Staurosporine

protein kinase C alpha ; Homo sapiens







52 Article(s)
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1 33986607 Activation of GSK3 Prevents Termination of TNF-Induced Signaling. 2021 2
2 32777211 The role of PKC in CXCL8 and CXCL10 directed prostate, breast and leukemic cancer cell migration. 2020 Nov 5 1
3 30776542 PMA-triggered PKCε activity enhances Nrf2-mediated antiviral response on fish rhabdovirus infection. 2019 Apr 1
4 30618318 Low-dose staurosporine selectively reverses BCR-ABL-independent IM resistance through PKC-α-mediated G2/M phase arrest in chronic myeloid leukaemia. 2018 3
5 26398575 Protein kinase Cα-mediated cytotoxic activity of ineupatorolide B from Inula cappa DC. in HeLa cells. 2015 Nov 1
6 24682423 Isoenzyme-specific regulation of cardiac Kv1.5/Kvβ1.2 ion channel complex by protein kinase C: central role of PKCβII. 2014 May 1
7 19878671 Angiotensin II inhibits activity of human organic anion transporter 3 through activation of protein kinase Calpha: accelerating endocytosis of the transporter. 2010 Feb 10 2
8 19895572 Conventional protein kinase C plays a critical role in negative regulation of CD98-induced homotypic aggregation. 2010 Jan 2
9 19088254 Regulation of human organic anion transporter 1 by ANG II: involvement of protein kinase Calpha. 2009 Feb 1
10 19500428 Effect of staurosporine on the mobility and invasiveness of lung adenocarcinoma A549 cells: an in vitro study. 2009 Jun 8 3
11 17007817 Polycystin-1 promotes PKCalpha-mediated NF-kappaB activation in kidney cells. 2006 Nov 17 1
12 17013757 12-o-Tetradecanoylphorbol 13-acetate prevents baicalein-induced apoptosis via activation of protein kinase C and JNKs in human leukemia cells. 2006 Nov 2
13 16117614 Glycoprotein isolated from Solanum nigrum L. kills HT-29 cells through apoptosis. 2005 Summer 2
14 16225760 Effect of protein kinase C alpha, caspase-3, and survivin on apoptosis of oral cancer cells induced by staurosporine. 2005 Nov 6
15 14522134 Protein kinase C (PKC) isotype profile in eosinophils from ponies with sweet itch and role in histamine-induced eosinophil activation. 2003 Nov 15 1
16 11751911 Interferon-gamma-induced epithelial ICAM-1 expression and monocyte adhesion. Involvement of protein kinase C-dependent c-Src tyrosine kinase activation pathway. 2002 Mar 1 1
17 11994256 Protection of myocytes from hypoxia-reoxygenation injury by nitric oxide is mediated by modulation of transforming growth factor-beta1. 2002 May 7 1
18 11997388 Interplay between calcium, diacylglycerol, and phosphorylation in the spatial and temporal regulation of PKCalpha-GFP. 2002 Aug 9 4
19 12083800 Translocation of the classic protein kinase C isoforms in porcine oocytes: implications of protein kinase C involvement in the regulation of nuclear activity and cortical granule exocytosis. 2002 Jul 15 2
20 12176659 Activation of angiotensin II type I receptor promotes protein kinase C translocation and cell proliferation in human cultured breast epithelial cells. 2002 Aug 1
21 12190943 Dual role of protein kinase C on mitogen-activated protein kinase activation and human keratinocyte proliferation. 2002 Aug 1
22 11158204 Regulation of Bcl2 phosphorylation and potential significance for leukemic cell chemoresistance. 2001 2
23 11182772 Na+/K+ATPase activity inhibition and isoform-specific translocation of protein kinase C following angiotensin II administration in isolated eel enterocytes. 2001 Feb 3
24 11483407 Tumor necrosis factor alpha-induced activation of downstream NF-kappaB site of the promoter mediates epithelial ICAM-1 expression and monocyte adhesion. Involvement of PKCalpha, tyrosine kinase, and IKK2, but not MAPKs, pathway. 2001 Aug 1
25 10627456 Protein kinase C-alpha isoform is involved in erythropoietin-induced erythroid differentiation of CD34(+) progenitor cells from human bone marrow. 2000 Jan 15 1
