| 1 |
34363018 | Lactate promotes macrophage HMGB1 lactylation, acetylation, and exosomal release in polymicrobial sepsis. | 2022 Jan |
2 |
| 2 |
34472101 | l-lactic acidosis confers insensitivity to PKC inhibitors by competing for uptake via monocarboxylate transporters. | 2022 Jan |
1 |
| 3 |
34486916 | Effects of lactate in immunosuppression and inflammation: Progress and prospects. | 2022 |
2 |
| 4 |
35182679 | Transcriptomic and functional studies reveal miR-431-5p as a tumour suppressor in pancreatic ductal adenocarcinoma cells. | 2022 May 15 |
2 |
| 5 |
35204157 | The Crosstalk between GPR81/IGFBP6 Promotes Breast Cancer Progression by Modulating Lactate Metabolism and Oxidative Stress. | 2022 Jan 29 |
5 |
| 6 |
35240875 | Activation of lactate receptor HCAR1 down-modulates neuronal activity in rodent and human brain tissue. | 2022 Mar 3 |
2 |
| 7 |
35323413 | Evaluation of Hydroxycarboxylic Acid Receptor 1 (HCAR1) as a Building Block for Genetically Encoded Extracellular Lactate Biosensors. | 2022 Feb 25 |
10 |
| 8 |
35428832 | The lactate sensor GPR81 regulates glycolysis and tumor growth of breast cancer. | 2022 Apr 15 |
6 |
| 9 |
35454162 | Comment on Chen et al. Dual Blockade of Lactate/GPR81 and PD-1/PD-L1 Pathways Enhances the Anti-Tumor Effects of Metformin. Biomolecules 2021, 11, 1373. | 2022 Apr 13 |
1 |
| 10 |
35574309 | Lactate Induces the Expressions of MCT1 and HCAR1 to Promote Tumor Growth and Progression in Glioblastoma. | 2022 |
6 |
| 11 |
33293196 | Corrigendum to "A lactate-induced Snail/STAT3 pathway drives GPR81 expression in lung cancer cells" [Biochim. Biophys. Acta (BBA) - Mol. Basis Dis. 1866 (2020) Article 165576]. | 2021 Mar 1 |
1 |
| 12 |
34093243 | Hydroxycarboxylic Acid Receptor 1 and Neuroprotection in a Mouse Model of Cerebral Ischemia-Reperfusion. | 2021 |
1 |
| 13 |
34572586 | Dual Blockade of Lactate/GPR81 and PD-1/PD-L1 Pathways Enhances the Anti-Tumor Effects of Metformin. | 2021 Sep 17 |
1 |
| 14 |
34737351 | Lactate activates hypothalamic POMC neurons by intercellular signaling. | 2021 Nov 4 |
2 |
| 15 |
31395464 | Monocarboxylate transporters in cancer. | 2020 Mar |
1 |
| 16 |
31666207 | A lactate-induced Snail/STAT3 pathway drives GPR81 expression in lung cancer cells. | 2020 Jan 1 |
7 |
| 17 |
31836453 | Lactate/GPR81 signaling and proton motive force in cancer: Role in angiogenesis, immune escape, nutrition, and Warburg phenomenon. | 2020 Feb |
3 |
| 18 |
32113910 | Lactate as a fulcrum of metabolism. | 2020 Aug |
1 |
| 19 |
32268113 | Why Warburg Works: Lactate Controls Immune Evasion through GPR81. | 2020 Apr 7 |
3 |
| 20 |
32294462 | Lactate enhances Arc/arg3.1 expression through hydroxycarboxylic acid receptor 1-β-arrestin2 pathway in astrocytes. | 2020 Jul |
9 |
| 21 |
32325281 | Curcumin circumvent lactate-induced chemoresistance in hepatic cancer cells through modulation of hydroxycarboxylic acid receptor-1. | 2020 Jun |
4 |
| 22 |
32342523 | The roles of GRP81 as a metabolic sensor and inflammatory mediator. | 2020 Dec |
4 |
| 23 |
32649519 | Lactate induces alternative polarization (M2) of macrophages under lipopolysaccharide stimulation in vitro through G-protein coupled receptor 81. | 2020 Jul 20 |
1 |
| 24 |
32917658 | Lactate-Modulated Immunosuppression of Myeloid-Derived Suppressor Cells Contributes to the Radioresistance of Pancreatic Cancer. | 2020 Nov |
2 |
| 25 |
33123172 | Lactate Suppresses Macrophage Pro-Inflammatory Response to LPS Stimulation by Inhibition of YAP and NF-κB Activation via GPR81-Mediated Signaling. | 2020 |
