Paroxetine

solute carrier family 6 member 4 ; Homo sapiens







105 Article(s)
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1 34958348 Differential Potency of Venlafaxine, Paroxetine, and Atomoxetine to Inhibit Serotonin and Norepinephrine Reuptake in Patients With Major Depressive Disorder. 2022 Apr 19 2
2 35053371 Sodium Binding Stabilizes the Outward-Open State of SERT by Limiting Bundle Domain Motions. 2022 Jan 12 2
3 35090865 Multiple Transport Mechanisms Involved in the Intestinal Absorption of Metformin: Impact on the Nonlinear Absorption Kinetics. 2022 May 1
4 34867196 A Novel Biotinylated Homotryptamine Derivative for Quantum Dot Imaging of Serotonin Transporter in Live Cells. 2021 1
5 31634334 Modification of the association between paroxetine serum concentration and SERT-occupancy by ABCB1 (P-glycoprotein) polymorphisms in major depressive disorder. 2020 Feb 2
6 32618269 Chemical and structural investigation of the paroxetine-human serotonin transporter complex. 2020 Jul 3 3
7 30391505 Computation-guided analysis of paroxetine binding to hSERT reveals functionally important structural elements and dynamics. 2019 Dec 15 3
8 31424193 A Novel Bromine-Containing Paroxetine Analogue Provides Mechanistic Clues for Binding Ambiguity at the Central Primary Binding Site of the Serotonin Transporter. 2019 Sep 18 4
9 29379174 Structural basis for recognition of diverse antidepressants by the human serotonin transporter. 2018 Feb 1
10 28910072 Mapping the Binding Site for Escitalopram and Paroxetine in the Human Serotonin Transporter Using Genetically Encoded Photo-Cross-Linkers. 2017 Oct 20 1
11 27049939 X-ray structures and mechanism of the human serotonin transporter. 2016 Apr 21 1
12 27236282 One-step preparation of [(18)F]FPBM for PET imaging of serotonin transporter (SERT) in the brain. 2016 Aug 1
13 27244236 Decreased sensitivity to paroxetine-induced inhibition of peripheral blood mononuclear cell growth in depressed and antidepressant treatment-resistant patients. 2016 May 31 1
14 27738376 Paroxetine-The Antidepressant from Hell? Probably Not, But Caution Required. 2016 Mar 1 1
15 26253622 Differentiated effects of the multimodal antidepressant vortioxetine on sleep architecture: Part 1, a pharmacokinetic/pharmacodynamic comparison with paroxetine in healthy men. 2015 Oct 1
16 26695939 Thermostabilization of the Human Serotonin Transporter in an Antidepressant-Bound Conformation. 2015 3
17 24406081 Occupancy of serotonin transporters in the amygdala by paroxetine in association with attenuation of left amygdala activation by negative faces in major depressive disorder. 2014 Feb 28 2
18 24578810 Serotonin Transporter Promoter Region (5-HTTLPR) Polymorphism Is Not Associated With Paroxetine-Induced Ejaculation Delay in Dutch Men With Lifelong Premature Ejaculation. 2014 Feb 2
19 24673477 Hybrid molecules inhibiting myeloperoxidase activity and serotonin reuptake: a possible new approach of major depressive disorders with inflammatory syndrome. 2014 Aug 1
20 24858363 The influence of 5-HTTLPR genotype on the association between the plasma concentration and therapeutic effect of paroxetine in patients with major depressive disorder. 2014 2
21 25258536 Factors affecting discontinuation of initial treatment with paroxetine in panic disorder and major depressive disorder. 2014 2
22 23288236 5-HTTLPR rs25531A > G differentially influence paroxetine and fluvoxamine antidepressant efficacy: a randomized, controlled trial. 2013 Feb 1
23 23706649 Thermostabilisation of the serotonin transporter in a cocaine-bound conformation. 2013 Jun 26 1
24 24138674 The expression of platelet serotonin transporter (SERT) in human obesity. 2013 Oct 18 2
