| 1 |
35098839 | Mutyh deficiency downregulates mitochondrial fusion proteins and causes cardiac dysfunction via α-ketoglutaric acid reduction with oxidative stress. | 2022 Feb |
1 |
| 2 |
34142156 | Structure of the mammalian adenine DNA glycosylase MUTYH: insights into the base excision repair pathway and cancer. | 2021 Jul 9 |
2 |
| 3 |
34970419 | MUTYH Actively Contributes to Microglial Activation and Impaired Neurogenesis in the Pathogenesis of Alzheimer's Disease. | 2021 |
2 |
| 4 |
32664726 | Detection of OG:A Lesion Mispairs by MutY Relies on a Single His Residue and the 2-Amino Group of 8-Oxoguanine. | 2020 Aug 5 |
1 |
| 5 |
32991318 | An ordered assembly of MYH glycosylase, SIRT6 protein deacetylase, and Rad9-Rad1-Hus1 checkpoint clamp at oxidatively damaged telomeres. | 2020 Sep 29 |
2 |
| 6 |
33145410 | Designer Fluorescent Adenines Enable Real-Time Monitoring of MUTYH Activity. | 2020 Oct 28 |
3 |
| 7 |
29209987 | Genetic Investigation of Polymorphic OGG1 and MUTYH Genes Towards Increased Susceptibility in Lung Adenocarcinoma and its Impact on Overall Survival of Lung Cancer Patients Treated with Platinum Based Chemotherapy. | 2019 Oct |
1 |
| 8 |
31203172 | When you're strange: Unusual features of the MUTYH glycosylase and implications in cancer. | 2019 Aug |
1 |
| 9 |
29746241 | Fe-S Clusters and MutY Base Excision Repair Glycosylases: Purification, Kinetics, and DNA Affinity Measurements. | 2018 |
1 |
| 10 |
29746250 | Cellular Assays for Studying the Fe-S Cluster Containing Base Excision Repair Glycosylase MUTYH and Homologs. | 2018 |
1 |
| 11 |
29915346 | A human MUTYH variant linking colonic polyposis to redox degradation of the [4Fe4S]2+ cluster. | 2018 Aug |
1 |
| 12 |
30208271 | The Zinc Linchpin Motif in the DNA Repair Glycosylase MUTYH: Identifying the Zn2+ Ligands and Roles in Damage Recognition and Repair. | 2018 Oct 17 |
3 |
| 13 |
27253753 | Reduced expression of the DNA glycosylase gene MUTYH is associated with an increased number of somatic mutations via a reduction in the DNA repair capacity in prostate adenocarcinoma. | 2017 Feb |
1 |
| 14 |
27890638 | Aberrant base excision repair pathway of oxidatively damaged DNA: Implications for degenerative diseases. | 2017 Jun |
1 |
| 15 |
28087410 | Repair of 8-oxoG:A mismatches by the MUTYH glycosylase: Mechanism, metals and medicine. | 2017 Jun |
1 |
| 16 |
28551381 | A Specific Mutational Signature Associated with DNA 8-Oxoguanine Persistence in MUTYH-defective Colorectal Cancer. | 2017 Jun |
1 |
| 17 |
29098062 | Mutation Spectrum Induced by 8-Bromoguanine, a Base Damaged by Reactive Brominating Species, in Human Cells. | 2017 |
1 |
| 18 |
26673696 | Structure and stereochemistry of the base excision repair glycosylase MutY reveal a mechanism similar to retaining glycosidases. | 2016 Jan 29 |
3 |
| 19 |
26312135 | A physical association between the human mutY homolog (hMYH) and DNA topoisomerase II-binding protein 1 (hTopBP1) regulates Chk1-induced cell cycle arrest in HEK293 cells. | 2015 |
1 |
| 20 |
26377631 | Distinct functional consequences of MUTYH variants associated with colorectal cancer: Damaged DNA affinity, glycosylase activity and interaction with PCNA and Hus1. | 2015 Oct |
2 |
| 21 |
26576226 | Regulation of MUTYH, a DNA Repair Enzyme, in Renal Proximal Tubular Epithelial Cells. | 2015 |
1 |
| 22 |
24315136 | Mammalian MutY homolog (MYH or MUTYH) protects cells from oxidative DNA damage. | 2014 Jan |
2 |
| 23 |
24569162 | Genetic instability in lymphoblastoid cell lines expressing biallelic and monoallelic variants in the human MUTYH gene. | 2014 Jul 15 |
1 |
| 24 |
23108399 | Loss of MUTYH function in human cells leads to accumulation of oxidative damage and genetic instability. | 2013 Sep 19 |
1 |
| 25 |
23507534 | Role of MUTYH in human cancer. | 2013 Mar-Apr |
