Cisplatin

TNF superfamily member 10 ; Homo sapiens







81 Article(s)
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1 34827096 Chemo-Sensitization of CD133+ Cancer Stem Cell Enhances the Effect of Mesenchymal Stem Cell Expressing TRAIL in Non-Small Cell Lung Cancer Cell Lines. 2021 Oct 26 4
2 32020226 Tumor necrosis factor‑related apoptosis‑inducing ligand as a therapeutic option in urothelial cancer cells with acquired resistance against first‑line chemotherapy. 2020 Apr 1
3 32368398 Cisplatin sensitivity mediated by NKX2-1 in lung adenocarcinoma is dependent on p53 mutational status via modulating TNFSF10 expression. 2020 3
4 30724400 Inhibition of N-myc expression sensitizes human neuroblastoma IMR-32 cells expressing caspase-8 to TRAIL. 2019 May 2
5 30805008 Human Embryonic Stem Cells Acquire Responsiveness to TRAIL upon Exposure to Cisplatin. 2019 2
6 31498788 Designing combination therapies with modeling chaperoned machine learning. 2019 Sep 1
7 29849953 Epigenetic silencing of miR-200b is associated with cisplatin resistance in bladder cancer. 2018 May 11 2
8 28202521 Ex Vivo Explant Cultures of Non-Small Cell Lung Carcinoma Enable Evaluation of Primary Tumor Responses to Anticancer Therapy. 2017 Apr 15 1
9 28671676 JWA regulates TRAIL-induced apoptosis via MARCH8-mediated DR4 ubiquitination in cisplatin-resistant gastric cancer cells. 2017 Jul 3 3
10 29182622 Cisplatin or LA-12 enhance killing effects of TRAIL in prostate cancer cells through Bid-dependent stimulation of mitochondrial apoptotic pathway but not caspase-10. 2017 2
11 29297126 The effect of cisplatin on cytotoxicity of anticancer cytokine TRAIL and its receptor-selective mutant variant DR5-B1. 2017 Nov 3
12 26542757 Epigenetic inactivation of TRAIL decoy receptors at 8p12-21.3 commonly deleted region confers sensitivity to Apo2L/trail-Cisplatin combination therapy in cervical cancer. 2016 Feb 2
13 26794656 Flavonol and imidazole derivatives block HPV16 E6 activities and reactivate apoptotic pathways in HPV⁺ cells. 2016 Jan 21 1
14 27035109 Mild oxidative stress induced by a low dose of cisplatin contributes to the escape of TRAIL-mediated apoptosis in the ovarian cancer SKOV3 cell line. 2016 Jun 6
15 25186100 Combination of systemic chemotherapy with local stem cell delivered S-TRAIL in resected brain tumors. 2015 Jan 2
16 25695324 Inhibition of livin expression suppresses cell proliferation and enhances chemosensitivity to cisplatin in human lung adenocarcinoma cells. 2015 Jul 1
17 25796504 Cisplatin-mediated c-myc overexpression and cytochrome c (cyt c) release result in the up-regulation of the death receptors DR4 and DR5 and the activation of caspase 3 and caspase 9, likely responsible for the TRAIL-sensitizing effect of cisplatin. 2015 Apr 5
18 26463141 [Molecular mechanism of cisplatin to enhance the ability of TRAIL in reversing multidrug resistance in gastric cancer cells]. 2015 Jun 3
19 26492363 Activation of surrogate death receptor signaling triggers peroxynitrite-dependent execution of cisplatin-resistant cancer cells. 2015 Oct 22 4
20 24345465 Improved apoptotic cell death in drug-resistant non-small-cell lung cancer cells by tumor necrosis factor-related apoptosis-inducing ligand-based treatment. 2014 Mar 2
21 25285768 Platinum(IV) complex LA-12 exerts higher ability than cisplatin to enhance TRAIL-induced cancer cell apoptosis via stimulation of mitochondrial pathway. 2014 Dec 1 2
22 23258590 Absence of death receptor translocation into lipid rafts in acquired TRAIL-resistant NSCLC cells. 2013 Feb 1
23 23826494 Synergistic Effect of Subtoxic-dose Cisplatin and TRAIL to Mediate Apoptosis by Down-regulating Decoy Receptor 2 and Up-regulating Caspase-8, Caspase-9 and Bax Expression on NCI-H460 and A549 Cells. 2013 May 4
24 23846221 Development of a human three-dimensional organotypic skin-melanoma spheroid model for in vitro drug testing. 2013 Jul 11 2
25 23912708 Combination of Ad-sTRAIL with the chemotherapeutic drug cisplatin synergistically enhances their pro-apoptotic ability in human breast cancer cells. 2013 Oct 1
