Leukotriene A4

arachidonate 5-lipoxygenase ; Homo sapiens







28 Article(s)
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1 27033421 Impact of simultaneous stimulation of 5-lipoxygenase and myeloperoxidase in human neutrophils. 2016 Apr 1
2 27477678 Development of smart cell-free and cell-based assay systems for investigation of leukotriene C4 synthase activity and evaluation of inhibitors. 2016 Nov 1
3 24893149 ATP allosterically activates the human 5-lipoxygenase molecular mechanism of arachidonic acid and 5(S)-hydroperoxy-6(E),8(Z),11(Z),14(Z)-eicosatetraenoic acid. 2014 Jul 15 2
4 17376394 Development of a fluorescence-based enzyme assay of human 5-lipoxygenase. 2007 May 15 2
5 15342681 Fatty acid binding proteins stabilize leukotriene A4: competition with arachidonic acid but not other lipoxygenase products. 2004 Nov 2
6 11796736 Molecular basis of the specific subcellular localization of the C2-like domain of 5-lipoxygenase. 2002 Apr 12 2
7 11802780 Nuclear-localization-signal-dependent and nuclear-export-signal-dependent mechanisms determine the localization of 5-lipoxygenase. 2002 Feb 1 2
8 10864449 Covalent binding of LTA(4) to nucleosides and nucleotides. 2000 Jul 1 2
9 11087405 Alterations in leukotriene synthase activity of the human 5-lipoxygenase by site-directed mutagenesis affecting its positional specificity. 2000 Nov 28 2
10 10591081 The biology of 5-lipoxygenase: function, structure, and regulatory mechanisms. 1999 Nov-Dec 1
11 9609696 Calcium is not required for 5-lipoxygenase activity at high phosphatidyl choline vesicle concentrations. 1998 Jun 2 1
12 9620944 Cell biology of the 5-lipoxygenase pathway 1998 Jun 1
13 9647604 Cell biology of the 5-lipoxygenase pathway. 1998 Jun 2
14 7840802 Enhancement of leukotriene A4 biosynthesis in neutrophils from patients with rheumatoid arthritis after a single glucocorticoid dose. 1995 Jan 18 1
15 7929400 Eosinophil 15-lipoxygenase is a leukotriene A4 synthase. 1994 Oct 28 2
16 7938075 5-Lipoxygenase: enzyme expression and regulation of activity. 1994 Jul 1
17 8300592 Irreversible inactivation of 5-lipoxygenase by leukotriene A4. Characterization of product inactivation with purified enzyme and intact leukocytes. 1994 Jan 28 7
18 8215451 Identification of 5-keto-(7E,9E,11Z,14Z)-eicosatetraenoic acid as a novel nonenzymatic rearrangement product of leukotriene A4. 1993 Nov 1 2
19 8269937 Coupling of recombinant 5-lipoxygenase and leukotriene A4 hydrolase activities and transcellular metabolism of leukotriene A4 in Sf9 insect cells. 1993 Dec 1 1
20 8395245 Interfacial catalysis and production of a high ratio of leukotriene A4 to 5-HPETE by 5-lipoxygenase in a coupled assay with phospholipase A2. 1993 Mar-Apr 1
21 1429555 Reversible membrane association of neutrophil 5-lipoxygenase is accompanied by retention of activity and a change in substrate specificity. 1992 Nov 5 1
22 1848236 Characterization of the activity of purified recombinant human 5-lipoxygenase in the absence and presence of leukocyte factors. 1991 Mar 15 1
23 2300172 Identification and isolation of a membrane protein necessary for leukotriene production. 1990 Jan 18 1
24 2649885 Native and mutant 5-lipoxygenase expression in a baculovirus/insect cell system. 1989 Apr 1
25 3036460 An elucidation of the arachidonic acid cascade. Discovery of prostaglandins, thromboxane and leukotrienes. 1987 1
26 3006030 Single protein from human leukocytes possesses 5-lipoxygenase and leukotriene A4 synthase activities. 1986 Feb 1
27 3020619 Stereoselective hydrogen abstraction in leukotriene A4 synthesis by purified 5-lipoxygenase of porcine leukocytes. 1986 Jul 1
28 6811315 Selective inhibition of 5-lipoxygenase by 5,6-methanoleukotriene A4, a stable analogue of leukotriene A4. 1982 Jun 21 1