26 11093788 Protein kinase calpha but not p44/42 mitogen-activated protein kinase, p38, or c-Jun NH(2)-terminal kinase is required for intercellular adhesion molecule-1 expression mediated by interleukin-1beta: involvement of sequential activation of tyrosine kinase, nuclear factor-kappaB-inducing kinase, and IkappaB kinase 2. 2000 Dec 1
27 10523856 Phorbol ester induced MDR1 expression in K562 cells occurs independently of mitogen-activated protein kinase signaling pathways. 1999 Oct 14 1
28 9593858 Role of protein kinase C alpha in endothelin-1 stimulation of cytosolic phospholipase A2 and arachidonic acid release in cultured cat iris sphincter smooth muscle cells. 1998 May 20 2
29 9734941 Endothelial-cell permeability and protein kinase C in pre-eclampsia. 1998 Mar 28 1
30 9769475 Cytoskeletal reorganization induced by retinoic acid treatment of human endometrial adenocarcinoma (RL95-2) cells is correlated with alterations in protein kinase C-alpha. 1998 1
31 9150270 Inhibitors of actin polymerization and calmodulin binding enhance protein kinase C-induced translocation of MARCKS in C6 glioma cells. 1997 Apr 24 2
32 9203625 Antisense oligonucleotides targeting human protein kinase C-alpha inhibit phorbol ester-induced reduction of bradykinin-evoked calcium mobilization in A549 cells. 1997 Feb 1
33 9346296 Characteristics of protein-kinase-C- and ADP-ribosylation-factor-stimulated phospholipase D activities in human embryonic kidney cells. 1997 Sep 1 1
34 9361188 Cyclic strain stimulates isoform-specific PKC activation and translocation in cultured human keratinocytes. 1997 Dec 1 1
35 9392422 Phorbol ester-induced low density lipoprotein receptor gene expression in HepG2 cells involves protein kinase C-mediated p42/44 MAP kinase activation. 1997 Nov 1
36 8617370 Regulation of type V adenylyl cyclase by PMA-sensitive and -insensitive protein kinase C isoenzymes in intact cells. 1996 Apr 22 1
37 8626805 Regulation of phospholipase D by protein kinase C is synergistic with ADP-ribosylation factor and independent of protein kinase activity. 1996 Feb 23 1
38 8943287 Transcriptional regulation of insulin receptor substrate 1 by protein kinase C. 1996 Dec 13 1
39 7547506 Rapid activation and down-regulation of protein kinase C alpha in 12-O-Tetradecanoylphorbol-13-acetate-induced differentiation of human rhabdomyosarcoma cells. 1995 Jul 1
40 7710931 Comparison of ability of protein kinase C inhibitors to arrest cell growth and to alter cellular protein kinase C localisation. 1995 Apr 3
41 8554927 Translocation of protein kinase C isoenzymes by elevated extracellular Ca2+ concentration in cells from a human giant cell tumor of bone. 1995 Aug 1
42 7525931 Induction of 12-lipoxygenase expression by epidermal growth factor is mediated by protein kinase C in A431 cells. 1994 Oct 1
43 7923629 Dissociation of vasoconstrictor-stimulated basic fibroblast growth factor expression from hypertrophic growth in cultured vascular smooth muscle cells. Relevant roles of protein kinase C. 1994 Nov 1
44 7943245 1,25(OH)2 vitamin D3 activates PKC-alpha in Caco-2 cells: a mechanism to limit secosteroid-induced rise in [Ca2+]i. 1994 Sep 1
45 8022414 Differential inhibition of protein kinase C isozymes by UCN-01, a staurosporine analogue. 1994 Jun 1
46 8224186 Conventional protein kinase C isoforms are not essential for cellular proliferation of a T cell lymphoma line. 1993 Nov 1 1
47 8477816 Protein kinase C inhibitors potentiate angiotensin II-induced phosphoinositide hydrolysis and intracellular Ca2+ mobilization in renal mesangial cells. 1993 Mar 15 1
48 1444457 Differentiation of HL-60 cells by phorbol ester is correlated with up-regulation of protein kinase C-alpha. 1992 Dec 1
49 1577171 Development and characterization of a protein kinase C beta-isozyme-deficient T-cell line. 1992 Apr 27 1
50 1616823 Inducible overexpression of human protein kinase C alpha in NIH 3T3 fibroblasts results in growth abnormalities. 1992 Mar 1