16 Article(s)Download |
PMID | Title | Pub. Year | #Total Relationships |
1 | 35241524 | PKM2 Is Overexpressed in Glioma Tissues, and Its Inhibition Highly Increases Late Apoptosis in U87MG Cells With Low-density Specificity. | 2022 Mar-Apr | 2 |
2 | 33220292 | Shikonin differentially regulates glucose metabolism via PKM2 and HIF1α to overcome apoptosis in a refractory HCC cell line. | 2021 Jan 15 | 4 |
3 | 34234853 | Shikonin Inhibits Tumor Growth of ESCC by suppressing PKM2 mediated Aerobic Glycolysis and STAT3 Phosphorylation. | 2021 | 5 |
4 | 34348626 | Rationalization of the activity Profile of Pyruvate Kinase Isozyme M2 (PKM2) Inhibitors using 3D QSAR. | 2021 | 3 |
5 | 34354861 | Inhibition of BAG3 enhances the anticancer effect of shikonin in hepatocellular carcinoma. | 2021 | 3 |
6 | 34752817 | Shikonin alleviates choroidal neovascularization by inhibiting proangiogenic factor production from infiltrating macrophages. | 2021 Dec | 4 |
7 | 31819190 | Cutting off the fuel supply to calcium pumps in pancreatic cancer cells: role of pyruvate kinase-M2 (PKM2). | 2020 Jan | 2 |
8 | 32487192 | PKM2 inhibition may reverse therapeutic resistance to transarterial chemoembolization in hepatocellular carcinoma. | 2020 Jun 3 | 1 |
9 | 32774157 | TET2 suppresses nasopharyngeal carcinoma progression by inhibiting glycolysis metabolism. | 2020 | 1 |
10 | 32878800 | Antitumor Effect of Shikonin, a PKM2 Inhibitor, in Cholangiocarcinoma Cell Lines. | 2020 Sep | 2 |
11 | 30911326 | Combination of shikonin with paclitaxel overcomes multidrug resistance in human ovarian carcinoma cells in a P-gp-independent manner through enhanced ROS generation. | 2019 | 3 |
12 | 31246990 | Tumor M2-PK: A novel urine marker of bladder cancer. | 2019 | 4 |
13 | 29185365 | Synthesis and antitumor activity of novel 2, 3-didithiocarbamate substituted naphthoquinones as inhibitors of pyruvate kinase M2 isoform. | 2018 Dec | 1 |
14 | 29608987 | RIP1 and RIP3 contribute to shikonin-induced glycolysis suppression in glioma cells via increase of intracellular hydrogen peroxide. | 2018 Jul 1 | 1 |
15 | 24710512 | Sensitizing the therapeutic efficacy of taxol with shikonin in human breast cancer cells. | 2014 | 2 |
16 | 25587028 | Ferroxitosis: a cell death from modulation of oxidative phosphorylation and PKM2-dependent glycolysis in melanoma. | 2014 Dec 30 | 1 |