asoxime chloride

acetylcholinesterase ; Mus musculus







20 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 26730700 Rapid-releasing of HI-6 via brain-targeted mesoporous silica nanoparticles for nerve agent detoxification. 2016 May 5 2
2 27083141 HI-6 assisted catalytic scavenging of VX by acetylcholinesterase choline binding site mutants. 2016 Nov 25 1
3 27140636 Structure of a prereaction complex between the nerve agent sarin, its biological target acetylcholinesterase, and the antidote HI-6. 2016 May 17 1
4 23376121 Catalytic-site conformational equilibrium in nerve-agent adducts of acetylcholinesterase: possible implications for the HI-6 antidote substrate specificity. 2013 May 1 1
5 19732756 Crystal structures of oxime-bound fenamiphos-acetylcholinesterases: reactivation involving flipping of the His447 ring to form a reactive Glu334-His447-oxime triad. 2010 Feb 1 1
6 20140002 Differential binding of bispyridinium oxime drugs with acetylcholinesterase. 2010 Mar 1
7 17046138 Mutation of acetylcholinesterase to enhance oxime-assisted catalytic turnover of methylphosphonates. 2007 Apr 20 1
8 16598855 Active site mutant acetylcholinesterase interactions with 2-PAM, HI-6, and DDVP. 2006 Apr 14 1
9 16876764 Crystal structures of acetylcholinesterase in complex with HI-6, Ortho-7 and obidoxime: structural basis for differences in the ability to reactivate tabun conjugates. 2006 Aug 28 3
10 15023072 Mutant cholinesterases possessing enhanced capacity for reactivation of their phosphonylated conjugates. 2004 Mar 23 2
11 15446360 The influence of the time of antidotal treatment administration on its effectiveness against tabun-induced poisoning in mice. 2004 1
12 12907237 Two possible orientations of the HI-6 molecule in the reactivation of organophosphate-inhibited acetylcholinesterase. 2003 Aug 1 4
13 10421446 Role of edrophonium in prevention of the re-inhibition of acetylcholinesterase by phosphorylated oxime. 1999 May 14 2
14 10421479 Improvements in scavenger protection against organophosphorus agents by modification of cholinesterases. 1999 May 14 2
15 9271331 Mutant acetylcholinesterases as potential detoxification agents for organophosphate poisoning. 1997 Jul 15 7
16 8304979 Amplification of the effectiveness of acetylcholinesterase for detoxification of organophosphorus compounds by bis-quaternary oximes. 1994 Jan 20 2
17 2052186 The role of carboxylesterase in species variation of oxime protection against soman. 1991 Spring 1
18 6327447 Isolation, in vitro activity, and acute toxicity in mice of the four stereoisomers of soman. 1984 Apr 1
19 6710485 Isolation, anticholinesterase properties, and acute toxicity in mice of the four stereoisomers of the nerve agent soman. 1984 Jan 1
20 7184784 The treatment of Soman poisoning and its perspectives. 1981 Mar-Apr 1