| 1 |
33512760 | Comprehensive analysis of the immunomodulatory effects of rapamycin on human T cells in graft-versus-host disease prophylaxis. | 2021 Aug |
6 |
| 2 |
32311015 | IL-2 enhances ex vivo-expanded regulatory T-cell persistence after adoptive transfer. | 2020 Apr 28 |
4 |
| 3 |
33031791 | Rapamycin as a potential repurpose drug candidate for the treatment of COVID-19. | 2020 Nov 1 |
1 |
| 4 |
33327544 | Acute Conditioning of Antigen-Expanded CD8+ T Cells via the GSK3β-mTORC Axis Differentially Dictates Their Immediate and Distal Responses after Antigen Rechallenge. | 2020 Dec 14 |
1 |
| 5 |
30842775 | Galectin-9 Mediates HIV Transcription by Inducing TCR-Dependent ERK Signaling. | 2019 |
1 |
| 6 |
31484501 | Low dose of IL-2 combined with rapamycin restores and maintains the long-term balance of Th17/Treg cells in refractory SLE patients. | 2019 Sep 4 |
1 |
| 7 |
27651429 | Frontline Science: Placenta-derived decidual stromal cells alter IL-2R expression and signaling in alloantigen-activated T cells. | 2017 Mar |
2 |
| 8 |
26873994 | Metabolic Reprogramming Supports IFN-γ Production by CD56bright NK Cells. | 2016 Mar 15 |
1 |
| 9 |
27350635 | Th1, Th2 and Th17 Cytokine Profile in Patients with Multiple Sclerosis Following Treatment with Rapamycin. | 2016 Jun |
1 |
| 10 |
23689085 | A randomized, open-label study of sirolimus versus cyclosporine in primary de novo renal allograft recipients. | 2013 May 27 |
1 |
| 11 |
24252673 | [The therapeutic mechanisms of sirolimus treatment for ischemic-type biliary lesions after liver transplantation]. | 2013 Aug |
2 |
| 12 |
21722526 | [The influence of rapamycin on BTLA expression of human peripheral blood T lymphocytes]. | 2011 Jul |
1 |
| 13 |
18841360 | Apoptosis of CD4(+)CD25(high) T cells in response to Sirolimus requires activation of T cell receptor and is modulated by IL-2. | 2009 Jun |
4 |
| 14 |
18313267 | Combination of rapamycin and IL-2 increases de novo induction of human CD4(+)CD25(+)FOXP3(+) T cells. | 2008 Jun |
1 |
| 15 |
17000002 | A humanized monoclonal antibody against interleukin-2 that can inactivate the cytokine/receptor complex. | 2007 Mar |
2 |
| 16 |
17182569 | Selective survival of naturally occurring human CD4+CD25+Foxp3+ regulatory T cells cultured with rapamycin. | 2007 Jan 1 |
1 |
| 17 |
17565322 | Interleukin-21: an interleukin-2 dependent player in rejection processes. | 2007 Jun 15 |
3 |
| 18 |
17880416 | Effects of ciclosporin A, tacrolimus and sirolimus on cytokine production in neonatal immune cells. | 2007 Oct |
1 |
| 19 |
16493028 | Prolonged TCR/CD28 engagement drives IL-2-independent T cell clonal expansion through signaling mediated by the mammalian target of rapamycin. | 2006 Mar 1 |
1 |
| 20 |
15643982 | Rapamycin-treated, alloantigen-pulsed host dendritic cells induce ag-specific T cell regulation and prolong graft survival. | 2005 Feb |
1 |
| 21 |
14766378 | Pharmacologic immunosuppression. | 2004 Jan 1 |
1 |
| 22 |
12835079 | The mosaic of immunosuppressive drugs. | 2003 Jul |
1 |
| 23 |
14605212 | Distinct pathways involving the FK506-binding proteins 12 and 12.6 underlie IL-2-versus IL-15-mediated proliferation of T cells. | 2003 Nov 25 |
1 |
| 24 |
11805719 | Protein ubiquitin is an immunophilin. | 2002 Feb |
1 |
| 25 |
12036883 | Effect of rapamycin on the cyclosporin A-resistant CD28-mediated costimulatory pathway. | 2002 Jun 15 |
1 |
| 26 |
11207273 | Uncoupling p70(s6) kinase activation and proliferation: rapamycin-resistant proliferation of human CD8(+) T lymphocytes. | 2001 Mar 1 |
2 |
| 27 |
