Calcitriol

cytochrome P450, family 24, subfamily a, polypeptide 1 ; Rattus norvegicus







28 Article(s)
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1 33596463 Altered expression of the vitamin D metabolizing enzymes CYP27B1 and CYP24A1 under the context of prostate aging and pathologies. 2021 May 1
2 31289106 Specificity of the Redox Complex between Cytochrome P450 24A1 and Adrenodoxin Relies on Carbon-25 Hydroxylation of Vitamin-D Substrate. 2019 Sep 2
3 27173620 Expression pattern of CYP24 in liver during ageing in long-term diabetes. 2016 Jun 1
4 25425001 The vitamin D receptor in the proximal renal tubule is a key regulator of serum 1α,25-dihydroxyvitamin D₃. 2015 Feb 1 1
5 25614971 High glucose upregulates CYP24A1 expression which attenuates the ability of 1,25(OH)2D3 to increase NGF secretion in a rat Schwann cell line RSC96. 2015 Mar 15 4
6 24202304 Role of local versus systemic vitamin D receptors in vascular calcification. 2014 Jan 1
7 20967888 Comparative effects of doxercalciferol (1α-hydroxyvitamin D₂) versus calcitriol (1α,25-dihydroxyvitamin D₃) on the expression of transporters and enzymes in the rat in vivo. 2011 Apr 1
8 21338573 A new insight into the role of rat cytochrome P450 24A1 in metabolism of selective analogs of 1α,25-dihydroxyvitamin D₃. 2011 May 1 3
9 21424825 Differential effects of vitamin d receptor agonists on gene expression in neonatal rat cardiomyocytes. 2011 Jun 1
10 19961857 Crystal structure of CYP24A1, a mitochondrial cytochrome P450 involved in vitamin D metabolism. 2010 Feb 19 2
11 16816472 [Recent studies on vitamin D metabolizing enzymes]. 2006 Jul 1
12 15574355 Metabolism of vitamin D3 by cytochromes P450. 2005 Jan 1 1
13 15836435 Molecular action of 1,25-dihydroxyvitamin D3 and phorbol ester on the activation of the rat cytochrome P450C24 (CYP24) promoter: role of MAP kinase activities and identification of an important transcription factor binding site. 2005 Aug 1 2
14 15877868 Age-related alteration of vitamin D metabolism in response to low-phosphate diet in rats. 2005 Mar 1
15 12048211 Role of MAP kinases in the 1,25-dihydroxyvitamin D3-induced transactivation of the rat cytochrome P450C24 (CYP24) promoter. Specific functions for ERK1/ERK2 and ERK5. 2002 Aug 16 4
16 12903199 Extensive methylation of CpG island of CYP24 gene in osteoblastic ROS17/2.8 cells. 2002 1
17 11149490 Newly established assay method for 25-hydroxyvitamin D3 24-hydroxylase revealed much lower Km for 25-hydroxyvitamin D3 than for 1alpha,25-dihydroxyvitamin D3. 2001 Jan 1
18 10231362 Metabolic studies using recombinant escherichia coli cells producing rat mitochondrial CYP24 CYP24 can convert 1alpha,25-dihydroxyvitamin D3 to calcitroic acid. 1999 May 7
19 9622848 Rat CYP24 catalyses 23S-hydroxylation of 26,26,26,27,27,27-hexafluorocalcitriol in vitro. 1998 May 1
20 9681485 Induction of the vitamin D 24-hydroxylase (CYP24) by 1,25-dihydroxyvitamin D3 is regulated by parathyroid hormone in UMR106 osteoblastic cells. 1998 Aug 1
21 9162038 1alpha,25-dihydroxyvitamin D3-24-hydroxylase (CYP24) hydroxylates the carbon at the end of the side chain (C-26) of the C-24-fluorinated analog of 1alpha,25-dihydroxyvitamin D3. 1997 May 30 1
22 8804428 Insulin markedly potentiates the capacity of parathyroid hormone to increase expression of 25-hydroxyvitamin D3-24-hydroxylase in rat osteoblastic cells in the presence of 1,25-dihydroxyvitamin D3. 1996 Sep 9 1
23 8939905 Transcriptional synergism between vitamin D-responsive elements in the rat 25-hydroxyvitamin D3 24-hydroxylase (CYP24) promoter. 1996 Nov 22 1
24 7649106 Variable in vivo regulation of rat vitamin D-dependent genes (osteopontin, Ca,Mg-adenosine triphosphatase, and 25-hydroxyvitamin D3 24-hydroxylase): implications for differing mechanisms of regulation and involvement of multiple factors. 1995 Sep 1
25 7786039 The role of dietary calcium in the physiology of vitamin D toxicity: excess dietary vitamin D3 blunts parathyroid hormone induction of kidney 1-hydroxylase. 1995 Jun 1 1
26 7835303 Regulation of 1,25-dihydroxyvitamin D3 receptors by parathyroid hormone in osteoblastic cells: role of second messenger pathways. 1995 Feb 1
27 7681765 Effects of 1,25-dihydroxyvitamin D3 and phorbol ester on 25-hydroxyvitamin D3 24-hydroxylase cytochrome P450 messenger ribonucleic acid levels in primary cultures of rat renal cells. 1993 Apr 1
28 8410379 Increase of renal 25-hydroxyvitamin D3-24-hydroxylase activity and its messenger ribonucleic acid level in 1 alpha-hydroxyvitamin D3-administered rats: possibility of the presence of two forms of 24-hydroxylase. 1993 Apr 1