Thymine

thymine DNA glycosylase ; Homo sapiens







42 Article(s)
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Pub. Year
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1 33561435 TET-TDG Active DNA Demethylation at CpG and Non-CpG Sites. 2021 Apr 16 1
2 34641273 Interaction of Thymine DNA Glycosylase with Oxidised 5-Methyl-cytosines in Their Amino- and Imino-Forms. 2021 Sep 22 1
3 31639437 Additional functions of selected proteins involved in DNA repair. 2020 Jan 1
4 30841696 Defining the Role of Nucleotide Flipping in Enzyme Specificity Using 19F NMR. 2019 Mar 27 4
5 31239841 TDG Gene Polymorphisms and Their Possible Association with Colorectal Cancer: A Case Control Study. 2019 2
6 29253232 Dynamics of the excised base release in thymine DNA glycosylase during DNA repair process. 2018 Jan 25 1
7 29660017 Defining the impact of sumoylation on substrate binding and catalysis by thymine DNA glycosylase. 2018 Jun 1 2
8 27890638 Aberrant base excision repair pathway of oxidatively damaged DNA: Implications for degenerative diseases. 2017 Jun 5
9 29098062 Mutation Spectrum Induced by 8-Bromoguanine, a Base Damaged by Reactive Brominating Species, in Human Cells. 2017 1
10 24692658 Aberrant repair initiated by mismatch-specific thymine-DNA glycosylases provides a mechanism for the mutational bias observed in CpG islands. 2014 Jun 1
11 25151120 Human DNA glycosylase enzyme TDG repairs thymine mispaired with exocyclic etheno-DNA adducts. 2014 Nov 1
12 25375110 A germline polymorphism of thymine DNA glycosylase induces genomic instability and cellular transformation. 2014 Nov 1
13 27493500 Structural and mutation studies of two DNA demethylation related glycosylases: MBD4 and TDG. 2014 1
14 23195996 MBD4 and TDG: multifaceted DNA glycosylases with ever expanding biological roles. 2013 Mar-Apr 2
15 23337108 Selective excision of 5-carboxylcytosine by a thymine DNA glycosylase mutant. 2013 Mar 25 1
16 23952905 Histone deacetylase SIRT1 modulates and deacetylates DNA base excision repair enzyme thymine DNA glycosylase. 2013 Nov 15 1
17 22573813 Lesion processing by a repair enzyme is severely curtailed by residues needed to prevent aberrant activity on undamaged DNA. 2012 May 22 1
18 22706113 [Oxidation and deamination of nucleobases as an epigenetic tool]. 2012 May 24 1
19 22809372 A density functional theory study on the kinetics and thermodynamics of N-glycosidic bond cleavage in 5-substituted 2'-deoxycytidines. 2012 Aug 14 1
20 22962365 Excision of 5-hydroxymethyluracil and 5-carboxylcytosine by the thymine DNA glycosylase domain: its structural basis and implications for active DNA demethylation. 2012 Nov 1 1
21 23165212 Transcriptional regulation of thymine DNA glycosylase (TDG) by the tumor suppressor protein p53. 2012 Dec 15 2
22 21097883 Stoichiometry and affinity for thymine DNA glycosylase binding to specific and nonspecific DNA. 2011 Mar 2
23 21474392 Dependence of substrate binding and catalysis on pH, ionic strength, and temperature for thymine DNA glycosylase: Insights into recognition and processing of G·T mispairs. 2011 May 5 2
24 21722948 Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair. 2011 Jul 8 2
25 19966277 Opposing regulatory roles of phosphorylation and acetylation in DNA mispair processing by thymine DNA glycosylase. 2010 Mar 2
26 19880517 Role of two strictly conserved residues in nucleotide flipping and N-glycosylic bond cleavage by human thymine DNA glycosylase. 2009 Dec 25 2
27 18452947 Characterization of Dnmt3b:thymine-DNA glycosylase interaction and stimulation of thymine glycosylase-mediated repair by DNA methyltransferase(s) and RNA. 2008 Jun 6 1
28 17116428 The enigmatic thymine DNA glycosylase. 2007 Apr 1 1
29 17602166 Excision of 5-halogenated uracils by human thymine DNA glycosylase. Robust activity for DNA contexts other than CpG. 2007 Sep 21 2
30 16984202 Specificity of human thymine DNA glycosylase depends on N-glycosidic bond stability. 2006 Sep 27 1
31 12493755 The main role of human thymine-DNA glycosylase is removal of thymine produced by deamination of 5-methylcytosine and not removal of ethenocytosine. 2003 Mar 7 3
32 12711670 The versatile thymine DNA-glycosylase: a comparative characterization of the human, Drosophila and fission yeast orthologs. 2003 May 1 1
33 12954776 Human thymine DNA glycosylase (TDG) and methyl-CpG-binding protein 4 (MBD4) excise thymine glycol (Tg) from a Tg:G mispair. 2003 Sep 15 2
34 11864601 Association of CBP/p300 acetylase and thymine DNA glycosylase links DNA repair and transcription. 2002 Feb 2
35 12119040 Substrate specificity and sequence preference of G:T mismatch repair: incision at G:T, O6-methylguanine:T, and G:U mispairs in DNA by human cell extracts. 2002 Jul 23 1
36 11506820 The HAP1 protein stimulates the turnover of human mismatch-specific thymine-DNA-glycosylase to process 3,N(4)-ethenocytosine residues. 2001 Sep 1 1
37 11554300 Thymine DNA glycosylase. 2001 1
38 10767625 Thymine-DNA glycosylase and G to A transition mutations at CpG sites. 2000 Apr 1
39 10938281 Separating substrate recognition from base hydrolysis in human thymine DNA glycosylase by mutational analysis. 2000 Oct 27 1
40 9867812 Human thymine DNA glycosylase binds to apurinic sites in DNA but is displaced by human apurinic endonuclease 1. 1999 Jan 1 1
41 9685338 Kinetics of the action of thymine DNA glycosylase. 1998 Aug 7 3
42 9144158 Investigation of the mechanisms of DNA binding of the human G/T glycosylase using designed inhibitors. 1997 May 13 1