Donepezil

acetylcholinesterase ; Mus musculus







59 Article(s)
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1 34776532 Influence of ligand geometry on cholinesterase enzyme - A comparison of 1-isoindolinone based structural analog with Donepezil. 2022 Jan 5 1
2 35203483 Vitisin A, a Resveratrol Tetramer, Improves Scopolamine-Induced Impaired Learning and Memory Functions in Amnesiac ICR Mice. 2022 Jan 26 1
3 33851543 Autonomic and cholinergic mechanisms mediating cardiovascular and temperature effects of donepezil in conscious mice. 2021 Jun 1 1
4 34515019 Investigating Neuroprotective Potential of Berberine, Levetiracetam and Their Combination in The Management of Alzheimer's Disease Utilizing Drug Repurposing Strategy. 2021 Sep 9 1
5 32118214 Acetylcholinesterase inhibitory activity and neuroprotection in vitro, molecular docking, and improved learning and memory functions of demethylcurcumin in scopolamine-induced amnesia ICR mice. 2020 Mar 1 1
6 32184102 Inhibition of acetylcholinesterase attenuated retinal inflammation via suppressing NF-κB activation. 2020 Jun 1
7 32872194 Simultaneous Blockade of Histamine H3 Receptors and Inhibition of Acetylcholine Esterase Alleviate Autistic-Like Behaviors in BTBR T+ tf/J Mouse Model of Autism. 2020 Aug 28 2
8 32953572 Acetylcholinesterase inhibition ameliorates retinal neovascularization and glial activation in oxygen-induced retinopathy. 2020 2
9 30626892 Central cholinergic neuronal degeneration promotes the development of postoperative cognitive dysfunction. 2019 Jul 1
10 31302713 Spatial memory deficits in mice induced by chemotherapeutic agents are prevented by acetylcholinesterase inhibitors. 2019 Sep 1
11 31402621 Donepezil increases resistance to induced seizures in a mouse model of Dravet syndrome. 2019 Aug 1
12 29463072 The Effects of Donepezil, an Acetylcholinesterase Inhibitor, on Impaired Learning and Memory in Rodents. 2018 May 1 1
13 29564727 Tacrine(10)-hupyridone, a dual-binding acetylcholinesterase inhibitor, potently attenuates scopolamine-induced impairments of cognition in mice. 2018 Aug 1
14 29761010 Central cholinergic system mediates working memory deficit induced by anesthesia/surgery in adult mice. 2018 May 2
15 28125507 Behavioural effects of novel multitarget anticholinesterasic derivatives in Alzheimer's disease. 2017 Apr 1
16 28286520 Acetylcholinesterase Inhibitors Assay Using Colorimetric pH Sensitive Strips and Image Analysis by a Smartphone. 2017 1
17 28613859 Donepezil-Based Central Acetylcholinesterase Inhibitors by Means of a "Bio-Oxidizable" Prodrug Strategy: Design, Synthesis, and in Vitro Biological Evaluation. 2017 Jul 13 2
18 25823512 Streptozotocin Induced Neurotoxicity Involves Alzheimer's Related Pathological Markers: a Study on N2A Cells. 2016 Jul 1
19 26554604 Dietary and donepezil modulation of mTOR signaling and neuroinflammation in the brain. 2016 Feb 2
20 27150930 Psychopharmacological Studies in Mice. 2016 1
21 27284332 Donepezil delays photoreceptor apoptosis induced by N-methyl-N-nitrosourea in mice. 2016 Jun 2
22 27291828 Donepezil, an acetylcholine esterase inhibitor, and ABT-239, a histamine H3 receptor antagonist/inverse agonist, require the integrity of brain histamine system to exert biochemical and procognitive effects in the mouse. 2016 Oct 2
23 27373848 Donepezil, an acetylcholinesterase inhibitor, attenuates LPS-induced inflammatory response in murine macrophage cell line RAW 264.7 through inhibition of nuclear factor kappa B translocation. 2016 Oct 15 3
24 27796293 Rapid and sustained cognitive recovery in APP/PS1 transgenic mice by co-administration of EPPS and donepezil. 2016 Oct 31 1
