polyglutamine

chaperone ATPase HSP104 ; Saccharomyces cerevisiae S288C







17 Article(s)
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Pub. Year
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1 34424055 Huntingtin Polyglutamine Fragments Are a Substrate for Hsp104 in Saccharomyces cerevisiae. 2021 Oct 26 1
2 33175887 Hsp104-dependent ability to assimilate mannitol and sorbitol conferred by a truncated Cyc8 with a C-terminal polyglutamine in Saccharomyces cerevisiae. 2020 1
3 30595457 Structure of Calcarisporiella thermophila Hsp104 Disaggregase that Antagonizes Diverse Proteotoxic Misfolding Events. 2019 Mar 5 1
4 24039611 Hsp104 suppresses polyglutamine-induced degeneration post onset in a drosophila MJD/SCA3 model. 2013 2
5 22723742 Small heat shock proteins potentiate amyloid dissolution by protein disaggregases from yeast and humans. 2012 1
6 21969373 Ordered assembly of heat shock proteins, Hsp26, Hsp70, Hsp90, and Hsp104, on expanded polyglutamine fragments revealed by chemical probes. 2011 Nov 25 3
7 19768774 Structure and function of the molecular chaperone Hsp104 from yeast. 2010 Mar 3
8 19995551 Hsp104 is essential for the selective degradation in yeast of polyglutamine expanded ataxin-1 but not most misfolded proteins generally. 2010 Jan 1 1
9 18381282 Appearance and propagation of polyglutamine-based amyloids in yeast: tyrosine residues enable polymer fragmentation. 2008 May 30 1
10 16973603 Critical role of the proline-rich region in Huntingtin for aggregation and cytotoxicity in yeast. 2006 Nov 24 1
11 15845535 A chaperone pathway in protein disaggregation. Hsp26 alters the nature of protein aggregates to facilitate reactivation by Hsp104. 2005 Jun 24 1
12 16204350 Overexpression of yeast hsp104 reduces polyglutamine aggregation and prolongs survival of a transgenic mouse model of Huntington's disease. 2005 Nov 15 1
13 15298677 The role of pre-existing aggregates in Hsp104-dependent polyglutamine aggregate formation and epigenetic change of yeast prions. 2004 Aug 4
14 12058016 Huntington toxicity in yeast model depends on polyglutamine aggregation mediated by a prion-like protein Rnq1. 2002 Jun 10 1
15 12161426 Circumvention of chaperone requirement for aggregate formation of a short polyglutamine tract by the co-expression of a long polyglutamine tract. 2002 Oct 4 1
16 11683917 Initial process of polyglutamine aggregate formation in vivo. 2001 Oct 3
17 10811890 Polyglutamine aggregates alter protein folding homeostasis in Caenorhabditis elegans. 2000 May 23 1