25 22774398 Modulation of the platelet serotonin transporter by thermal balneotherapy: a study in healthy subjects. 2012 May 1
26 21272963 Synthesis, molecular docking and binding studies of selective serotonin transporter inhibitors. 2011 Mar 1
27 21970724 A fluorescence displacement assay for antidepressant drug discovery based on ligand-conjugated quantum dots. 2011 Nov 9 4
28 20006597 Antagonists and substrates differentially regulate serotonin transporter cell surface expression in serotonergic neurons. 2010 Mar 10 1
29 20075642 Effects of the serotonin 1A, 2A, 2C, 3A, and 3B and serotonin transporter gene polymorphisms on the occurrence of paroxetine discontinuation syndrome. 2010 Feb 1
30 20207008 Platelet serotonin transporter function after short-term paroxetine treatment in patients with panic disorder. 2010 Apr 30 1
31 18563559 Binding of paroxetine to the serotonin transporter in membranes from different cells, subcellular fractions and species. 2009 Feb 3
32 18830236 Evidence why paroxetine dose escalation is not effective in major depressive disorder: a randomized controlled trial with assessment of serotonin transporter occupancy. 2009 Mar 2
33 19606452 Rapid response to paroxetine is associated with plasma paroxetine levels at 4 but not 8 weeks of treatment, and is independent of serotonin transporter promoter polymorphism in Japanese depressed patients. 2009 Aug 1
34 19895766 Drinking histories in alcohol-use-disordered youth: preliminary findings on relationships to platelet serotonin transporter expression with genotypes of the serotonin transporter. 2009 Nov 1
35 17853254 Association study of paroxetine therapeutic response with SERT gene polymorphisms in patients with major depressive disorder. 2008 1
36 18279474 Serotonin transporter polymorphism and bleeding time during SSRI therapy. 2008 May 1
37 18330458 Serotonin transporter genotype interacts with paroxetine plasma levels to influence depression treatment response in geriatric patients. 2008 Mar 1
38 18418363 Estimates of serotonin and norepinephrine transporter inhibition in depressed patients treated with paroxetine or venlafaxine. 2008 Dec 4
39 18427983 Epileptic seizures but not pseudoseizures are associated with decreased density of the serotonin transporter in blood platelet membranes. 2008 Nov 1
40 18451636 Decreased density of the platelet serotonin transporter in pathological gamblers. 2008 2
41 18502014 Sequential serotonin and noradrenalin associated processes involved in postpartum blues. 2008 Jul 1 1
42 18552871 Prediction of clinical response based on pharmacokinetic/pharmacodynamic models of 5-hydroxytryptamine reuptake inhibitors in mice. 2008 Sep 1
43 18788029 Catatonic features in major depression relieved by electroconvulsive treatment: parallel evaluation of the status of platelet serotonin transporter. 2008 Oct 1
44 18983505 Effect of the selective serotonin reuptake inhibitor paroxetine on platelet function is modified by a SLC6A4 serotonin transporter polymorphism. 2008 Dec 2
45 19936040 Targeting the human serotonin transporter (hSERT) with quantum dots. 2008 Feb 22 1
46 17499240 Allosteric effects of R- and S-citalopram on the human 5-HT transporter: evidence for distinct high- and low-affinity binding sites. 2007 Jul 12 2
47 17709099 Selective serotonin reuptake inhibitors--a new modality for the treatment of lymphoma/leukaemia? 2007 Nov 1 1
48 17890444 Pharmacological interaction between 3,4-methylenedioxymethamphetamine (ecstasy) and paroxetine: pharmacological effects and pharmacokinetics. 2007 Dec 1
49 17910821 3-[(Aryl)(4-fluorobenzyloxy)methyl]piperidine derivatives: high-affinity ligands for the serotonin transporter. 2007 Oct 1
50 16790074 Alteration of serotonin transporter density and activity in fibromyalgia. 2006 1