| 1 |
35048565 | Pyruvate Facilitates FACT-Mediated γH2AX Loading to Chromatin and Promotes the Radiation Resistance of Glioblastoma. | 2022 Mar |
4 |
| 2 |
35189247 | Objective assessment of adrenocortical carcinoma driver genes and their correlation with tumor pyruvate kinase M2. | 2022 May 15 |
2 |
| 3 |
35610475 | Pyruvate kinase M1 regulates butyrate metabolism in cancerous colonocytes. | 2022 May 24 |
2 |
| 4 |
33473116 | SUMOylation disassembles the tetrameric pyruvate kinase M2 to block myeloid differentiation of leukemia cells. | 2021 Jan 20 |
1 |
| 5 |
33526685 | Absence of retbindin blocks glycolytic flux, disrupts metabolic homeostasis, and leads to photoreceptor degeneration. | 2021 Feb 9 |
2 |
| 6 |
34355179 | Tumor pyruvate kinase M2 modulators: a comprehensive account of activators and inhibitors as anticancer agents. | 2021 Jul 21 |
2 |
| 7 |
32208360 | Endometrial pyruvate kinase M2 is essential for decidualization during early pregnancy. | 2020 Jun |
2 |
| 8 |
32295714 | The cysteine residue at 424th of pyruvate kinase M2 is crucial for tetramerization and responsiveness to oxidative stress. | 2020 Jun 11 |
2 |
| 9 |
32641713 | Oxidized ATM promotes breast cancer stem cell enrichment through energy metabolism reprogram-mediated acetyl-CoA accumulation. | 2020 Jul 3 |
1 |
| 10 |
33125108 | Effects and mechanisms of fatty acid metabolism‑mediated glycolysis regulated by betulinic acid‑loaded nanoliposomes in colorectal cancer. | 2020 Dec |
2 |
| 11 |
33335484 | From Glucose to Lactate and Transiting Intermediates Through Mitochondria, Bypassing Pyruvate Kinase: Considerations for Cells Exhibiting Dimeric PKM2 or Otherwise Inhibited Kinase Activity. | 2020 |
1 |
| 12 |
30866966 | Low levels of pyruvate induced by a positive feedback loop protects cholangiocarcinoma cells from apoptosis. | 2019 Mar 12 |
1 |
| 13 |
29225125 | Interdependence of GLO I and PKM2 in the Metabolic shift to escape apoptosis in GLO I-dependent cancer cells. | 2018 Jan 15 |
1 |
| 14 |
29393401 | Pyruvate kinase type M2 contributes to the development of pancreatic ductal adenocarcinoma by regulating the production of metabolites and reactive oxygen species. | 2018 Mar |
1 |
| 15 |
30700935 | Tumor pyruvate kinase M2: A promising molecular target of gastrointestinal cancer. | 2018 Dec |
2 |
| 16 |
29182273 | Structural Investigation of a Dimeric Variant of Pyruvate Kinase Muscle Isoform 2. | 2017 Dec 19 |
2 |
| 17 |
29312595 | Pyruvate kinase M2 phosphorylates H2AX and promotes genomic instability in human tumor cells. | 2017 Dec 12 |
1 |
| 18 |
27152240 | Extracellular PKM2 induces cancer proliferation by activating the EGFR signaling pathway. | 2016 |
1 |
| 19 |
27810895 | A Novel Role for Pyruvate Kinase M2 as a Corepressor for P53 during the DNA Damage Response in Human Tumor Cells. | 2016 Dec 9 |
1 |
| 20 |
25645022 | Structural insight into mechanisms for dynamic regulation of PKM2. | 2015 Apr |
2 |
| 21 |
24972138 | PKM2: the thread linking energy metabolism reprogramming with epigenetics in cancer. | 2014 Jun 26 |
1 |
| 22 |
25320009 | Changes in pyruvate metabolism detected by magnetic resonance imaging are linked to DNA damage and serve as a sensor of temozolomide response in glioblastoma cells. | 2014 Dec 1 |
1 |
| 23 |
23212076 | Dual roles of PKM2 in cancer metabolism. | 2013 Jan |
2 |
| 24 |
23451252 | Pyruvate kinase M2 expression, but not pyruvate kinase activity, is up-regulated in a grade-specific manner in human glioma. | 2013 |
1 |
| 25 |
23576436 | Reciprocal regulation of protein kinase and pyruvate kinase activities of pyruvate kinase M2 by growth signals. | 2013 May 31 |
2 |
| 26 |
22306293 | Pyruvate kinase M2 regulates gene transcription by acting as a protein kinase. | 2012 Mar 9 |
2 |
| 27 |
22433951 | Death-associated proliferation kinetic in normal and transformed cells. | 2012 Apr 15 |
1 |
| 28 |
23064226 | Serine is a natural ligand and allosteric activator of pyruvate kinase M2. | 2012 Nov 15 |
1 |
| 29 |
21673231 | Enhancing mitochondrial respiration suppresses tumor promoter TPA-induced PKM2 expression and cell transformation in skin epidermal JB6 cells. | 2011 Sep |
1 |
| 30 |
22262476 | Metabolic pathway alterations that support cell proliferation. | 2011 |
1 |
| 31 |
2813362 | Cytosolic thyroid hormone-binding protein is a monomer of pyruvate kinase. | 1989 Oct |
1 |