tofacitinib

interferon gamma ; Homo sapiens







32 Article(s)
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1 35297512 Suppression of IL-12/IL-23 p40 subunit in the skin and blood of psoriasis patients by Tofacitinib is dependent on active interferon-γ signaling in dendritic cells: Implications for the treatment of psoriasis and interferon-driven diseases. 2022 Jun 5
2 35536531 Tofacitinib enhances IGF1 via inhibiting STAT6 transcriptionally activated-miR-425-5p to ameliorate inflammation in RA-FLS. 2022 May 10 1
3 33317858 Treatment of granuloma annulare and suppression of proinflammatory cytokine activity with tofacitinib. 2021 May 1
4 33491334 Tofacitinib overcomes an IFNγ-induced decrease in NK cell-mediated cytotoxicity via the regulation of immune-related molecules in LC-2/ad. 2021 Mar 7
5 33705988 Loss of sarcomeric proteins via upregulation of JAK/STAT signaling underlies interferon-γ-induced contractile deficit in engineered human myocardium. 2021 May 1
6 33899926 Lymphocyte modulation by tofacitinib in patients with rheumatoid arthritis. 2021 Aug 1
7 34107055 Tofacitinib therapy intercepts macrophage metabolic reprogramming instigated by SARS-CoV-2 Spike protein. 2021 Sep 2
8 34173094 The Effect of Janus Kinase Inhibitors and Phosphodiesterase-4 Inhibitors on Skin and Plasma Cytokine Levels in Patients with Psoriasis. 2021 May 1
9 34226674 Duplication of the IL2RA locus causes excessive IL-2 signaling and may predispose to very early onset colitis. 2021 Sep 1
10 34757416 Treatment of Persistent Erythema Multiforme With Janus Kinase Inhibition and the Role of Interferon Gamma and Interleukin 15 in Its Pathogenesis. 2021 Dec 1 1
11 34868078 Janus Kinase Inhibitors in the Treatment of Vitiligo: A Review. 2021 1
12 31605536 Open-label pilot study of tofacitinib 2% for the treatment of refractory vitiligo. 2020 Apr 1
13 31721311 The Janus Kinase inhibitor tofacitinib impacts human dendritic cell differentiation and favours M1 macrophage development. 2020 Jan 1
14 31751457 The JAK-Inhibitor Tofacitinib Rescues Human Intestinal Epithelial Cells and Colonoids from Cytokine-Induced Barrier Dysfunction. 2020 Feb 11 3
15 32695877 Attenuation of Dupuytren's fibrosis via targeting of the STAT1 modulated IL-13Rα1 response. 2020 Jul 1
16 33031288 Herpes Zoster in rheumatoid arthritis patients receiving tofacitinib, a single center experience from Taiwan. 2020 Oct 9 1
17 30846331 Interferon-γ upregulates Δ42PD1 expression on human monocytes via the PI3K/AKT pathway. 2019 May 1
18 31173242 Effect of platinum‑based chemotherapy on the expression of natural killer group 2 member D ligands, programmed cell death‑1 ligand 1 and HLA class I in non‑small cell lung cancer. 2019 Aug 1
19 31780862 Changes in Serum Cytokines May Predict Therapeutic Efficacy of Tofacitinib in Rheumatoid Arthritis. 2019 1
20 28513593 Jak3 deficiency blocks innate lymphoid cell development. 2018 Jan 1
21 29254929 Inhibition of JAK-STAT Signaling Suppresses Pathogenic Immune Responses in Medium and Large Vessel Vasculitis. 2018 May 1 1
22 30002661 Janus Kinase Inhibitor Baricitinib Modulates Human Innate and Adaptive Immune System. 2018 1
23 28754958 A study on the risk of fungal infection with tofacitinib (CP-690550), a novel oral agent for rheumatoid arthritis. 2017 Jul 28 1
24 29225517 Intestinally-restricted Janus Kinase inhibition: a potential approach to maximize the therapeutic index in inflammatory bowel disease therapy. 2017 1
25 29268845 [Inhibitory effect and mechanism of tofacitinib on the secretion of cytokines by T cells in human peripheral blood]. 2017 Nov 3
26 26689752 Anti-inflammatory effect of topical administration of tofacitinib on corneal inflammation. 2016 Apr 2
27 24213371 Reversal of CD8 T-cell-mediated mucocutaneous graft-versus-host-like disease by the JAK inhibitor tofacitinib. 2014 Apr 1
28 23274966 Comparison of the effect of standard and novel immunosuppressive drugs on CMV-specific T-cell cytokine profiling. 2013 Feb 15 1
29 22147632 The JAK inhibitor tofacitinib regulates synovitis through inhibition of interferon-γ and interleukin-17 production by human CD4+ T cells. 2012 Jun 3
30 22460142 In vitro and in vivo analysis of a JAK inhibitor in rheumatoid arthritis. 2012 Apr 1
31 20697326 CP-690550, a Janus kinase inhibitor, suppresses CD4+ T-cell-mediated acute graft-versus-host disease by inhibiting the interferon-γ pathway. 2010 Oct 27 4
32 19136895 The effect of the JAK inhibitor CP-690,550 on peripheral immune parameters in stable kidney allograft patients. 2009 Jan 15 1