Guanine Nucleotides

Rho/Rac guanine nucleotide exchange factor 2 ; Homo sapiens







29 Article(s)
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1 34229552 RAB7 activity is required for the regulation of mitophagy in oocyte meiosis and oocyte quality control during ovarian aging. 2022 Mar 1
2 34663953 Microtubules tune mechanosensitive cell responses. 2022 Mar 1
3 33126816 Regulation and functions of the RhoA regulatory guanine nucleotide exchange factor GEF-H1. 2021 Sep-Nov 1
4 33762326 The Regulatory Subunit PPP2R2A of PP2A Enhances Th1 and Th17 Differentiation through Activation of the GEF-H1/RhoA/ROCK Signaling Pathway. 2021 Apr 15 1
5 34345888 Phosphorylated cingulin localises GEF-H1 at tight junctions to protect vascular barriers in blood endothelial cells. 2021 Sep 1 1
6 31624147 Large-scale conformational rearrangement of the α5-helix of Gα subunits in complex with the guanine nucleotide exchange factor Ric8A. 2019 Nov 22 1
7 30485813 PKCε Inhibits Neuronal Dendritic Spine Development through Dual Phosphorylation of Ephexin5. 2018 Nov 27 1
8 29106825 Recurrent De Novo Mutations Disturbing the GTP/GDP Binding Pocket of RAB11B Cause Intellectual Disability and a Distinctive Brain Phenotype. 2017 Nov 2 1
9 26759237 RASSF1A Suppresses the Invasion and Metastatic Potential of Human Non-Small Cell Lung Cancer Cells by Inhibiting YAP Activation through the GEF-H1/RhoB Pathway. 2016 Mar 15 1
10 27558716 Nanosecond Dynamics of Gαi1 Bound to Nucleotides or Ric-8A, a Gα Chaperone with GEF Activity. 2016 Aug 23 1
11 25825487 Combined rational design and a high throughput screening platform for identifying chemical inhibitors of a Ras-activating enzyme. 2015 May 15 1
12 26285592 Biochemical effects of mutations in the gene encoding the alpha subunit of eukaryotic initiation factor (eIF) 2B associated with Vanishing White Matter disease. 2015 Aug 19 1
13 22421037 GEFs on the RhoAd to a colossal nucleus. 2012 Mar 13 1
14 22949735 FAM123A binds to microtubules and inhibits the guanine nucleotide exchange factor ARHGEF2 to decrease actomyosin contractility. 2012 Sep 4 1
15 21064165 Modulation of a GEF switch: autoinhibition of the intrinsic guanine nucleotide exchange activity of p115-RhoGEF. 2011 Jan 2
16 21295482 Control of local Rho GTPase crosstalk by Abr. 2011 Feb 22 1
17 21307862 Functional analysis of recently identified mutations in eukaryotic translation initiation factor 2Bɛ (eIF2Bɛ) identified in Chinese patients with vanishing white matter disease. 2011 Apr 1
18 19361519 Kinetic analysis of the guanine nucleotide exchange activity of TRAPP, a multimeric Ypt1p exchange factor. 2009 Jun 5 1
19 18211802 ERK1/2 phosphorylate GEF-H1 to enhance its guanine nucleotide exchange activity toward RhoA. 2008 Mar 28 2
20 18631136 Clues to the mechanism of action of eIF2B, the guanine-nucleotide-exchange factor for translation initiation. 2008 Aug 1
21 17275330 Remedial strategies in structural proteomics: expression, purification, and crystallization of the Vav1/Rac1 complex. 2007 May 1
22 17765544 GEF what? Dock180 and related proteins help Rac to polarize cells in new ways. 2007 Aug 1
23 16472651 Phosphorylation of RhoGDI by p21-activated kinase 1. 2006 1
24 14970201 p21-activated kinase 1 phosphorylates and regulates 14-3-3 binding to GEF-H1, a microtubule-localized Rho exchange factor. 2004 Apr 30 1
25 11158328 New signaling pathways for hormones and cyclic adenosine 3',5'-monophosphate action in endocrine cells. 2001 Feb 1
26 10843989 The role of Mg2+ cofactor in the guanine nucleotide exchange and GTP hydrolysis reactions of Rho family GTP-binding proteins. 2000 Aug 18 2
27 9843686 Nuclear transport factor p10/NTF2 functions as a Ran-GDP dissociation inhibitor (Ran-GDI). 1998 Dec 3 1
28 9857026 Cloning and characterization of GEF-H1, a microtubule-associated guanine nucleotide exchange factor for Rac and Rho GTPases. 1998 Dec 25 1
29 8049218 Phosphorylation of the guanine nucleotide exchange factor and eukaryotic initiation factor 2 by casein kinase II regulates guanine nucleotide binding and GDP/GTP exchange. 1994 Aug 9 2