11390463 | Sanglifehrin A, a novel cyclophilin-binding compound showing immunosuppressive activity with a new mechanism of action. | 2001 Jun 15 |
1 |
| 28 |
10706056 | Stimulated response of peripheral lymphocytes may distinguish cyclosporine effect in renal transplant recipients receiving a cyclosporine+rapamycin regimen. | 2000 Feb 15 |
2 |
| 29 |
10711524 | Sirolimus: a new agent for prevention of renal allograft rejection. | 2000 Mar 1 |
1 |
| 30 |
10985305 | HIV-Nef enhances interleukin-2 production and phosphatidylinositol 3-kinase activity in a human T cell line. | 2000 Aug 18 |
1 |
| 31 |
10072524 | Inhibition of cell cycle progression by rapamycin induces T cell clonal anergy even in the presence of costimulation. | 1999 Mar 1 |
1 |
| 32 |
10227994 | Cell cycle-dependent regulation of FLIP levels and susceptibility to Fas-mediated apoptosis. | 1999 May 1 |
2 |
| 33 |
9864662 | New immunosuppressive strategies. | 1998 Nov |
1 |
| 34 |
9045922 | T cell sensitivity to HLA class I-mediated apoptosis is dependent on interleukin-2 and interleukin-4. | 1997 Feb |
1 |
| 35 |
9182578 | Two discrete regions of interleukin-2 (IL2) receptor beta independently mediate IL2 activation of a PD98059/rapamycin/wortmannin-insensitive Stat5a/b serine kinase. | 1997 Jun 13 |
4 |
| 36 |
9237106 | Induction of IL-5 expression by IL-2 is resistant to the immunosuppressive agents cyclosporin A and rapamycin. | 1997 Jul |
1 |
| 37 |
8594303 | Mechanism of action of the immunosuppressant rapamycin. | 1996 |
1 |
| 38 |
8660826 | Cell cycle progression out of G1 sensitizes primary-cultured nontransformed T cells to TCR-mediated apoptosis. | 1996 Jun 15 |
1 |
| 39 |
8906804 | Human T cells require IL-2 but not G1/S transition to acquire susceptibility to Fas-mediated apoptosis. | 1996 Nov 15 |
1 |
| 40 |
8955182 | IL-2 induces beta2-integrin adhesion via a wortmannin/LY294002-sensitive, rapamycin-resistant pathway. Phosphorylation of a 125-kilodalton protein correlates with induction of adhesion, but not mitogenesis. | 1996 Dec 15 |
2 |
| 41 |
7528328 | Activation of pp70/85 S6 kinases in interleukin-2-responsive lymphoid cells is mediated by phosphatidylinositol 3-kinase and inhibited by cyclic AMP. | 1995 Jan |
2 |
| 42 |
7879050 | Effect of rapamycin on the in vitro release of soluble interleukin-2 receptor by phytohemagglutinin, phorbol myristate acetate, and ionomycin-activated peripheral blood mononuclear cells. | 1995 Feb |
1 |
| 43 |
7995960 | Regulation of cAMP-responsive enhancer binding proteins during cell cycle progression in T lymphocytes stimulated by IL-2. | 1995 Jan 1 |
2 |
| 44 |
8557519 | Interleukin-2 receptor (CD25) upregulation on human T-lymphocytes: sensitivity to immunosuppressants is defined by the mode of T-lymphocyte activation. | 1995 Sep |
1 |
| 45 |
7523510 | Endothelial cell-induced resistance to cyclosporin A in human peripheral blood T cells requires contact-dependent interactions involving CD2 but not CD28. | 1994 Nov 1 |
1 |
| 46 |
7923750 | Cyclosporine: mechanisms of action and toxicity. | 1994 Jul-Aug |
1 |
| 47 |
7974715 | Evidence that rapamycin inhibits interleukin-12-induced proliferation of activated T lymphocytes. | 1994 Nov 27 |
1 |
| 48 |
8004821 | Effects of cyclosporine and rapamycin on immunoglobulin production by preactivated human B cells. | 1994 Jun |
1 |
| 49 |
8254211 | IL-2-induced expression of TTK, a serine, threonine, tyrosine kinase, correlates with cell cycle progression. | 1994 Jan 1 |
1 |
| 50 |
7507316 | Immunosuppressants: tools to investigate the physiological role of cytokines. | 1993 Nov |
1 |