Levodopa

dopa decarboxylase ; Rattus norvegicus







80 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 34313482 Pancreatic acinar cells utilize tyrosine to synthesize L-dihydroxyphenylalanine. 2021 Dec 1
2 28166239 Depletion of AADC activity in caudate nucleus and putamen of Parkinson's disease patients; implications for ongoing AAV2-AADC gene therapy trial. 2017 2
3 28787702 β-asarone and levodopa coadministration increases striatal levels of dopamine and levodopa and improves behavioral competence in Parkinson's rat by enhancing dopa decarboxylase activity. 2017 Oct 1
4 26830512 Production of Dopamine by Aromatic l-Amino Acid Decarboxylase Cells after Spinal Cord Injury. 2016 Jun 15 6
5 26622527 Dynamic changes of five neurotransmitters and their related enzymes in various rat tissues following β-asarone and levodopa co-administration. 2015 Oct 2
6 24997271 Neurons expressing individual enzymes of dopamine synthesis in the mediobasal hypothalamus of adult rats: functional significance and topographic interrelations. 2014 Sep 26 3
7 23196068 L-dopa-induced dopamine synthesis and oxidative stress in serotonergic cells. 2013 Apr 2
8 22236652 Benserazide dosing regimen affects the response to L-3,4-dihydroxyphenylalanine in the 6-hydroxydopamine-lesioned rat. 2012 Apr 3
9 20407462 Microdialysis with radiometric monitoring of L-[β-11C]DOPA to assess dopaminergic metabolism: effect of inhibitors of L-amino acid decarboxylase, monoamine oxidase, and catechol-O-methyltransferase on rat striatal dialysate. 2011 Jan 4
10 20542064 Locomotor response to L-DOPA in reserpine-treated rats following central inhibition of aromatic L-amino acid decarboxylase: further evidence for non-dopaminergic actions of L-DOPA and its metabolites. 2010 Sep 3
11 19449783 [Monoamine synthesis by non-monoaminergic neurons: illusion of reality]. 2009 Mar 1
12 17920284 Intrastriatal inhibition of aromatic amino acid decarboxylase prevents l-DOPA-induced dyskinesia: a bilateral reverse in vivo microdialysis study in 6-hydroxydopamine lesioned rats. 2008 Feb 1
13 18602388 Induction of dopamine biosynthesis by l-DOPA in PC12 cells: implications of L-DOPA influx and cyclic AMP. 2008 Sep 4 4
14 17241115 In vivo induction of heat shock proteins in the substantia nigra following L-DOPA administration is associated with increased activity of mitochondrial complex I and nitrosative stress in rats: regulation by glutathione redox state. 2007 May 1
15 17259019 Effects of 2,3-benzodiazepine AMPA receptor antagonists on dopamine turnover in the striatum of rats with experimental parkinsonism. 2007 Mar 15 1
16 16182609 Viral-mediated temporally controlled dopamine production in a rat model of Parkinson disease. 2006 Jan 9
17 16269145 Vesicular monoamine transporter-2 and aromatic L-amino acid decarboxylase gene therapy prevents development of motor complications in parkinsonian rats after chronic intermittent L-3,4-dihydroxyphenylalanine administration. 2006 Jan 2
18 16504219 L-3,4-dihydroxyphenylalanine-induced c-Fos expression in the CNS under inhibition of central aromatic L-amino acid decarboxylase. 2006 Jun 7
19 15836622 Adeno-associated virus-mediated gene transfer of human aromatic L-amino acid decarboxylase protects mixed striatal primary cultures from L-DOPA toxicity. 2005 May 2
20 14701706 Augmentation of endogenous dopamine production increases lung liquid clearance. 2004 Mar 15 2
21 14980733 Dopamine synthesis by non-dopaminergic neurons expressing individual complementary enzymes of the dopamine synthetic pathway in the arcuate nucleus of fetal rats. 2004 5
22 15380638 Evaluation of rat striatal L-dopa and DA concentration after intraperitoneal administration of L-dopa prodrugs in liposomal formulations. 2004 Sep 30 4
23 15462205 [Dopamine synthesis by non-dopaminergic neurons of the rat fetus arquate nucleus]. 2004 Jul 1
24 12676374 Localization and functional significance of striatal neurons immunoreactive to aromatic L-amino acid decarboxylase or tyrosine hydroxylase in rat Parkinsonian models. 2003 Apr 18 3
25 12703659 Effects of benserazide on L-DOPA-derived extracellular dopamine levels and aromatic L-amino acid decarboxylase activity in the striatum of 6-hydroxydopamine-lesioned rats. 2003 Mar 3
