Tacrolimus

interleukin 2 ; Homo sapiens







135 Article(s)
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Title
Pub. Year
#Total Relationships
101 8112299 Calcineurin acts in synergy with PMA to inactivate I kappa B/MAD3, an inhibitor of NF-kappa B. 1994 Feb 15 1
102 8186461 Calcineurin potentiates activation of the granulocyte-macrophage colony-stimulating factor gene in T cells: involvement of the conserved lymphokine element 0. 1994 Jan 1
103 8302298 Functional expression of human CD28 in murine T cell hybridomas. 1994 Jan 1
104 11271304 FK 506 and cyclosporin each block antigen-induced T cell receptor signalling that is dependent on CD4 co-receptor and operates in the absence of detectable cytoplasmic calcium fluxes. 1994 2
105 7507316 Immunosuppressants: tools to investigate the physiological role of cytokines. 1993 Nov 1
106 7683641 FKBP12-FK506 complex inhibits phosphatase activity of two mammalian isoforms of calcineurin irrespective of their substrates or activation mechanisms. 1993 Mar 1
107 7689811 FK-506 inhibits the IL-2-independent induction of the activation antigen CD 69. 1993 Jun 23 1
108 8397339 The T-cell transcription factor NFATp is a substrate for calcineurin and interacts with Fos and Jun. 1993 Sep 23 1
109 1281674 FK506 and rapamycin selectively enhance degradation of IL-2 and GM-CSF mRNA. 1992 Oct 3
110 1355105 CD2-mediated autocrine growth of herpes virus saimiri-transformed human T lymphocytes. 1992 Sep 1 1
111 1371491 Effects of FK506 and cyclosporin A on cytokine production studied in vitro at a single-cell level. 1992 Jan 2
112 1371623 Blockade of interleukin-2 production from cloned T cells by cyclosporine and FK 506 assessed by proliferation assays in vitro. 1992 Feb 1
113 1371624 Enhanced liver regeneration by FK 506 can be blocked by interleukin-1 alpha and interleukin-2. 1992 Feb 1
114 1373887 Calcineurin phosphatase activity in T lymphocytes is inhibited by FK 506 and cyclosporin A. 1992 May 1 1
115 1374947 FK506 as an agonist to induce inhibition of interleukin 2 production. 1992 May 1
116 1377361 FK-506- and CsA-sensitive activation of the interleukin-2 promoter by calcineurin. 1992 Jun 25 3
117 1378764 Cyclosporin A and FK506 prevent the derepression of the IL-2 gene in mitogen-induced primary T lymphocytes. 1992 Mar 2
118 1380242 SRC-related proto-oncogenes and transcription factors in primary human T cells: modulation by cyclosporin A and FK506. 1992 Apr 3
119 1380951 The effects of the antifungal azoles itraconazole, fluconazole, ketoconazole and miconazole on cytokine gene expression in human lymphoid cells. 1992 Jul 1
120 1384862 The effects of FK-506 and cyclosporin A on the proliferation of PHA-stimulated T cells in response to IL-2, IL-4 or IL-6. 1992 1
121 1707162 The immunosuppressives FK 506 and cyclosporin A inhibit the generation of protein factors binding to the two purine boxes of the interleukin 2 enhancer. 1991 Jan 11 4
122 1707760 FK-506 and cyclosporin A inhibit highly similar signal transduction pathways in human T lymphocytes. 1991 Apr 1 1
123 1712901 The immunosuppressant FK-506 specifically inhibits mitogen-induced activation of the interleukin-2 promoter and the isolated enhancer elements NFIL-2A and NF-AT1. 1991 Aug 5
124 1713361 The immunosuppressive antagonism of low doses of FK506 and cyclosporine. 1991 Jul 1
125 1715185 Cyclosporin A and FK-506 both affect DNA binding of regulatory nuclear proteins to the human interleukin-2 promoter. 1991 Mar 5
126 1715317 Comparison of the effects of FK-506, cyclosporin A and rapamycin on IL-2 production. 1991 Jul 1
127 1717376 The immunosuppressive macrolides FK-506 and rapamycin. 1991 Jul 3
128 1720417 The immunosuppressive agent FK506 inhibits in vitro expression of membrane-bound and soluble interleukin-2 receptors on resting but not on activated human lymphocytes. 1991 Sep 1
129 1721767 [Experimental studies on the mode of action of cyclosporine and FK506 assessed by proliferation response of human cloned T lymphocytes]. 1991 Oct 1
130 1726895 FK506 lacks the ability to inhibit expression of interleukin-2 receptor beta-chain on human lymphocytes. 1991 Sep 1
131 1701570 Evidence that the immunosuppressive effects of FK506 and cyclosporine are identical. 1990 Dec 1
132 1701825 The effect of immunosuppressive agents on the induction of nuclear factors that bind to sites on the interleukin 2 promoter. 1990 Dec 1 1
133 2123553 Two distinct signal transmission pathways in T lymphocytes are inhibited by complexes formed between an immunophilin and either FK506 or rapamycin. 1990 Dec 4
134 2465593 Effect of a new immunosuppressive agent, FK506, on human lymphocyte responses in vitro. II. Inhibition of the production of IL-2 and gamma-IFN, but not B cell-stimulating factor 2. 1989 Feb 2
135 2472451 The immunosuppressant FK506 selectively inhibits expression of early T cell activation genes. 1989 Jul 15 4