| 1 |
34784956 | Focal adhesion kinase inhibitor TAE226 combined with Sorafenib slows down hepatocellular carcinoma by multiple epigenetic effects. | 2021 Nov 16 |
3 |
| 2 |
31215459 | Pharmacological profiling of a dual FAK/IGF-1R kinase inhibitor TAE226 in cellular and in vivo tumor models. | 2019 Jun 18 |
3 |
| 3 |
29090460 | FAK inhibitors induce cell multinucleation and dramatically increase pro-tumoral cytokine expression in RAW 264.7 macrophages. | 2017 Dec |
2 |
| 4 |
26090892 | TAE226, a Bis-Anilino Pyrimidine Compound, Inhibits the EGFR-Mutant Kinase Including T790M Mutant to Show Anti-Tumor Effect on EGFR-Mutant Non-Small Cell Lung Cancer Cells. | 2015 |
2 |
| 5 |
24860788 | Integrin VLA-5 and FAK are Good Targets to Improve Treatment Response in the Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia. | 2014 |
1 |
| 6 |
24915008 | Laminin α2-mediated focal adhesion kinase activation triggers Alport glomerular pathogenesis. | 2014 |
1 |
| 7 |
23642017 | Antifibrotic effects of focal adhesion kinase inhibitor in bleomycin-induced pulmonary fibrosis in mice. | 2013 Oct |
2 |
| 8 |
24036212 | Activation of integrin β1-focal adhesion kinase-RasGTP pathway plays a critical role in TGF beta1-induced podocyte injury. | 2013 Dec |
1 |
| 9 |
22705303 | Oral administration of FAK inhibitor TAE226 inhibits the progression of peritoneal dissemination of colorectal cancer. | 2012 Jul 13 |
4 |
| 10 |
21347357 | G(12/13) signaling pathways substitute for integrin αIIbβ3-signaling for thromboxane generation in platelets. | 2011 Feb 10 |
1 |
| 11 |
19139121 | Inhibition of focal adhesion kinase as a potential therapeutic strategy for imatinib-resistant gastrointestinal stromal tumor. | 2009 Jan |
1 |
| 12 |
19030106 | Crystal structures of the FAK kinase in complex with TAE226 and related bis-anilino pyrimidine inhibitors reveal a helical DFG conformation. | 2008 |
1 |