Vitamin D

cytochrome P450, family 24, subfamily a, polypeptide 1 ; Rattus norvegicus







42 Article(s)
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1 33596463 Altered expression of the vitamin D metabolizing enzymes CYP27B1 and CYP24A1 under the context of prostate aging and pathologies. 2021 May 1
2 33865853 Elucidation of metabolic pathways of 25-hydroxyvitamin D3 mediated by CYP24A1 and CYP3A using Cyp24a1 knockout rats generated by CRISPR/Cas9 system. 2021 Jan-Jun 1
3 34769269 Development of In Vitro and In Vivo Evaluation Systems for Vitamin D Derivatives and Their Application to Drug Discovery. 2021 Oct 31 2
4 32001956 Association of increased renal Cyp24a1 gene expression with low plasma 1,25-dihydroxyvitamin D levels in rats with streptozotocin-induced diabetes. 2020 Jan 2
5 31289106 Specificity of the Redox Complex between Cytochrome P450 24A1 and Adrenodoxin Relies on Carbon-25 Hydroxylation of Vitamin-D Substrate. 2019 Sep 9
6 31805709 Combined Treatment with Omega-3 Fatty Acid and Cholecalciferol Increases 1,25-Dihydroxyvitamin D Levels by Modulating Dysregulation of Vitamin D Metabolism in 5/6 Nephrectomy Rats. 2019 Dec 1 2
7 27173620 Expression pattern of CYP24 in liver during ageing in long-term diabetes. 2016 Jun 1
8 27574921 Calcitroic Acid-A Review. 2016 Oct 21 1
9 24326417 Characterization of an animal model of pregnancy-induced vitamin D deficiency due to metabolic gene dysregulation. 2014 Feb 2
10 23250517 Vitamin D inquiry in hippocampal neurons: consequences of vitamin D-VDR pathway disruption on calcium channel and the vitamin D requirement. 2013 Aug 3
11 23752060 Beta amyloid suppresses the expression of the vitamin d receptor gene and induces the expression of the vitamin d catabolic enzyme gene in hippocampal neurons. 2013 1
12 23872713 Pan-FGFR inhibition leads to blockade of FGF23 signaling, soft tissue mineralization, and cardiovascular dysfunction. 2013 Oct 1
13 22100522 25-Hydroxyvitamin D-24-hydroxylase (CYP24A1): its important role in the degradation of vitamin D. 2012 Jul 1 2
14 20969950 Vitamin D receptor and enzyme expression in dorsal root ganglia of adult female rats: modulation by ovarian hormones. 2011 Jan 1
15 19961857 Crystal structure of CYP24A1, a mitochondrial cytochrome P450 involved in vitamin D metabolism. 2010 Feb 19 4
16 20347976 Vitamin D analogues targeting CYP24 in chronic kidney disease. 2010 Jul 9
17 20450955 Systematic characterisation of the rat and human CYP24A1 promoter. 2010 Aug 30 2
18 20531451 Dysregulation of renal vitamin D metabolism in the uremic rat. 2010 Sep 2
19 17207766 Hybrid homology modeling and mutational analysis of cytochrome P450C24A1 (CYP24A1) of the Vitamin D pathway: insights into substrate specificity and membrane bound structure-function. 2007 Apr 15 4
20 17267207 25-Hydroxyvitamin D requirement for maintaining skeletal health utilising a Sprague-Dawley rat model. 2007 Mar 2
21 16502312 Effects of depleted uranium after short-term exposure on vitamin D metabolism in rat. 2006 Aug 1
22 15781002 Modulation of CYP27B1 and CYP24 mRNA expression in bone is independent of circulating 1,25(OH)2D3 levels. 2005 Apr 1
23 15836435 Molecular action of 1,25-dihydroxyvitamin D3 and phorbol ester on the activation of the rat cytochrome P450C24 (CYP24) promoter: role of MAP kinase activities and identification of an important transcription factor binding site. 2005 Aug 1 2
24 15111121 Rat cytochrome P450C24 (CYP24A1) and the role of F249 in substrate binding and catalytic activity. 2004 May 15 1
25 15225765 Affinity labeling of rat cytochrome P450C24 (CYP24) and identification of Ser57 as an active site residue. 2004 May 1
26 12520537 Expression, structure-function, and molecular modeling of vitamin D P450s. 2003 Feb 1 1
27 12054486 Regulation of renal vitamin D receptor is an important determinant of 1alpha,25-dihydroxyvitamin D(3) levels in vivo. 2002 May 1 2
28 12372434 Characterization of transgenic rats constitutively expressing vitamin D-24-hydroxylase gene. 2002 Oct 11 3
29 12498308 Development of a vitamin D-responsive organ culture system for adult and old rat intestine. 2002 Dec 1
30 10609555 Evidence for the impairment of the vitamin D activation pathway by cyclosporine A. 2000 Feb 1 1
31 10617584 Regulation of rat cytochrome P450C24 (CYP24) gene expression. Evidence for functional cooperation of Ras-activated Ets transcription factors with the vitamin D receptor in 1,25-dihydroxyvitamin D(3)-mediated induction. 2000 Jan 7 1
32 10441383 Physiological significance of C-28 hydroxylation in the metabolism of 1alpha,25-dihydroxyvitamin D(2). 1999 Aug 15 1
33 9143355 Salt concentration determines 1,25-dihydroxyvitamin D3 dependency of vitamin D receptor-retinoid X receptor--vitamin D-responsive element complex formation. 1997 May 1 1
34 8760262 Expression of the renal 25-hydroxyvitamin D-24-hydroxylase gene: regulation by dietary phosphate. 1996 Jul 1
35 8939905 Transcriptional synergism between vitamin D-responsive elements in the rat 25-hydroxyvitamin D3 24-hydroxylase (CYP24) promoter. 1996 Nov 22 3
36 8940000 Functional assessment of two vitamin D-responsive elements in the rat 25-hydroxyvitamin D3 24-hydroxylase gene. 1996 Nov 29 1
37 8144641 Identification of a vitamin D-responsive element in the 5'-flanking region of the rat 25-hydroxyvitamin D3 24-hydroxylase gene. 1994 Apr 8 2
38 8302863 Identification of a vitamin D-response element in the rat calcidiol (25-hydroxyvitamin D3) 24-hydroxylase gene. 1994 Feb 1 1
39 7681765 Effects of 1,25-dihydroxyvitamin D3 and phorbol ester on 25-hydroxyvitamin D3 24-hydroxylase cytochrome P450 messenger ribonucleic acid levels in primary cultures of rat renal cells. 1993 Apr 1
40 8410379 Increase of renal 25-hydroxyvitamin D3-24-hydroxylase activity and its messenger ribonucleic acid level in 1 alpha-hydroxyvitamin D3-administered rats: possibility of the presence of two forms of 24-hydroxylase. 1993 Apr 2
41 22217851 Characterization and regulation of the vitamin D hydroxylases. 1992 Dec 1
42 6332645 Identification of 24,25,26,27-tetranor-23-hydroxyvitamin D3 as a product of the renal metabolism of 24,25-dihydroxyvitamin D3. 1984 Jul 31 2