25 28096851 Acetylcholinesterase Inhibitor Improves Learning and Memory Impairment Induced by Toxoplasma gondii Infection. 2016 Apr-Jun 3
26 25744714 Donepezil attenuates Aβ-associated mitochondrial dysfunction and reduces mitochondrial Aβ accumulation in vivo and in vitro. 2015 Aug 2
27 25890242 Systemic lipopolysaccharide-mediated alteration of cortical neuromodulation involves increases in monoamine oxidase-A and acetylcholinesterase activity. 2015 Feb 25 1
28 26114860 Donepezil Regulates 1-Methyl-4-phenylpyridinium-Induced Microglial Polarization in Parkinson's Disease. 2015 Oct 21 1
29 26558196 The protective role of tacrine and donepezil in the retina of acetylcholinesterase knockout mice. 2015 2
30 27441211 Donepezil prevents RANK-induced bone loss via inhibition of osteoclast differentiation by downregulating acetylcholinesterase. 2015 Sep 3
31 24214089 Reassessment of the role of the central cholinergic system. 2014 Jul 1
32 24487798 Donepezil enhances Purkinje cell survival and alleviates motor dysfunction by inhibiting cholesterol synthesis in a murine model of Niemann Pick disease type C. 2014 Mar 3
33 24911319 Donepezil reverses nicotine withdrawal-induced deficits in contextual fear conditioning in C57BL/6J mice. 2014 Oct 1
34 25036424 Donepezil and the alpha-7 agonist PHA 568487, but not risperidone, ameliorate spatial memory deficits in a subchronic MK-801 mouse model of cognitive impairment in schizophrenia. 2014 Oct 1 1
35 23147415 Mice heterozygous for AChE are more sensitive to AChE inhibitors but do not respond to BuChE inhibition. 2013 Apr 1
36 23276665 Characterization of cognitive deficits in a transgenic mouse model of Alzheimer's disease and effects of donepezil and memantine. 2013 Mar 5 1
37 22369073 Acetylcholinesterase inhibitors attenuate angiogenesis. 2012 Aug 1 1
38 22553034 Prior pathology in the basal forebrain cholinergic system predisposes to inflammation-induced working memory deficits: reconciling inflammatory and cholinergic hypotheses of delirium. 2012 May 2 1
39 22826038 Combined administration of cerebrolysin and donepezil induces plastic changes in prefrontal cortex in aged mice. 2012 Nov 2
40 21419082 [Effects of early intervention with Huannao Yicong formula effective components on behavior and cholinergic system of β-amyloid precursor protein transgenic mice]. 2011 Mar 2
41 21750701 Donepezil, anti-Alzheimer's disease drug, prevents cardiac rupture during acute phase of myocardial infarction in mice. 2011 1
42 21820013 Butyrylcholinesterase inhibitors ameliorate cognitive dysfunction induced by amyloid-β peptide in mice. 2011 Nov 20 1
43 21820453 Acetylcholinesterase inhibitors rapidly activate Trk neurotrophin receptors in the mouse hippocampus. 2011 Dec 1
44 22114680 Isoflurane-induced spatial memory impairment in mice is prevented by the acetylcholinesterase inhibitor donepezil. 2011 3
45 20219155 Galantamine ameliorates the impairment of recognition memory in mice repeatedly treated with methamphetamine: involvement of allosteric potentiation of nicotinic acetylcholine receptors and dopaminergic-ERK1/2 systems. 2010 Nov 1
46 20460870 [Donepezil-induced neuroprotection of acetylcholinergic neurons in olfactory bulbectomized mice]. 2010 May 2
47 20723895 Acetylcholinesterase inhibitors attenuate atherogenesis in apolipoprotein E-knockout mice. 2010 Nov 1
48 19318594 Donepezil improves cognitive function in mice by increasing the production of insulin-like growth factor-I in the hippocampus. 2009 Jul 1
49 19470293 Effects of rivastigmine and donepezil on brain acetylcholine levels in acetylcholinesterase-deficient mice. 2009 1
50 19799879 Effects of donepezil on amyloid-beta and synapse density in the Tg2576 mouse model of Alzheimer's disease. 2009 Dec 15 1