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30982438 | Measuring the structural impact of mutations on cytochrome P450 21A2, the major steroid 21-hydroxylase related to congenital adrenal hyperplasia. | 2020 Mar |
1 |
| 2 |
32203088 | Extra-adrenal glucocorticoid biosynthesis: implications for autoimmune and inflammatory disorders. | 2020 May |
1 |
| 3 |
32610579 | Non-Classic Disorder of Adrenal Steroidogenesis and Clinical Dilemmas in 21-Hydroxylase Deficiency Combined with Backdoor Androgen Pathway. Mini-Review and Case Report. | 2020 Jun 29 |
1 |
| 4 |
28893623 | CYP17A1 inhibitor abiraterone, an anti-prostate cancer drug, also inhibits the 21-hydroxylase activity of CYP21A2. | 2017 Nov |
1 |
| 5 |
26514241 | Novel functionalized 5-(phenoxymethyl)-1,3-dioxane analogs exhibiting cytochrome P450 inhibition: a patent evaluation WO2015048311 (A1). | 2016 |
2 |
| 6 |
26941069 | The experience of women living with Congenital Adrenal Hyperplasia: impact of the condition and the care given. | 2016 Jul |
1 |
| 7 |
27789139 | Design, synthesis, and evaluation of (2S,4R)-Ketoconazole sulfonamide analogs as potential treatments for Metabolic Syndrome. | 2016 Dec 1 |
1 |
| 8 |
26374204 | A CYP21A2 based whole-cell system in Escherichia coli for the biotechnological production of premedrol. | 2015 Sep 15 |
1 |
| 9 |
24466573 | Effects of novel brominated flame retardants on steroidogenesis in primary porcine testicular cells. | 2014 Jan 3 |
1 |
| 10 |
25210767 | Common genetic variants of the human steroid 21-hydroxylase gene (CYP21A2) are related to differences in circulating hormone levels. | 2014 |
1 |
| 11 |
23084589 | Effects of polycyclic musks HHCB and AHTN on steroidogenesis in H295R cells. | 2013 Jan |
1 |
| 12 |
22886582 | Complement component 4 copy number variation and CYP21A2 genotype associations in patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency. | 2012 Dec |
1 |
| 13 |
21094146 | Steroid synthesis by primary human keratinocytes; implications for skin disease. | 2011 Jan 7 |
1 |
| 14 |
21446712 | Why human cytochrome P450c21 is a progesterone 21-hydroxylase. | 2011 May 17 |
1 |
| 15 |
20423741 | Novel intronic CYP21A2 mutation in a Japanese patient with classic salt-wasting steroid 21-hydroxylase deficiency. | 2010 Nov |
1 |
| 16 |
17400813 | Expression of molecular equivalent of hypothalamic-pituitary-adrenal axis in adult retinal pigment epithelium. | 2007 Apr |
1 |
| 17 |
15128284 | Modulation of steroidogenic enzymes by orphan nuclear transcriptional regulation may control diverse production of cortisol and androgens in the human adrenal. | 2004 May |
1 |
| 18 |
14513879 | Steroid 21-hydroxylase (P450c21) naturally occurring mutants I172N, V281L and I236n/V237E/M239K exert a dominant negative effect on enzymatic activity when co-expressed with the wild-type protein. | 2003 Sep |
1 |
| 19 |
11250647 | Bioavailability of oral hydrocortisone in patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency. | 2001 Apr |
1 |
| 20 |
8989258 | Synergistic effect of partially inactivating mutations in steroid 21-hydroxylase deficiency. | 1997 Jan |
1 |
| 21 |
9187661 | A cluster of missense mutations at Arg356 of human steroid 21-hydroxylase may impair redox partner interaction. | 1997 Jun |
1 |
| 22 |
7479886 | Gene conversions and unequal crossovers between CYP21 (steroid 21-hydroxylase gene) and CYP21P involve different mechanisms. | 1995 Nov 7 |
2 |
| 23 |
1937474 | Substitution of Ile-172 to Asn in the steroid 21-hydroxylase B (P450c21B) gene in a Finnish patient with the simple virilizing form of congenital adrenal hyperplasia. | 1991 Oct |
1 |
| 24 |
1979956 | Defective, deleted or converted CYP21B gene and negative association with a rare restriction fragment length polymorphism allele of the factor B gene in congenital adrenal hyperplasia. | 1990 Dec |
1 |
| 25 |
2233746 | Expression of human 21-hydroxylase (P450c21) in bacterial and mammalian cells: a system to characterize normal and mutant enzymes. | 1990 Jun |
1 |
| 26 |
2249999 | Determination of functional effects of mutations in the steroid 21-hydroxylase gene (CYP21) using recombinant vaccinia virus. | 1990 Dec 5 |
1 |