26 14565778 The parkinsonian neurotoxin 1-methyl-4-phenylpyridinium (MPP(+)) mediates release of l-3,4-dihydroxyphenylalanine (l-DOPA) and inhibition of l-DOPA decarboxylase in the rat striatum: a microdialysis study. 2003 Oct 3
27 11965353 Tyrosine hydroxylase- and/or aromatic L-amino acid decarboxylase-expressing neurons in the rat arcuate nucleus: ontogenesis and functional significance. 2002 Jul 1
28 12047348 Circadian rhythm of aromatic L-amino acid decarboxylase in the rat suprachiasmatic nucleus: gene expression and decarboxylating activity in clock oscillating cells. 2002 May 1
29 12358737 A site-specific mutation of tyrosine hydroxylase reduces feedback inhibition by dopamine in genetically modified cells grafted in parkinsonian rats. 2002 Oct 4
30 11135014 The central aromatic amino acid DOPA decarboxylase inhibitor, NSD-1015, does not inhibit L-DOPA-induced circling in unilateral 6-OHDA-lesioned-rats. 2001 Jan 2
31 11295535 Selective dopaminergic vulnerability: 3,4-dihydroxyphenylacetaldehyde targets mitochondria. 2001 Apr 15 2
32 11436352 Gene therapy for Parkinson's disease: determining the genes necessary for optimal dopamine replacement in rat models. 2001 Mar 3
33 11587490 A pharmacokinetic model to predict the PK interaction of L-dopa and benserazide in rats. 2001 Aug 1
34 10619466 Dual effects of L-3,4-dihydroxyphenylalanine on aromatic L-amino acid decarboxylase, dopamine release and motor stimulation in the reserpine-treated rat: evidence that behaviour is dopamine independent. 2000 3
35 10773222 The O-methylated derivative of L-DOPA, 3-O-methyl-L-DOPA, fails to inhibit neuronal and non-neuronal aromatic L-amino acid decarboxylase. 2000 Apr 28 2
36 10869844 Striatal cells containing aromatic L-amino acid decarboxylase: an immunohistochemical comparison with other classes of striatal neurons. 2000 1
37 11144954 The localization and functional contribution of striatal aromatic L-amino acid decarboxylase to L-3,4-dihydroxyphenylalanine decarboxylation in rodent parkinsonian models. 2000 Sep-Oct 1
38 10027744 Caco-2 cells in culture synthesize and degrade dopamine and 5-hydroxytryptamine: a comparison with rat jejunal epithelial cells. 1999 1
39 10191339 Vesicular monoamine transporter-2 and aromatic L-amino acid decarboxylase enhance dopamine delivery after L-3, 4-dihydroxyphenylalanine administration in Parkinsonian rats. 1999 Apr 15 1
40 9555017 Serotonergic activity in the rat striatum after intrastriatal transplantation of fetal nigra as measured by microdialysis. 1998 Mar 30 2
41 9591841 [3H]DOPA formed from [3H]tyrosine in living rat brain is not committed to dopamine synthesis. 1998 May 5
42 9710269 Amantadine increases aromatic L-amino acid decarboxylase mRNA in PC12 cells. 1998 Aug 15 3
43 9853519 Behavioral recovery in 6-hydroxydopamine-lesioned rats by cotransduction of striatum with tyrosine hydroxylase and aromatic L-amino acid decarboxylase genes using two separate adeno-associated virus vectors. 1998 Nov 20 2
44 9871440 Effects of glutamate antagonists on the activity of aromatic L-amino acid decarboxylase. 1998 2
45 10343976 L-deprenyl induces aromatic L-amino acid decarboxylase (AADC) mRNA in the rat substantia nigra and ventral tegmentum. An in situ hybridization study. 1998 Aug-Dec 1
46 9349551 Role of aromatic L-amino acid decarboxylase for dopamine replacement by genetically modified fibroblasts in a rat model of Parkinson's disease. 1997 Nov 2
47 9367815 Expression, purification, and characterization of rat aromatic L-amino acid decarboxylase in Escherichia coli. 1997 Nov 1
48 8750961 Aromatic L-amino acid decarboxylase immunoreactive cells in the rat striatum: a possible site for the conversion of exogenous L-DOPA to dopamine. 1995 Dec 15 6
49 7697371 Immunohistochemical evidence that central serotonin neurons produce dopamine from exogenous L-DOPA in the rat, with reference to the involvement of aromatic L-amino acid decarboxylase. 1994 Dec 26 5
50 8108317 Dopamine synthesis, uptake and metabolism in embryonic rat mesencephalic cultures. 1993 Oct-Nov 1