25 Article(s)Download |
PMID | Title | Pub. Year | #Total Relationships |
1 | 33421954 | Discovery of Thai mangrove tetranortriterpenoids as agonists of human pregnane-X-receptor and inhibitors against human carboxylesterase 2. | 2021 Feb | 1 |
2 | 32115554 | [Evaluation of the Oral Absorption of Ester-type Prodrugs]. | 2020 | 1 |
3 | 32123952 | Construction and application of a high-content analysis for identifying human carboxylesterase 2 inhibitors in living cell system. | 2020 Apr | 2 |
4 | 30867471 | Prognostic Impact of Carboxylesterase 2 in Cholangiocarcinoma. | 2019 Mar 13 | 1 |
5 | 31260759 | Discovery of a highly specific and efficacious inhibitor of human carboxylesterase 2 by large-scale screening. | 2019 Sep 15 | 1 |
6 | 31323527 | Synthesis, molecular docking, and biological evaluation of 3-oxo-2-tolylhydrazinylidene-4,4,4-trifluorobutanoates bearing higher and natural alcohol moieties as new selective carboxylesterase inhibitors. | 2019 Oct | 3 |
7 | 29421708 | Characterization and structure-activity relationship studies of flavonoids as inhibitors against human carboxylesterase 2. | 2018 Apr | 1 |
8 | 29709907 | Development of a Caco-2 Cell Line Carrying the Human Intestine-Type CES Expression Profile as a Promising Tool for Ester-Containing Drug Permeability Studies. | 2018 | 3 |
9 | 26750665 | Gambogic acid potentiates clopidogrel-induced apoptosis and attenuates irinotecan-induced apoptosis through down-regulating human carboxylesterase 1 and -2. | 2016 Sep | 1 |
10 | 26825642 | Age-Dependent Human Hepatic Carboxylesterase 1 (CES1) and Carboxylesterase 2 (CES2) Postnatal Ontogeny. | 2016 Jul | 1 |
11 | 26900660 | Design, synthesis, and structure-activity relationship study of glycyrrhetinic acid derivatives as potent and selective inhibitors against human carboxylesterase 2. | 2016 Apr 13 | 1 |
12 | 27149931 | Tissue-infiltrating plasma cells are an important source of carboxylesterase 2 contributing to the therapeutic efficacy of prodrugs. | 2016 Aug 1 | 2 |
13 | 24141856 | In vitro drug metabolism by human carboxylesterase 1: focus on angiotensin-converting enzyme inhibitors. | 2014 Jan | 1 |
14 | 24461291 | Undesired versus designed enzymatic cleavage of linkers for liver targeting. | 2014 Feb 15 | 1 |
15 | 24988246 | The pharmacogenetics of carboxylesterases: CES1 and CES2 genetic variants and their clinical effect. | 2014 | 2 |
16 | 25303639 | Design of enzymatically cleavable prodrugs of a potent platinum-containing anticancer agent. | 2014 Dec 1 | 2 |
17 | 21237253 | Lipopolysaccharide down-regulates carbolesterases 1 and 2 and reduces hydrolysis activity in vitro and in vivo via p38MAPK-NF-κB pathway. | 2011 Mar 25 | 1 |
18 | 20623318 | Homology modeling and metabolism prediction of human carboxylesterase-2 using docking analyses by GriDock: a parallelized tool based on AutoDock 4.0. | 2010 Sep | 1 |
19 | 17537833 | Interleukin-6 alters the cellular responsiveness to clopidogrel, irinotecan, and oseltamivir by suppressing the expression of carboxylesterases HCE1 and HCE2. | 2007 Sep | 1 |
20 | 17640957 | Haplotypes and a novel defective allele of CES2 found in a Japanese population. | 2007 Oct | 2 |
21 | 16011259 | [Stereoselectivity of skin carboxylesterase metabolism]. | 2005 Apr | 1 |
22 | 12607608 | Comprehensive evaluation of carboxylesterase-2 expression in normal human tissues using tissue array analysis. | 2002 Dec | 1 |
23 | 9169443 | Purification and cloning of a broad substrate specificity human liver carboxylesterase that catalyzes the hydrolysis of cocaine and heroin. | 1997 Jun 6 | 1 |
24 | 9300133 | Hydrolytic profile for ester- or amide-linkage by carboxylesterases pI 5.3 and 4.5 from human liver. | 1997 Aug | 1 |
25 | 8930175 | Metabolism of cocaine and heroin is catalyzed by the same human liver carboxylesterases. | 1996 Nov | 1 |