| 1 |
35522298 | AR cooperates with SMAD4 to maintain skeletal muscle homeostasis. | 2022 Jun |
3 |
| 2 |
32856205 | ClC-2-like Chloride Current Alterations in a Cell Model of Spinal and Bulbar Muscular Atrophy, a Polyglutamine Disease. | 2021 Mar |
4 |
| 3 |
33170804 | Deubiquitinase USP7 contributes to the pathogenicity of spinal and bulbar muscular atrophy. | 2021 Jan 4 |
4 |
| 4 |
33738134 | Selective suppression of polyglutamine-expanded protein by lipid nanoparticle-delivered siRNA targeting CAG expansions in the mouse CNS. | 2021 Jun 4 |
2 |
| 5 |
34417184 | Gene therapy with AR isoform 2 rescues spinal and bulbar muscular atrophy phenotype by modulating AR transcriptional activity. | 2021 Aug |
6 |
| 6 |
32019272 | Polyglutamine-Expanded Androgen Receptor Alteration of Skeletal Muscle Homeostasis and Myonuclear Aggregation Are Affected by Sex, Age and Muscle Metabolism. | 2020 Jan 30 |
8 |
| 7 |
30940675 | DNA methylation inhibitor attenuates polyglutamine-induced neurodegeneration by regulating Hes5. | 2019 May |
2 |
| 8 |
29809168 | Androgen receptor polyglutamine expansion drives age-dependent quality control defects and muscle dysfunction. | 2018 Aug 1 |
4 |
| 9 |
29897452 | Pre-clinical symptoms of SBMA may not be androgen-dependent: implications from two SBMA mouse models. | 2018 Jul 15 |
2 |
| 10 |
30148479 | Systemic Delivery of MicroRNA Using Recombinant Adeno-associated Virus Serotype 9 to Treat Neuromuscular Diseases in Rodents. | 2018 Aug 10 |
1 |
| 11 |
28117338 | Beta-agonist stimulation ameliorates the phenotype of spinal and bulbar muscular atrophy mice and patient-derived myotubes. | 2017 Jan 24 |
3 |
| 12 |
27517091 | Non-Cell-Autonomous Regulation of Retrograde Motoneuronal Axonal Transport in an SBMA Mouse Model. | 2016 Jul-Aug |
3 |
| 13 |
28003546 | Adenylyl cyclase activating polypeptide reduces phosphorylation and toxicity of the polyglutamine-expanded androgen receptor in spinobulbar muscular atrophy. | 2016 Dec 21 |
4 |
| 14 |
25607836 | Fighting polyglutamine disease by wrestling with SUMO. | 2015 Feb |
5 |
| 15 |
25607844 | Disrupting SUMOylation enhances transcriptional function and ameliorates polyglutamine androgen receptor-mediated disease. | 2015 Feb |
5 |
| 16 |
25719894 | Transcriptional profile of muscle following acute induction of symptoms in a mouse model of Kennedy's disease/spinobulbar muscular atrophy. | 2015 |
2 |
| 17 |
25904795 | Distinct Etiological Roles for Myocytes and Motor Neurons in a Mouse Model of Kennedy's Disease/Spinobulbar Muscular Atrophy. | 2015 Apr 22 |
4 |
| 18 |
26308581 | Nemo-like kinase is a novel regulator of spinal and bulbar muscular atrophy. | 2015 Aug 26 |
4 |
| 19 |
26551462 | Overexpression of hepatocyte growth factor in SBMA model mice has an additive effect on combination therapy with castration. | 2015 Dec 25 |
4 |
| 20 |
26673324 | Preventing the Androgen Receptor N/C Interaction Delays Disease Onset in a Mouse Model of SBMA. | 2015 Dec 15 |
4 |
| 21 |
24150846 | Transcriptional activation of TFEB/ZKSCAN3 target genes underlies enhanced autophagy in spinobulbar muscular atrophy. | 2014 Mar 1 |
2 |
| 22 |
24742193 | Antiandrogen flutamide protects male mice from androgen-dependent toxicity in three models of spinal bulbar muscular atrophy. | 2014 Jul |
4 |
| 23 |
24742458 | Muscle expression of mutant androgen receptor accounts for systemic and motor neuron disease phenotypes in spinal and bulbar muscular atrophy. | 2014 Apr 16 |
4 |
| 24 |
24898351 | Endoplasmic reticulum stress in spinal and bulbar muscular atrophy: a potential target for therapy. | 2014 Jul |
1 |
| 25 |
23360996 | Heat shock factor-1 influences pathological lesion distribution of polyglutamine-induced neurodegeneration. | 2013 |
1 |
| 26 |