1 |
| 26 |
24209961 | Coordination of MYH DNA glycosylase and APE1 endonuclease activities via physical interactions. | 2013 Dec |
1 |
| 27 |
22444586 | For MutY, it's all about the OG. | 2012 Mar 23 |
1 |
| 28 |
22469746 | Association between polymorphisms of the DNA base excision repair genes MUTYH and hOGG1 and age-related macular degeneration. | 2012 May |
1 |
| 29 |
22641385 | Alterations of the base excision repair gene MUTYH in sporadic colorectal cancer. | 2012 Aug |
1 |
| 30 |
22926731 | Cancer-associated variants and a common polymorphism of MUTYH exhibit reduced repair of oxidative DNA damage using a GFP-based assay in mammalian cells. | 2012 Nov |
2 |
| 31 |
21235684 | DNA glycosylase encoded by MUTYH functions as a molecular switch for programmed cell death under oxidative stress to suppress tumorigenesis. | 2011 Apr |
2 |
| 32 |
21279954 | Common genetic variants of MUTYH are not associated with cutaneous malignant melanoma: application of molecular screening by means of high-resolution melting technique in a pilot case-control study. | 2011 Jan-Mar |
1 |
| 33 |
21826668 | Reduced expression of MUTYH with suppressive activity against mutations caused by 8-hydroxyguanine is a novel predictor of a poor prognosis in human gastric cancer. | 2011 Nov |
2 |
| 34 |
20418187 | Functional analysis of MUTYH mutated proteins associated with familial adenomatous polyposis. | 2010 Jun 4 |
1 |
| 35 |
20724227 | Ser 524 is a phosphorylation site in MUTYH and Ser 524 mutations alter 8-oxoguanine (OG): a mismatch recognition. | 2010 Oct 5 |
1 |
| 36 |
20816984 | A structural hinge in eukaryotic MutY homologues mediates catalytic activity and Rad9-Rad1-Hus1 checkpoint complex interactions. | 2010 Oct 29 |
1 |
| 37 |
20848659 | Adenine DNA glycosylase activity of 14 human MutY homolog (MUTYH) variant proteins found in patients with colorectal polyposis and cancer. | 2010 Nov |
1 |
| 38 |
19300419 | Polymorphisms of the DNA base excision repair gene MUTYH in head and neck cancer. | 2009 Mar |
1 |
| 39 |
19443904 | Catalytically impaired hMYH and NEIL1 mutant proteins identified in patients with primary sclerosing cholangitis and cholangiocarcinoma. | 2009 Jul |
2 |
| 40 |
19479711 | Altered expression of MUTYH and an increase in 8-hydroxydeoxyguanosine are early events in ulcerative colitis-associated carcinogenesis. | 2009 Sep |
2 |
| 41 |
19513679 | Construction and characterization of a cell line deficient in repair of mitochondrial, but not nuclear, oxidative DNA damage. | 2009 |
1 |
| 42 |
19836313 | Adenine removal activity and bacterial complementation with the human MutY homologue (MUTYH) and Y165C, G382D, P391L and Q324R variants associated with colorectal cancer. | 2009 Dec 3 |
4 |
| 43 |
18271935 | Association between genetic polymorphisms of the base excision repair gene MUTYH and increased colorectal cancer risk in a Japanese population. | 2008 Feb |
1 |
| 44 |
17081686 | Functional characterization of human MutY homolog (hMYH) missense mutation (R231L) that is linked with hMYH-associated polyposis. | 2007 May 18 |
1 |
| 45 |
17161978 | MUTYH-associated polyposis--from defect in base excision repair to clinical genetic testing. | 2007 Mar 1 |
1 |
| 46 |
17279544 | Oxidative damage in nucleic acids and Parkinson's disease. | 2007 Apr |
1 |
| 47 |
17425590 | Significance of error-avoiding mechanisms for oxidative DNA damage in carcinogenesis. | 2007 Apr |
1 |
| 48 |
17638869 | MUTYH-null mice are susceptible to spontaneous and oxidative stress induced intestinal tumorigenesis. | 2007 Jul 15 |
1 |
| 49 |
16720376 | MutY and MutY homologs (MYH) in genome maintenance. | 2006 Sep 1 |
2 |
| 50 |
16773329 | Up-regulation of hMUTYH, a DNA repair enzyme, in the mitochondria of substantia nigra in Parkinson's disease. | 2006 Aug |
1 |