3 |
| 26 |
33296645 | HCAR1/MCT1 Regulates Tumor Ferroptosis through the Lactate-Mediated AMPK-SCD1 Activity and Its Therapeutic Implications. | 2020 Dec 8 |
3 |
| 27 |
31440253 | Lactate Induces Pro-tumor Reprogramming in Intratumoral Plasmacytoid Dendritic Cells. | 2019 |
1 |
| 28 |
29704292 | Modulation of hippocampal excitability via the hydroxycarboxylic acid receptor 1. | 2018 Aug |
1 |
| 29 |
29913143 | Lactate enhanced the effect of parathyroid hormone on osteoblast differentiation via GPR81-PKC-Akt signaling. | 2018 Sep 5 |
3 |
| 30 |
30728759 | Glycolysis-Derived Compounds From Astrocytes That Modulate Synaptic Communication. | 2018 |
1 |
| 31 |
28258841 | Stimulation of lactate receptor (HCAR1) affects cellular DNA repair capacity. | 2017 Apr |
3 |
| 32 |
28512002 | Cell-surface G-protein-coupled receptors for tumor-associated metabolites: A direct link to mitochondrial dysfunction in cancer. | 2017 Aug |
2 |
| 33 |
28604752 | Tumor cell-derived lactate induces TAZ-dependent upregulation of PD-L1 through GPR81 in human lung cancer cells. | 2017 Oct 19 |
2 |
| 34 |
28762551 | Monocarboxylate transporter 1 is a key player in glioma-endothelial cell crosstalk. | 2017 Dec |
1 |
| 35 |
29021365 | Lactic Acid: No Longer an Inert and End-Product of Glycolysis. | 2017 Nov |
1 |
| 36 |
29151072 | The lactate receptor (HCAR1/GPR81) contributes to doxorubicin chemoresistance via ABCB1 transporter up-regulation in human cervical cancer HeLa cells. | 2017 Aug |
1 |
| 37 |
27645401 | Induction of triglyceride accumulation and mitochondrial maintenance in muscle cells by lactate. | 2016 Sep 20 |
2 |
| 38 |
27765922 | G-protein-coupled receptor 81 promotes a malignant phenotype in breast cancer through angiogenic factor secretion. | 2016 Oct 25 |
2 |
| 39 |
24248427 | Monocarboxylate transporters in temporal lobe epilepsy: roles of lactate and ketogenic diet. | 2015 Jan |
1 |
| 40 |
25425080 | Lactate transport and signaling in the brain: potential therapeutic targets and roles in body-brain interaction. | 2015 Feb |
2 |
| 41 |
25881750 | The lactate receptor, G-protein-coupled receptor 81/hydroxycarboxylic acid receptor 1: Expression and action in brain. | 2015 Jul |
5 |
| 42 |
23696276 | Lactate receptor sites link neurotransmission, neurovascular coupling, and brain energy metabolism. | 2014 Oct |
2 |
| 43 |
24904266 | Lactate transport and receptor actions in cerebral malaria. | 2014 |
1 |
| 44 |
24928781 | Cell surface lactate receptor GPR81 is crucial for cancer cell survival. | 2014 Sep 15 |
2 |
| 45 |
22457647 | Is lactate a volume transmitter of metabolic states of the brain? | 2012 |
1 |
| 46 |
21454438 | International Union of Basic and Clinical Pharmacology. LXXXII: Nomenclature and Classification of Hydroxy-carboxylic Acid Receptors (GPR81, GPR109A, and GPR109B). | 2011 Jun |
2 |
| 47 |
21862690 | Study of GPR81, the lactate receptor, from distant species identifies residues and motifs critical for GPR81 functions. | 2011 Nov |
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| 48 |
21902860 | Lactate and the GPR81 receptor in metabolic regulation: implications for adipose tissue function and fatty acid utilisation by muscle during exercise. | 2011 Nov |
3 |
| 49 |
22654812 | Biological roles and therapeutic potential of hydroxy-carboxylic Acid receptors. | 2011 |
2 |
| 50 |
18952058 | Role of GPR81 in lactate-mediated reduction of adipose lipolysis. | 2008 Dec 19 |
4 |