| 1 |
34417466 | The antidepressant drug vilazodone is an allosteric inhibitor of the serotonin transporter. | 2021 Aug 20 |
1 |
| 2 |
27089947 | Genetically encoded photocrosslinkers locate the high-affinity binding site of antidepressant drugs in the human serotonin transporter. | 2016 Apr 19 |
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| 3 |
23385211 | Basic N-interlinked imipramines show apoptotic activity against malignant cells including Burkitt's lymphoma. | 2013 Mar 1 |
3 |
| 4 |
23706649 | Thermostabilisation of the serotonin transporter in a cocaine-bound conformation. | 2013 Jun 26 |
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| 5 |
21129485 | Functional expression of milligram quantities of the synthetic human serotonin transporter gene in a tetracycline-inducible HEK293 cell line. | 2011 Apr |
1 |
| 6 |
21853482 | Synthesis of 3,7-disubstituted imipramines by palladium-catalysed amination/cyclisation and evaluation of their inhibition of monoamine transporters. | 2011 Sep 12 |
4 |
| 7 |
19892699 | Mutational mapping and modeling of the binding site for (S)-citalopram in the human serotonin transporter. | 2010 Jan 15 |
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| 8 |
19948720 | Binding and orientation of tricyclic antidepressants within the central substrate site of the human serotonin transporter. | 2010 Mar 12 |
1 |
| 9 |
20073575 | Characterization of monoamine oxidases in mesenchymal stem cells: role in hydrogen peroxide generation and serotonin-dependent apoptosis. | 2010 Oct |
1 |
| 10 |
20829432 | The high-affinity binding site for tricyclic antidepressants resides in the outer vestibule of the serotonin transporter. | 2010 Dec |
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| 11 |
19213730 | Location of the antidepressant binding site in the serotonin transporter: importance of Ser-438 in recognition of citalopram and tricyclic antidepressants. | 2009 Apr 10 |
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| 12 |
19641126 | Fluoxetine (Prozac) binding to serotonin transporter is modulated by chloride and conformational changes. | 2009 Jul 29 |
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| 13 |
18801947 | Antidepressants targeting the serotonin reuptake transporter act via a competitive mechanism. | 2008 Dec |
2 |
| 14 |
17499240 | Allosteric effects of R- and S-citalopram on the human 5-HT transporter: evidence for distinct high- and low-affinity binding sites. | 2007 Jul 12 |
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| 15 |
15625090 | Selective serotonin reuptake inhibitors induce spontaneous interneuronal activity in the leech nervous system. | 2005 May |
1 |
| 16 |
16112691 | Serotonin transporter mutations associated with obsessive-compulsive disorder and phosphorylation alter binding affinity for inhibitors. | 2005 Nov |
1 |
| 17 |
15023476 | Serotonergic platelet markers of suicidal behavior--do they really exist? | 2004 Apr |
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| 18 |
12849931 | Serotonin transporter and MAO-B levels in monoamine nuclei of the human brainstem are normal in major depression. | 2003 Sep-Oct |
1 |
| 19 |
11513817 | Clinical and neurochemical effect of acute tryptophan depletion in unaffected relatives of patients with bipolar affective disorder. | 2001 Aug 1 |
1 |
| 20 |
11677251 | Species-scanning mutagenesis of the serotonin transporter reveals residues essential in selective, high-affinity recognition of antidepressants. | 2001 Oct |
1 |
| 21 |
11746710 | Non-amines, drugs without an amine nitrogen, potently block serotonin transport: novel antidepressant candidates? | 2001 Dec 1 |
1 |
| 22 |
10869387 | Transporter-mediated release: a superfusion study on human embryonic kidney cells stably expressing the human serotonin transporter. | 2000 Jun |
1 |
| 23 |
10624553 | Decreased serotonin transporter binding in unaffected relatives of manic depressive patients. | 1999 Dec 15 |
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| 24 |
9832351 | Active [3H]-dopamine uptake displayed by native lymphocyte suspensions is mainly due to contaminating platelets. | 1998 Sep |
1 |
| 25 |
8863842 | Identification of a single amino acid, phenylalanine 586, that is responsible for high affinity interactions of tricyclic antidepressants with the human serotonin transporter. | 1996 Oct |
1 |
| 26 |
8923121 | Two actions are better than one: avoiding self-inhibition of serotonergic neurones enhances the effects of serotonin uptake inhibitors. | 1996 Sep |
1 |
| 27 |
7478203 | Specific binding of [3H]imipramine indicates the presence of a specific serotonin transport system on endothelial cells of porcine brain. | 1995 Jul 14 |
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| 28 |
7711157 | Primary structure of the serotonin transporter in unipolar depression and bipolar disorder. | 1995 Feb 15 |
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| 29 |
7758754 | Dithiothreithol promotes a higher affinity state of the serotonin transporter for the tricyclic antidepressant, imipramine. | 1995 Feb |
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| 30 |
7928004 | Expression of a high-affinity serotonin transporter in human lymphocytes. | 1994 Jul |
1 |
| 31 |
8016192 | Active [3H]-dopamine uptake by human lymphocytes: correlates with serotonin transporter activity. | 1994 May |
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| 32 |
8050484 | Kinase inhibitors compete with imipramine for binding and inhibition of serotonin transport. | 1994 Apr 15 |
1 |
| 33 |
8218295 | Sodium- and chloride-dependent, cocaine-sensitive, high-affinity binding of nisoxetine to the human placental norepinephrine transporter. | 1993 Nov 16 |
1 |
| 34 |
2811859 | 2-Iodoimipramine, a novel ligand for the serotonin transporter. | 1989 Oct |
1 |
| 35 |
2898799 | Effects of antidepressants on monoamine transporters. | 1988 |
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| 36 |
2947974 | Temperature dependence of drug interaction with the platelet 5-hydroxytryptamine transporter: a clue to the imipramine selectivity paradox. | 1987 Feb |
7 |
| 37 |
3816412 | Antidepressant-binding sites in brain and platelets. | 1986 |
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| 38 |
3871227 | Tryptamine, a substrate for the serotonin transporter in human platelets, modifies the dissociation kinetics of [3H]imipramine binding: possible allosteric interaction. | 1985 Feb |
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| 39 |
6835029 | [3H]2-Nitroimipramine: a selective "slowly-dissociating" probe of the imipramine binding site ("serotonin transporter") in platelets and brain. | 1983 Feb 7 |
2 |
| 40 |
7056713 | Coupling of transmembrane proton gradients to platelet serotonin transport. | 1982 Feb 10 |
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