| 1 |
33421954 | Discovery of Thai mangrove tetranortriterpenoids as agonists of human pregnane-X-receptor and inhibitors against human carboxylesterase 2. | 2021 Feb |
1 |
| 2 |
32115554 | [Evaluation of the Oral Absorption of Ester-type Prodrugs]. | 2020 |
1 |
| 3 |
32123952 | Construction and application of a high-content analysis for identifying human carboxylesterase 2 inhibitors in living cell system. | 2020 Apr |
2 |
| 4 |
30867471 | Prognostic Impact of Carboxylesterase 2 in Cholangiocarcinoma. | 2019 Mar 13 |
1 |
| 5 |
31260759 | Discovery of a highly specific and efficacious inhibitor of human carboxylesterase 2 by large-scale screening. | 2019 Sep 15 |
1 |
| 6 |
31323527 | Synthesis, molecular docking, and biological evaluation of 3-oxo-2-tolylhydrazinylidene-4,4,4-trifluorobutanoates bearing higher and natural alcohol moieties as new selective carboxylesterase inhibitors. | 2019 Oct |
3 |
| 7 |
29421708 | Characterization and structure-activity relationship studies of flavonoids as inhibitors against human carboxylesterase 2. | 2018 Apr |
1 |
| 8 |
29709907 | Development of a Caco-2 Cell Line Carrying the Human Intestine-Type CES Expression Profile as a Promising Tool for Ester-Containing Drug Permeability Studies. | 2018 |
3 |
| 9 |
26750665 | Gambogic acid potentiates clopidogrel-induced apoptosis and attenuates irinotecan-induced apoptosis through down-regulating human carboxylesterase 1 and -2. | 2016 Sep |
1 |
| 10 |
26825642 | Age-Dependent Human Hepatic Carboxylesterase 1 (CES1) and Carboxylesterase 2 (CES2) Postnatal Ontogeny. | 2016 Jul |
1 |
| 11 |
26900660 | Design, synthesis, and structure-activity relationship study of glycyrrhetinic acid derivatives as potent and selective inhibitors against human carboxylesterase 2. | 2016 Apr 13 |
1 |
| 12 |
27149931 | Tissue-infiltrating plasma cells are an important source of carboxylesterase 2 contributing to the therapeutic efficacy of prodrugs. | 2016 Aug 1 |
2 |
| 13 |
24141856 | In vitro drug metabolism by human carboxylesterase 1: focus on angiotensin-converting enzyme inhibitors. | 2014 Jan |
1 |
| 14 |
24461291 | Undesired versus designed enzymatic cleavage of linkers for liver targeting. | 2014 Feb 15 |
1 |
| 15 |
24988246 | The pharmacogenetics of carboxylesterases: CES1 and CES2 genetic variants and their clinical effect. | 2014 |
2 |
| 16 |
25303639 | Design of enzymatically cleavable prodrugs of a potent platinum-containing anticancer agent. | 2014 Dec 1 |
2 |
| 17 |
21237253 | Lipopolysaccharide down-regulates carbolesterases 1 and 2 and reduces hydrolysis activity in vitro and in vivo via p38MAPK-NF-κB pathway. | 2011 Mar 25 |
1 |
| 18 |
20623318 | Homology modeling and metabolism prediction of human carboxylesterase-2 using docking analyses by GriDock: a parallelized tool based on AutoDock 4.0. | 2010 Sep |
1 |
| 19 |
17537833 | Interleukin-6 alters the cellular responsiveness to clopidogrel, irinotecan, and oseltamivir by suppressing the expression of carboxylesterases HCE1 and HCE2. | 2007 Sep |
1 |
| 20 |
17640957 | Haplotypes and a novel defective allele of CES2 found in a Japanese population. | 2007 Oct |
2 |
| 21 |
16011259 | [Stereoselectivity of skin carboxylesterase metabolism]. | 2005 Apr |
1 |
| 22 |
12607608 | Comprehensive evaluation of carboxylesterase-2 expression in normal human tissues using tissue array analysis. | 2002 Dec |
1 |
| 23 |
9169443 | Purification and cloning of a broad substrate specificity human liver carboxylesterase that catalyzes the hydrolysis of cocaine and heroin. | 1997 Jun 6 |
1 |
| 24 |
9300133 | Hydrolytic profile for ester- or amide-linkage by carboxylesterases pI 5.3 and 4.5 from human liver. | 1997 Aug |
1 |
| 25 |
8930175 | Metabolism of cocaine and heroin is catalyzed by the same human liver carboxylesterases. | 1996 Nov |
1 |