase with Oxidised 5-Methyl-cytosines in Their Amino- and Imino-Forms. | 2021 Sep 22 |
1 |
| 6 |
32728616 | Insulin and Metformin Control Cell Proliferation by Regulating TDG-Mediated DNA Demethylation in Liver and Breast Cancer Cells. | 2020 Sep 25 |
1 |
| 7 |
31693361 | Excision of 5-Carboxylcytosine by Thymine DNA Glycosylase. | 2019 Nov 27 |
2 |
| 8 |
29660017 | Defining the impact of sumoylation on substrate binding and catalysis by thymine DNA glycosylase. | 2018 Jun 1 |
6 |
| 9 |
28555658 | TET-mediated active DNA demethylation: mechanism, function and beyond. | 2017 Sep |
6 |
| 10 |
28973458 | TET2- and TDG-mediated changes are required for the acquisition of distinct histone modifications in divergent terminal differentiation of myeloid cells. | 2017 Sep 29 |
2 |
| 11 |
26620559 | Uracil-DNA Glycosylase UNG Promotes Tet-mediated DNA Demethylation. | 2016 Jan 8 |
4 |
| 12 |
26932196 | Biochemical reconstitution of TET1-TDG-BER-dependent active DNA demethylation reveals a highly coordinated mechanism. | 2016 Mar 2 |
6 |
| 13 |
27580719 | Structural basis of damage recognition by thymine DNA glycosylase: Key roles for N-terminal residues. | 2016 Dec 1 |
3 |
| 14 |
27587280 | Analysis of the machinery and intermediates of the 5hmC-mediated DNA demethylation pathway in aging on samples from the MARK-AGE Study. | 2016 Aug 29 |
2 |
| 15 |
27805810 | Structural Basis for Excision of 5-Formylcytosine by Thymine DNA Glycosylase. | 2016 Nov 15 |
1 |
| 16 |
25632825 | Differential stabilities and sequence-dependent base pair opening dynamics of Watson-Crick base pairs with 5-hydroxymethylcytosine, 5-formylcytosine, or 5-carboxylcytosine. | 2015 Feb 10 |
2 |
| 17 |
26358812 | Thymine DNA glycosylase exhibits negligible affinity for nucleobases that it removes from DNA. | 2015 Oct 30 |
3 |
| 18 |
23195996 | MBD4 and TDG: multifaceted DNA glycosylases with ever expanding biological roles. | 2013 Mar-Apr |
2 |
| 19 |
23602152 | Genome-wide analysis reveals TET- and TDG-dependent 5-methylcytosine oxidation dynamics. | 2013 Apr 25 |
1 |
| 20 |
23602153 | Genome-wide profiling of 5-formylcytosine reveals its roles in epigenetic priming. | 2013 Apr 25 |
1 |
| 21 |
23952905 | Histone deacetylase SIRT1 modulates and deacetylates DNA base excision repair enzyme thymine DNA glycosylase. | 2013 Nov 15 |
1 |
| 22 |
24063363 | Divergent mechanisms for enzymatic excision of 5-formylcytosine and 5-carboxylcytosine from DNA. | 2013 Oct 23 |
1 |
| 23 |
22327402 | Thymine DNA glycosylase specifically recognizes 5-carboxylcytosine-modified DNA. | 2012 Feb 12 |
1 |
| 24 |
22573813 | Lesion processing by a repair enzyme is severely curtailed by residues needed to prevent aberrant activity on undamaged DNA. | 2012 May 22 |
3 |
| 25 |
22608206 | Unique mutational profile associated with a loss of TDG expression in the rectal cancer of a patient with a constitutional PMS2 deficiency. | 2012 Jul 1 |
1 |
| 26 |
22711938 | Synthesis of DNA oligos containing 2'-deoxy-2'-fluoro-D-arabinofuranosyl-5-carboxylcytosine as hTDG inhibitor. | 2012 Jul 1 |
4 |
| 27 |
22910204 | Enzymatic analysis of Tet proteins: key enzymes in the metabolism of DNA methylation. | 2012 |
2 |
| 28 |
22962365 | Excision of 5-hydroxymethyluracil and 5-carboxylcytosine by the thymine DNA glycosylase domain: its structural basis and implications for active DNA demethylation. | 2012 Nov 1 |
1 |
| 29 |
21722948 | Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair. | 2011 Jul 8 |
2 |
| 30 |
21817016 | Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA. | 2011 Sep 2 |
1 |
| 31 |
21862836 | Thymine DNA glycosylase can rapidly excise 5-formylcytosine and 5-carboxylcytosine: potential implications for active demethylation of CpG sites. | 2011 Oct 14 |
8 |
| 32 |
19659441 | Active DNA demethylation mediated by DNA glycosylases. | 2009 |
1 |
| 33 |
19880517 | Role of two strictly conserved residues in nucleotide flipping and N-glycosylic bond cleavage by human thymine DNA glycosylase. | 2009 Dec 25 |
2 |
| 34 |
12493755 | The main role of human thymine-DNA glycosylase is removal of thymine produced by deamination of 5-methylcytosine and not removal of ethenocytosine. | 2003 Mar 7 |
3 |
| 35 |
12505994 | Xeroderma pigmentosum group C protein interacts physically and functionally with thymine DNA glycosylase. | 2003 Jan 2 |
2 |
| 36 |
12711670 | The versatile thymine DNA-glycosylase: a comparative characterization of the human, Drosophila and fission yeast orthologs. | 2003 May 1 |
2 |
| 37 |
12954776 | Human thymine DNA glycosylase (TDG) and methyl-CpG-binding protein 4 (MBD4) excise thymine glycol (Tg) from a Tg:G mispair. | 2003 Sep 15 |
2 |
| 38 |
10767625 | Thymine-DNA glycosylase and G to A transition mutations at CpG sites. | 2000 Apr |
1 |
| 39 |
10938281 | Separating substrate recognition from base hydrolysis in human thymine DNA glycosylase by mutational analysis. | 2000 Oct 27 |
2 |
| 40 |
9794235 | Expression of T:G mismatch-specific thymidine-DNA glycosylase and DNA methyl transferase genes during development and tumorigenesis. | 1998 Sep 24 |
2 |
| 41 |
9299239 | Chromosomal localizations and molecular analysis of TDG gene-related sequences. | 1997 Sep 1 |
1 |