26 20856198 Caspase-3 cleaves XIAP in a positive feedback loop to sensitize melanoma cells to TRAIL-induced apoptosis. 2011 Feb 3 1
27 20876774 Identification of c-FLIP(L) and c-FLIP(S) as critical regulators of death receptor-induced apoptosis in pancreatic cancer cells. 2011 Feb 3
28 21037225 Cisplatin and a potent platinum(IV) complex-mediated enhancement of TRAIL-induced cancer cells killing is associated with modulation of upstream events in the extrinsic apoptotic pathway. 2011 Jan 5
29 21152876 Cisplatin sensitizes human hepatocellular carcinoma cells, but not hepatocytes and mesenchymal stem cells, to TRAIL within a therapeutic window partially depending on the upregulation of DR5. 2011 Feb 3
30 21252285 Enhanced anticancer effect of the combination of cisplatin and TRAIL in triple-negative breast tumor cells. 2011 Mar 1
31 21291526 Synergistic antitumor effect of AAV-mediated TRAIL expression combined with cisplatin on head and neck squamous cell carcinoma. 2011 Feb 3 5
32 21487429 Drug-induced caspase 8 upregulation sensitises cisplatin-resistant ovarian carcinoma cells to rhTRAIL-induced apoptosis. 2011 Apr 12 1
33 21877938 Cisplatin restores TRAIL apoptotic pathway in glioblastoma-derived stem cells through up-regulation of DR5 and down-regulation of c-FLIP. 2011 Oct 2
34 22093622 [Cisplatin enhances TRAIL-induced apoptosis in gastric cancer cells through clustering death receptor 4 into lipid rafts]. 2011 Jul 5
35 20157422 The prosurvival activity of ascites against TRAIL is associated with a shorter disease-free interval in patients with ovarian cancer. 2010 Jan 18 2
36 20213096 The efficacy of combination therapy using adeno-associated virus-TRAIL targeting to telomerase activity and cisplatin in a mice model of hepatocellular carcinoma. 2010 Dec 4
37 20623264 Cisplatin-enhanced sensitivity of glioblastoma multiforme U251 cells to adenovirus-delivered TRAIL in vitro. 2010 Dec 3
38 19590723 TRAIL-induced cell death and caspase-8 activation are inhibited by cisplatin but not carboplatin. 2009 Jun 5
39 19625063 Oxidative stress sensitizes bladder cancer cells to TRAIL mediated apoptosis by down-regulating anti-apoptotic proteins. 2009 Sep 1
40 19661294 Cytotoxic effects of camptothecin and cisplatin combined with tumor necrosis factor-related apoptosis-inducing ligand (Apo2L/TRAIL) in a model of primary culture of non-small cell lung cancer. 2009 Aug 2
41 19834905 Identification of molecular targets for selective elimination of TRAIL-resistant leukemia cells. From spots to in vitro assays using TOP15 charts. 2009 Nov 1
42 19852930 Association of caspase-8 mutation with chemoresistance to cisplatin in HOC313 head and neck squamous cell carcinoma cells. 2009 Dec 18 1
43 19957654 [Synergistic effects and mechanisms of combined tumor necrosis factor-related apoptosis-inducing ligand and chemotherapeutic drugs or radiotherapy in killing laryngeal squamous carcinoma cells in vitro]. 2009 Jul 3
44 18191995 Cisplatin-mediated sensitivity to TRAIL-induced cell death in human granulosa tumor cells. 2008 Mar 7
45 18309355 Cisplatin enhances the antitumor effect of tumor necrosis factor-related apoptosis-inducing ligand gene therapy via recruitment of the mitochondria-dependent death signaling pathway. 2008 Jun 5
46 17376311 Induction of apoptosis in osteogenic sarcoma cells by combination of tumor necrosis factor-related apoptosis inducing ligand and chemotherapeutic agents. 2007 Mar 5 2
47 17379655 Tumor necrosis factor-related apoptosis inducing ligand expression and activity in hen granulosa cells. 2007 Mar 2
48 17441316 Combination of gamma-interferon with TRAIL and cisplatin or etoposide induces apoptosis in human neuroblastoma cell line SH-SY5Y. 2007 Mar 2
49 17577631 Synergistic induction of tumor cell death by combining cisplatin with an oncolytic adenovirus carrying TRAIL. 2007 Oct 3
50 17693058 Inhibition of RIP and c-FLIP enhances TRAIL-induced apoptosis in pancreatic cancer cells. 2007 Nov 1