109 Article(s)Download |
PMID | Title | Pub. Year | #Total Relationships |
51 | 21247791 | Geranylgeraniol - a new potential therapeutic approach to bisphosphonate associated osteonecrosis of the jaw. | 2011 Mar | 1 |
52 | 21335425 | Bisphosphonates induce autophagy by depleting geranylgeranyl diphosphate. | 2011 May | 2 |
53 | 21420384 | Correlation between time-dependent inhibition of human farnesyl pyrophosphate synthase and blockade of mevalonate pathway by nitrogen-containing bisphosphonates in cultured cells. | 2011 Apr 22 | 2 |
54 | 21465521 | Bisphosphonates, specific inhibitors of osteoclast function and a class of drugs for osteoporosis therapy. | 2011 May | 1 |
55 | 21497677 | The relationship between the chemistry and biological activity of the bisphosphonates. | 2011 Jul | 2 |
56 | 21555003 | Bisphosphonates: the first 40 years. | 2011 Jul | 4 |
57 | 21702715 | Farnesyl pyrophosphate synthase modulators: a patent review (2006 - 2010). | 2011 Sep | 2 |
58 | 22091898 | Bisphosphonates and osteonecrosis of the jaw. | 2011 Dec | 1 |
59 | 19819230 | Mevalonate pathway intermediates downregulate zoledronic acid-induced isopentenyl pyrophosphate and ATP analog formation in human breast cancer cells. | 2010 Mar 1 | 1 |
60 | 20191015 | Genetic polymorphism of geranylgeranyl diphosphate synthase (GGSP1) predicts bone density response to bisphosphonate therapy in Korean women. | 2010 Mar | 2 |
61 | 20299227 | Synthesis and preliminary pharmacological characterisation of a new class of nitrogen-containing bisphosphonates (N-BPs). | 2010 Apr 1 | 1 |
62 | 20450493 | Sterol-regulatory-element-binding protein 2 and nuclear factor Y control human farnesyl diphosphate synthase expression and affect cell proliferation in hepatoblastoma cells. | 2010 Jul 15 | 1 |
63 | 20533067 | Profound hypocalcemia following effective response to zoledronic acid treatment in a patient with juvenile Paget's disease. | 2010 Nov | 1 |
64 | 20539033 | Bisphosphonate therapeutics in bone disease: the hard and soft data on osteoclast inhibition. | 2010 Jun | 1 |
65 | 20544107 | Discovery of potent inhibitor for farnesyl pyrophosphate synthase in the mevalonate pathway. | 2010 Aug 7 | 2 |
66 | 20711197 | Allosteric non-bisphosphonate FPPS inhibitors identified by fragment-based discovery. | 2010 Sep | 2 |
67 | 20722616 | Bisphosphonates: molecular mechanisms of action and effects on bone cells, monocytes and macrophages. | 2010 | 2 |
68 | 20801032 | Novel bisphosphonate inhibitors of the human farnesyl pyrophosphate synthase. | 2010 Oct 1 | 3 |
69 | 20832326 | Synthesis and biological evaluation of a series of aromatic bisphosphonates. | 2010 Oct 15 | 1 |
70 | 19016713 | Peripheral blood monocytes are responsible for gammadelta T cell activation induced by zoledronic acid through accumulation of IPP/DMAPP. | 2009 Jan | 1 |
71 | 19233551 | Bisphosphonate zoledronic acid enhances the inhibitory effects of gefitinib on EGFR-mutated non-small cell lung carcinoma cells. | 2009 Jun 8 | 1 |
72 | 19309137 | Lipophilic bisphosphonates as dual farnesyl/geranylgeranyl diphosphate synthase inhibitors: an X-ray and NMR investigation. | 2009 Apr 15 | 2 |
73 | 19371349 | Zoledronic acid induces formation of a pro-apoptotic ATP analogue and isopentenyl pyrophosphate in osteoclasts in vivo and in MCF-7 cells in vitro. | 2009 Jun | 1 |
74 | 19665949 | Analysis of endogenous ATP analogs and mevalonate pathway metabolites in cancer cell cultures using liquid chromatography-electrospray ionization mass spectrometry. | 2009 Oct 1 | 1 |
