Guanine Nucleotides

dedicator of cytokinesis 1 ; Homo sapiens







18 Article(s)
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1 33660564 Biallelic ELMO3 mutations and loss of function for DOCK-mediated RAC1 activation result in intellectual disability. 2021 Mar 4 1
2 30108175 HGF-induced formation of the MET-AXL-ELMO2-DOCK180 complex promotes RAC1 activation, receptor clustering, and cancer cell migration and invasion. 2018 Oct 5 1
3 23441967 The scaffolding protein GRASP/Tamalin directly binds to Dock180 as well as to cytohesins facilitating GTPase crosstalk in epithelial cell migration. 2013 Feb 26 1
4 22647486 A shortcut from GPCR signaling to Rac-mediated actin cytoskeleton through an ELMO/DOCK complex. 2012 Jul-Sep 2
5 21283588 The DOCK protein sponge binds to ELMO and functions in Drosophila embryonic CNS development. 2011 Jan 25 1
6 22175896 Overexpression of dedicator of cytokinesis I (Dock180) in ovarian cancer correlated with aggressive phenotype and poor patient survival. 2011 Dec 1
7 20237902 The role of Crk/Dock180/Rac1 pathway in the malignant behavior of human ovarian cancer cell SKOV3. 2010 Jan 1
8 20958313 ELMO1 signaling in apoptotic germ cell clearance and spermatogenesis. 2010 Oct 1
9 18066058 Netrin signal transduction and the guanine nucleotide exchange factor DOCK180 in attractive signaling. 2008 Jan 1
10 18332221 Myoblasts and macrophages share molecular components that contribute to cell-cell fusion. 2008 Mar 10 1
11 18596235 The DHR1 domain of DOCK180 binds to SNX5 and regulates cation-independent mannose 6-phosphate receptor transport. 2008 Sep 2
12 17570359 RhoG regulates anoikis through a phosphatidylinositol 3-kinase-dependent mechanism. 2007 Aug 1 1
13 17765544 GEF what? Dock180 and related proteins help Rac to polarize cells in new ways. 2007 Aug 1
14 16968698 Identification of a DOCK180-related guanine nucleotide exchange factor that is capable of mediating a positive feedback activation of Cdc42. 2006 Nov 17 1
15 15710388 Zizimin2: a novel, DOCK180-related Cdc42 guanine nucleotide exchange factor expressed predominantly in lymphocytes. 2005 Feb 14 1
16 15723800 A Steric-inhibition model for regulation of nucleotide exchange via the Dock180 family of GEFs. 2005 Feb 22 2
17 12879077 RhoG activates Rac1 by direct interaction with the Dock180-binding protein Elmo. 2003 Jul 24 1
18 12432077 Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity. 2002 Dec 15 1