Eicosapentaenoic Acid

arachidonate 5-lipoxygenase ; Homo sapiens







15 Article(s)
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1 32841762 Human lipoxygenase isoforms form complex patterns of double and triple oxygenated compounds from eicosapentaenoic acid. 2020 Dec 3
2 31664810 Mutations of Triad Determinants Changes the Substrate Alignment at the Catalytic Center of Human ALOX5. 2019 Dec 20 2
3 28892009 Nrf2 Activation by 5-lipoxygenase Metabolites in Human Umbilical Vascular Endothelial Cells. 2017 Sep 11 2
4 27044314 Effect of n-3 fatty acids on the expression of inflammatory genes in THP-1 macrophages. 2016 Apr 5 4
5 23351835 Adipose tissue arachidonic acid content is associated with the expression of 5-lipoxygenase in atherosclerotic plaques. 2013 Jan 25 1
6 20558833 Genetic variants in the metabolism of omega-6 and omega-3 fatty acids: their role in the determination of nutritional requirements and chronic disease risk. 2010 Jul 2
7 12573452 Inhibition by eicosapentaenoic acid of IL-1beta-induced PGHS-2 expression in human microvascular endothelial cells: involvement of lipoxygenase-derived metabolites and p38 MAPK pathway. 2003 Feb 20 2
8 11895160 Impact of n-3 fatty acid supplemented parenteral nutrition on haemostasis patterns after major abdominal surgery. 2002 Jan 1
9 8468488 Effects of exogenous eicosapentaenoic acid on generation of leukotriene C4 and leukotriene C5 by calcium ionophore-activated human eosinophils in vitro. 1993 Apr 15 2
10 1311589 Inhibition of human neutrophil leukotriene B4 synthesis by combination auranofin and eicosapentaenoic acid. 1992 Feb 18 1
11 1569925 Ligand-operated synthesis of 4-series and 5-series leukotrienes in human neutrophils: critical dependence on exogenous free fatty acid supply. 1992 Apr 2
12 2116491 Platelet-neutrophil interactions. 12S,20- and 5S,12S-dihydroxyeicosapentaenoic acids: two novel neutrophil metabolites from platelet-derived 12S-hydroxyeicosapentaenoic acid. 1990 May 1
13 2550490 The metabolism of arachidonic and eicosapentaenoic acids in human neutrophils stimulated by A23187 and FMLP. 1989 Jul 1
14 3036459 The role of arachidonic acid metabolites in local and systemic inflammatory processes. 1987 2
15 6096644 The leukotrienes. 1984 1