Carnitine

solute carrier family 22 member 5 ; Homo sapiens







136 Article(s)
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1 35622436 Acylcarnitines and Genetic Variation in Fat Oxidation Genes in HIV-infected, Antiretroviral-treated Children With and Without Myopathy. 2022 May 25 2
2 32654140 Glioma cells survival depends both on fatty acid oxidation and on functional carnitine transport by SLC22A5. 2021 Mar 6
3 33181153 Newborn screening for primary carnitine deficiency in Quanzhou, China. 2021 Jan 2
4 33334877 Cholesterol stimulates the cellular uptake of L-carnitine by the carnitine/organic cation transporter novel 2 (OCTN2). 2021 Jan-Jun 10
5 34249102 Newborn Screening and Genetic Analysis Identify Six Novel Genetic Variants for Primary Carnitine Deficiency in Ningbo Area, China. 2021 2
6 34478916 Organic cation transporters (OCTs/OCTNs) in human primary alveolar epithelial cells. 2021 Oct 22 1
7 34603016 The Role of the Carnitine/Organic Cation Transporter Novel 2 in the Clinical Outcome of Patients With Locally Advanced Esophageal Carcinoma Treated With Oxaliplatin. 2021 1
8 34824054 Urinary metabotype of severe asthma evidences decreased carnitine metabolism independent of oral corticosteroid treatment in the U-BIOPRED study. 2021 Nov 25 2
9 31864849 Carnitine uptake defect due to a 5'UTR mutation in a pedigree with false positives and false negatives on Newborn screening. 2020 Mar 1
10 31913724 OCTN2-targeted nanoparticles for oral delivery of paclitaxel: differential impact of the polyethylene glycol linker size on drug delivery in vitro, in situ, and in vivo. 2020 Dec 2
11 32027707 Functional analysis of OCTN2 and ATB0,+ in normal human airway epithelial cells. 2020 6
12 32256846 Intestinal OCTN2- and MCT1-targeted drug delivery to improve oral bioavailability. 2020 Mar 1
13 32306775 l-Carnitine conjugated chitosan-stearic acid polymeric micelles for improving the oral bioavailability of paclitaxel. 2020 Dec 4
14 32620667 Sorafenib Might Induce Sarcopenia in Patients With Hepatocellular Carcinoma by Inhibiting Carnitine Absorption. 2020 Jul 1
15 33268576 Biochemical and genetic characteristics of 40 neonates with carnitine deficiency. 2020 Oct 28 2
16 30523710 OCTN: A Small Transporter Subfamily with Great Relevance to Human Pathophysiology, Drug Discovery, and Diagnostics. 2019 Feb 2
17 30670496 L-Carnitine-Mediated Tumor Cell Protection and Poor Patient Survival Associated with OCTN2 Overexpression in Glioblastoma Multiforme. 2019 May 1 4
18 30735677 The inhibitory effect of antiretroviral drugs on the L-carnitine uptake in human placenta. 2019 Apr 1 6
19 30858625 SLC22A5 polymorphism associated with risk of extra-articular manifestations in rheumatoid arthritis patients. 2019 2
20 30863740 Biochemical, Molecular, and Clinical Characterization of Patients With Primary Carnitine Deficiency via Large-Scale Newborn Screening in Xuzhou Area. 2019 3
21 31187905 A mutation creating an upstream translation initiation codon in SLC22A5 5'UTR is a frequent cause of primary carnitine deficiency. 2019 Oct 1
22 31200524 First Case Report of Primary Carnitine Deficiency Manifested as Intellectual Disability and Autism Spectrum Disorder. 2019 Jun 13 2
23 31364285 Molecular investigation in Chinese patients with primary carnitine deficiency. 2019 Sep 3
24 31394757 OCTN2-Mediated Acetyl-l-Carnitine Transport in Human Pulmonary Epithelial Cells In Vitro. 2019 Aug 7 1
25 31500110 Carnitine Inborn Errors of Metabolism. 2019 Sep 6 1
26 31861504 SLC22A5 (OCTN2) Carnitine Transporter-Indispensable for Cell Metabolism, a Jekyll and Hyde of Human Cancer. 2019 Dec 19 7
27 28974108 L-Carnitine-conjugated nanoparticles to promote permeation across blood-brain barrier and to target glioma cells for drug delivery via the novel organic cation/carnitine transporter OCTN2. 2018 Dec 4
28 29614331 Carnitine levels and mutations in the SLC22A5 gene in Faroes patients with Parkinson's disease. 2018 May 14 1
29 30016594 Recent advances in drug delivery via the organic cation/carnitine transporter 2 (OCTN2/SLC22A5). 2018 Aug 3
30 27581592 Primary Carnitine Deficiency - A Rare Treatable Cause of Cardiomyopathy and Massive Hepatomegaly. 2017 Jan 2
31 27733576 Human macrophage differentiation induces OCTN2-mediated L-carnitine transport through stimulation of mTOR-STAT3 axis. 2017 Mar 2
32 28234466 Combination of l-Carnitine with Lipophilic Linkage-Donating Gemcitabine Derivatives as Intestinal Novel Organic Cation Transporter 2-Targeting Oral Prodrugs. 2017 Mar 23 1
33 28295041 Exome sequencing identifies primary carnitine deficiency in a family with cardiomyopathy and sudden death. 2017 Jun 1
34 28365301 Species specificity profiling of rat and human organic cation/carnitine transporter Slc22a5/SLC22A5 (Octn2/OCTN2). 2017 Jun 3
35 28711408 Biochemical characteristics of newborns with carnitine transporter defect identified by newborn screening in California. 2017 Nov 1
36 28911246 Dual targeting of l-carnitine-conjugated nanoparticles to OCTN2 and ATB0,+ to deliver chemotherapeutic agents for colon cancer therapy. 2017 Nov 3
37 29132460 [Genetic diagnosis of 10 neonates with primary carnitine deficiency]. 2017 Nov 1
38 26607009 Functional activity of L-carnitine transporters in human airway epithelial cells. 2016 Feb 6
39 26828774 Carnitine transport and fatty acid oxidation. 2016 Oct 5
40 26850121 Pharmacological effects of meldonium: Biochemical mechanisms and biomarkers of cardiometabolic activity. 2016 Nov 2
41 26994919 Wide tolerance to amino acids substitutions in the OCTN1 ergothioneine transporter. 2016 Jun 4
42 27931018 Primary Carnitine Deficiency and Newborn Screening for Disorders of the Carnitine Cycle. 2016 2
43 25269560 Strategies for skeletal muscle targeting in drug discovery. 2015 1
44 25827849 Multiple acyl-CoA dehydrogenation deficiency as decreased acyl-carnitine profile in serum. 2015 Jun 1
45 25857234 Memantine transport by a proton-coupled organic cation antiporter in hCMEC/D3 cells, an in vitro human blood-brain barrier model. 2015 Apr 1
46 26043725 Acetylcarnitine potentiates the anticarcinogenic effects of butyrate on SW480 colon cancer cells. 2015 Aug 1
47 26075114 Identification of SLC22A5 Gene Mutation in a Family with Carnitine Uptake Defect. 2015 1
48 23379544 Primary carnitine deficiency: novel mutations and insights into the cardiac phenotype. 2014 Feb 2
49 23877104 Functional expression of organic cation/carnitine transporter 2 (OCTN2/SLC22A5) in human brain capillary endothelial cell line hCMEC/D3, a human blood-brain barrier model. 2014 3
50 25132046 Analysis of genetic mutations in Chinese patients with systemic primary carnitine deficiency. 2014 Oct 1