75 | 19699819 | The level of ATP analog and isopentenyl pyrophosphate correlates with zoledronic acid-induced apoptosis in cancer cells in vitro. | 2009 Dec | 2 |
76 | 19810397 | Bisphosphonates and osteonecrosis of the jaw--current thoughts. | 2009 Sep | 1 |
77 | 18214569 | Mechanisms of action of bisphosphonates: similarities and differences and their potential influence on clinical efficacy. | 2008 Jun | 2 |
78 | 18327899 | Structure-activity relationships among the nitrogen containing bisphosphonates in clinical use and other analogues: time-dependent inhibition of human farnesyl pyrophosphate synthase. | 2008 Apr 10 | 1 |
79 | 18442135 | Structures of a potent phenylalkyl bisphosphonate inhibitor bound to farnesyl and geranylgeranyl diphosphate synthases. | 2008 Nov 1 | 2 |
80 | 18454049 | Bisphosphonate-induced ATP analog formation and its effect on inhibition of cancer cell growth. | 2008 Apr | 1 |
81 | 18463892 | Rab proteins and Rab-associated proteins: major actors in the mechanism of protein-trafficking disorders. | 2008 Jul | 1 |
82 | 18473904 | Structural analysis of farnesyl pyrophosphate synthase from parasitic protozoa, a potential chemotherapeutic target. | 2008 Mar | 2 |
83 | 18800762 | Inhibition of geranylgeranyl diphosphate synthase by bisphosphonates: a crystallographic and computational investigation. | 2008 Sep 25 | 1 |
84 | 16996129 | Inhibitors of the mevalonate pathway as potential therapeutic agents in multiple myeloma. | 2007 Mar | 1 |
85 | 17277961 | [Introduction to bisphosphonates. History and functional mechanisms]. | 2007 Feb | 1 |
86 | 17291279 | Nonpeptide antigens, presentation mechanisms, and immunological memory of human Vgamma2Vdelta2 T cells: discriminating friend from foe through the recognition of prenyl pyrophosphate antigens. | 2007 Feb | 1 |
87 | 17535895 | Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases. | 2007 Jun 12 | 2 |
88 | 17959891 | Mechanism of action, pharmacokinetic and pharmacodynamic profile, and clinical applications of nitrogen-containing bisphosphonates. | 2007 Nov | 1 |
89 | 18056045 | Bisphosphonates: an update on mechanisms of action and how these relate to clinical efficacy. | 2007 Nov | 2 |
90 | 22460750 | Pharmacokinetic profile of bisphosphonates in the treatment of metabolic bone disorders. | 2007 Jan | 1 |
91 | 16216433 | Minodronate, a nitrogen-containing bisphosphonate, is a promising remedy for treating patients with diabetic retinopathy. | 2006 | 1 |
92 | 16650801 | Recent advances in understanding the mechanism of action of bisphosphonates. | 2006 Jun | 1 |
93 | 16684881 | The molecular mechanism of nitrogen-containing bisphosphonates as antiosteoporosis drugs. | 2006 May 16 | 2 |
94 | 16831938 | Bisphosphonates: from bench to bedside. | 2006 Apr | 4 |
95 | 16892359 | Structural basis for the exceptional in vivo efficacy of bisphosphonate drugs. | 2006 Feb | 4 |
96 | 16932286 | Drug insight: Bisphosphonates for postmenopausal osteoporosis. | 2006 Apr | 1 |
97 | 16956297 | Investigation of the catalytic mechanism of farnesyl pyrophosphate synthase by computer simulation. | 2006 Sep 14 | 2 |
98 | 17062705 | Molecular mechanisms of action of bisphosphonates: current status. | 2006 Oct 15 | 2 |
99 | 17090032 | Solid-state NMR, crystallographic, and computational investigation of bisphosphonates and farnesyl diphosphate synthase-bisphosphonate complexes. | 2006 Nov 15 | 2 |
100 | 15828834 | Pyridinium-1-yl bisphosphonates are potent inhibitors of farnesyl diphosphate synthase and bone resorption. | 2005 Apr 21 | 2 |