23363377 | Genistein, a natural product derived from soybeans, ameliorates polyglutamine-mediated motor neuron disease. | 2013 Jul |
2 |
| 27 |
23393146 | Co-induction of the heat shock response ameliorates disease progression in a mouse model of human spinal and bulbar muscular atrophy: implications for therapy. | 2013 Mar |
1 |
| 28 |
23720649 | Mechanisms mediating spinal and bulbar muscular atrophy: investigations into polyglutamine-expanded androgen receptor function and dysfunction. | 2013 |
5 |
| 29 |
24291840 | [MicroRNA in neurodegenerative disorders]. | 2013 |
2 |
| 30 |
22736030 | A polyglutamine expansion disease protein sequesters PTIP to attenuate DNA repair and increase genomic instability. | 2012 Oct 1 |
1 |
| 31 |
22952056 | Insulinlike growth factor (IGF)-1 administration ameliorates disease manifestations in a mouse model of spinal and bulbar muscular atrophy. | 2012 Dec 6 |
1 |
| 32 |
21317158 | Absence of disturbed axonal transport in spinal and bulbar muscular atrophy. | 2011 May 1 |
5 |
| 33 |
21828246 | Androgen receptor polyglutamine repeat length affects receptor activity and C2C12 cell development. | 2011 Oct 20 |
1 |
| 34 |
21921465 | [Molecular-targeted therapy for spinal and bulbar muscular atrophy (SBMA)]. | 2010 Nov |
2 |
| 35 |
19228953 | Polyglutamine-expanded androgen receptor truncation fragments activate a Bax-dependent apoptotic cascade mediated by DP5/Hrk. | 2009 Feb 18 |
7 |
| 36 |
19279159 | Cytoplasmic retention of polyglutamine-expanded androgen receptor ameliorates disease via autophagy in a mouse model of spinal and bulbar muscular atrophy. | 2009 Jun 1 |
4 |
| 37 |
18321505 | Androgen receptor and Kennedy disease/spinal bulbar muscular atrophy. | 2008 May |
1 |
| 38 |
17334372 | ASC-J9 ameliorates spinal and bulbar muscular atrophy phenotype via degradation of androgen receptor. | 2007 Mar |
1 |
| 39 |
17359355 | Pathogenesis and molecular targeted therapy of spinal and bulbar muscular atrophy. | 2007 Apr |
5 |
| 40 |
17494697 | CHIP overexpression reduces mutant androgen receptor protein and ameliorates phenotypes of the spinal and bulbar muscular atrophy transgenic mouse model. | 2007 May 9 |
2 |
| 41 |
18210842 | [Animal models of neurodegenerative diseases on the road to disease-modifying therapy: spinal and bulbar muscular atrophy]. | 2007 Nov |
2 |
| 42 |
16741751 | Modulation of Hsp90 function in neurodegenerative disorders: a molecular-targeted therapy against disease-causing protein. | 2006 Aug |
1 |
| 43 |
16772330 | Loss of endogenous androgen receptor protein accelerates motor neuron degeneration and accentuates androgen insensitivity in a mouse model of X-linked spinal and bulbar muscular atrophy. | 2006 Jul 15 |
1 |
| 44 |
16155577 | 17-AAG, an Hsp90 inhibitor, ameliorates polyglutamine-mediated motor neuron degeneration. | 2005 Oct |
1 |
| 45 |
16260738 | Pharmacological induction of heat-shock proteins alleviates polyglutamine-mediated motor neuron disease. | 2005 Nov 15 |
1 |
| 46 |
15003169 | Androgen receptor YAC transgenic mice recapitulate SBMA motor neuronopathy and implicate VEGF164 in the motor neuron degeneration. | 2004 Mar 4 |
3 |
| 47 |
15102712 | Sodium butyrate ameliorates phenotypic expression in a transgenic mouse model of spinal and bulbar muscular atrophy. | 2004 Jun 1 |
2 |
| 48 |
15133611 | Spinal and bulbar muscular atrophy: ligand-dependent pathogenesis and therapeutic perspectives. | 2004 May |
4 |
| 49 |
15152038 | Castration restores function and neurofilament alterations of aged symptomatic males in a transgenic mouse model of spinal and bulbar muscular atrophy. | 2004 May 19 |
2 |
| 50 |
12657679 | Heat shock protein 70 chaperone overexpression ameliorates phenotypes of the spinal and bulbar muscular atrophy transgenic mouse model by reducing nuclear-localized mutant androgen receptor protein. | 2003 Mar 15 |
4 |