organophosphorus

acetylcholinesterase ; Mus musculus







34 Article(s)
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1 34969248 Loading and Sustained Release of Pralidoxime Chloride from Swellable MIL-88B(Fe) and Its Therapeutic Performance on Mice Poisoned by Neurotoxic Agents. 2022 Jan 24 2
2 33539933 AChR is partly responsible in mice depressive-like behavior after Phosalone exposure. 2021 Mar-Apr 1
3 32833441 Inhibition of Acetylcholinesterases by Stereoisomeric Organophosphorus Compounds Containing Both Thioester and p-Nitrophenyl Leaving Groups. 2020 Sep 21 2
4 31207225 Slight difference in the isomeric oximes K206 and K203 makes huge difference for the reactivation of organophosphorus-inhibited AChE: Theoretical and experimental aspects. 2019 Aug 25 1
5 26972668 An easy method for the determination of active concentrations of cholinesterase reactivators in blood samples: Application to the efficacy assessment of non quaternary reactivators compared to HI-6 and pralidoxime in VX-poisoned mice. 2017 Apr 1 2
6 25618550 Long-term and low-dose malathion exposure causes cognitive impairment in adult mice: evidence of hippocampal mitochondrial dysfunction, astrogliosis and apoptotic events. 2016 Mar 2
7 27083141 HI-6 assisted catalytic scavenging of VX by acetylcholinesterase choline binding site mutants. 2016 Nov 25 2
8 27140636 Structure of a prereaction complex between the nerve agent sarin, its biological target acetylcholinesterase, and the antidote HI-6. 2016 May 17 2
9 21948870 Delayed reduction of hippocampal synaptic transmission and spines following exposure to repeated subclinical doses of organophosphorus pesticide in adult mice. 2012 Jan 2
10 22209767 Differential sensitivity of plasma carboxylesterase-null mice to parathion, chlorpyrifos and chlorpyrifos oxon, but not to diazinon, dichlorvos, diisopropylfluorophosphate, cresyl saligenin phosphate, cyclosarin thiocholine, tabun thiocholine, and carbofuran. 2012 Feb 5 2
11 22240983 Repeated exposure to sublethal doses of the organophosphorus compound VX activates BDNF expression in mouse brain. 2012 Apr 2
12 22406659 Mice treated with a nontoxic dose of chlorpyrifos oxon have diethoxyphosphotyrosine labeled proteins in blood up to 4 days post exposure, detected by mass spectrometry. 2012 May 16 2
13 21723318 Effects of K074 and pralidoxime on antioxidant and acetylcholinesterase response in malathion-poisoned mice. 2011 Dec 2
14 21767560 Induction of plasma acetylcholinesterase activity in mice challenged with organophosphorus poisons. 2011 Sep 1 2
15 19732756 Crystal structures of oxime-bound fenamiphos-acetylcholinesterases: reactivation involving flipping of the His447 ring to form a reactive Glu334-His447-oxime triad. 2010 Feb 1 1
16 20423708 Nerve agent exposure elicits site-specific changes in protein phosphorylation in mouse brain. 2010 Jun 25 2
17 17402711 Crystal structures of acetylcholinesterase in complex with organophosphorus compounds suggest that the acyl pocket modulates the aging reaction by precluding the formation of the trigonal bipyramidal transition state. 2007 Apr 24 1
18 16782588 The acute toxicity of acetylcholinesterase reactivators in mice in relation to their structure. 2006 Jun 2
19 17192653 Interaction of pyridinium oximes with acetylcholinesterase and their effect on organophosphate-poisoned mice. 2006 1
20 21783513 Life without acetylcholinesterase: the implications of cholinesterase inhibitor toxicity in AChE-knockout mice. 2005 May 2
21 15356346 Increased susceptibility to adult paraoxon exposure in mice neonatally exposed to nicotine. 2004 Dec 1
22 11350214 Fatty acid amide hydrolase inhibition by neurotoxic organophosphorus pesticides. 2001 May 15 1
23 10869390 Postnatal developmental delay and supersensitivity to organophosphate in gene-targeted mice lacking acetylcholinesterase. 2000 Jun 1
24 10898598 Phosphoacetylcholinesterase: toxicity of phosphorus oxychloride to mammals and insects that can be attributed to selective phosphorylation of acetylcholinesterase by phosphorodichloridic acid. 2000 Jul 2
25 10915041 Synthesis of fluorescent probes directed to the active site gorge of acetylcholinesterase. 2000 Jul 17 1
26 11053548 Interactions of the organophosphates paraoxon and methyl paraoxon with mouse brain acetylcholinesterase. 2000 Nov 1
27 10403635 Success of pyridostigmine, physostigmine, eptastigmine and phosphotriesterase treatments in acute sarin intoxication. 1999 Jun 15 2
28 9074804 Acephate insecticide toxicity: safety conferred by inhibition of the bioactivating carboxyamidase by the metabolite methamidophos. 1997 Jan 2
29 7566687 In vitro effect of chlorpyrifos oxon on muscarinic receptors and adenylate cyclase. 1995 Summer 1
30 8304979 Amplification of the effectiveness of acetylcholinesterase for detoxification of organophosphorus compounds by bis-quaternary oximes. 1994 Jan 20 1
31 3653568 Acetylcholinesterase prophylaxis against organophosphate toxicity. 1987 Aug 2
32 20493132 Interaction of a bisquaternary ammonium compound with the peripheral organophosphorus (POP) site on acetylcholinesterase. 1986 1
33 6710513 Profenofos insecticide bioactivation in relation to antidote action and the stereospecificity of acetylcholinesterase inhibition, reactivation, and aging. 1984 Mar 30 2
34 6673794 Recovery of acetylcholinesterase and of its multiple molecular forms in motor end-plate-free and motor end-plate-rich regions of mouse striated muscle, after irreversible inactivation by an organophosphorus compound (methyl-phosphorothiolate derivative). 1983 2